References of "Detroz, Bernard"
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See detailIntraperitoneal hyperthermic chemotherapy (IPHC) for treatment of peritoneal carcinomatosis
Detroz, Bernard ULg; Marchettini, P.; Joris, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2001, January), 64(1), 80

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See detailStricturoplasty in Crohn disease: short and long term follow up
Laurent, Stanislas; Detry, Olivier ULg; Detroz, Bernard ULg et al

in Acta Gastro-Enterologica Belgica (2001, January), 64(1), 73

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See detail120 laparoscopic sigmoidectomies in diverticulitis: a 9 years experience
Detroz, Bernard ULg; Moscato; Detry, Olivier ULg et al

in Acta Gastro-Enterologica Belgica (2001, January), 64(1), 49

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See detailRadiofrequency ablation of liver tumors: short term evaluation
Detry, Olivier ULg; Detroz, Bernard ULg; Preud'Homme, Laurence ULg et al

in Acta Gastro-Enterologica Belgica (2001, January), 64(1), 11

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See detailRecommandations en matiere de traitement du cancer rectal
Gast, Pierrette ULg; Bours, Vincent ULg; Detroz, Bernard ULg et al

in Revue Médicale de Liège (2000), 55(5), 350-5

Curative resection of primary tumor and metastases is the only way to obtain a prolonged survival. Several additional treatments are under evaluation; some are already routinely proposed, in order to ... [more ▼]

Curative resection of primary tumor and metastases is the only way to obtain a prolonged survival. Several additional treatments are under evaluation; some are already routinely proposed, in order to reduce the tumor size and to allow surgery, to reduce the recurrence rate, and to give a better survival in case of unresectable metastases. Even in case of unresectable metastases, resection of the primary tumor should be envisaged, as quality of life with an evolving rectal tumor is very poor. [less ▲]

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See detailIntérêt de la tomographie a émission de positons dans l'évaluation des tumeurs digestives
Hustinx, Roland ULg; Paulus, Patrick; Daenen, Frédéric ULg et al

in Revue Médicale de Liège (1999), 54(12), 925-30

Imaging and endoscopic techniques have taken an increasing part in the management of gastroenterological disorders. Among these techniques, FDG-PET imaging has emerged as a powerful tool in the management ... [more ▼]

Imaging and endoscopic techniques have taken an increasing part in the management of gastroenterological disorders. Among these techniques, FDG-PET imaging has emerged as a powerful tool in the management of several cancer diseases, including tumors of the digestive tract. In particular, the role of PET for diagnosing and staging recurrent colorectal cancers, and for differentiating mass forming pancreatitis from carcinoma is now well established. In this review, we will briefly discuss the place of PET imaging in the work-up of the tumors of the digestive tract. [less ▲]

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See detailInteret clinique de la tomographie a emission de positons dans la detection et le bilan d'extension des recidives des cancers colorectaux
Hustinx, Roland ULg; Paulus, P.; Daenen, Frédéric ULg et al

in Gastroentérologie Clinique et Biologique (1999), 23(3), 323-9

BACKGROUND: Positron emission tomography (PET) has been shown useful for the staging of patients with various carcinomas. METHODS: We have applied this technique to 54 cases of colorectal carcinoma and ... [more ▼]

BACKGROUND: Positron emission tomography (PET) has been shown useful for the staging of patients with various carcinomas. METHODS: We have applied this technique to 54 cases of colorectal carcinoma and compared it to conventional imaging techniques. RESULTS: PET had moderately higher sensitivity and specificity than conventional techniques to detect individual lesion sites (75% vs 70.8% and 63% vs 21% respectively). It detected the same number of patients with recurrences (35/39) but overestimated disease less frequently (5 cases vs 12). PET favorably influenced therapeutic management in 17 patients, indicating different or additional surgery in 9 while avoiding surgery with curative intent or unnecessary surgery in 8. In 5 cases, erroneous information provided by PET could be corrected by conventional imaging techniques. CONCLUSION: We conclude that PET appears to provide complementary information useful for staging patients with colorectal carcinomas. It can significantly modify patients management. These data should be confirmed by a prospective study. [less ▲]

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See detailRepeated Cycles of Retrovirus-Mediated Hsvtk Gene Transfer Plus Ganciclovir Increase Survival of Rats with Peritoneal Carcinomatosis
Princen, Frédéric; Lechanteur, Chantal ULg; Lopez Y Cadenas, Miguel ULg et al

in Gene Therapy (1998), 5(8), 1054-60

Peritoneal carcinomatosis is a common clinical situation that requires novel therapeutic approaches. We investigated the efficiency of an HSVtk gene therapy for the treatment of peritoneal carcinomatosis ... [more ▼]

Peritoneal carcinomatosis is a common clinical situation that requires novel therapeutic approaches. We investigated the efficiency of an HSVtk gene therapy for the treatment of peritoneal carcinomatosis induced in syngeneic rats by DHD/K12 colon carcinoma cells. In this setting, the efficiency of two different retrovirus producing cell lines (GP+AmEnv12 and FLYA13) was compared. Rats treated with a single injection of retrovirus producing cells followed by a 5-day course of ganciclovir treatment showed an increased survival as compared with control animals. Animals treated with three injections of producing cells, each followed by a 4-5-day course of ganciclovir treatment, showed an increased survival as compared with control rats and with those treated with a single cycle of retrovirus producing cells plus ganciclovir. However, only a few animals remained tumor-free after day 180. There was no difference between the two producing cell lines in any of the experiments. RT-PCR demonstrated a faint expression of the tk transgene in the liver, spleen, epiploon, bowels and the lung of the animals injected with the HSVtk producing cells, reflecting most likely the transduction of only a limited number of cells. [less ▲]

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See detailHsv-1 Thymidine Kinase Gene Therapy for Peritoneal Carcinomatosis
Lechanteur, Chantal ULg; Princen, Frédéric; Lo Bue, S. et al

in Advances in Experimental Medicine and Biology (1998), 451

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See detailHsv-1 Thymidine Kinase Gene Therapy for Colorectal Adenocarcinoma-Derived Peritoneal Carcinomatosis
Lechanteur, Chantal ULg; Princen, Frédéric; Lo Bue, S. et al

in Gene Therapy (1997), 4(11), 1189-94

Peritoneal carcinomatosis is a common clinical situation which, in most cases, cannot be eradicated by surgery or chemotherapy. The feasibility of an HSV-TK-based suicide gene therapy for peritoneal ... [more ▼]

Peritoneal carcinomatosis is a common clinical situation which, in most cases, cannot be eradicated by surgery or chemotherapy. The feasibility of an HSV-TK-based suicide gene therapy for peritoneal carcinomatosis induced by DHD/K12 colon carcinoma cells was investigated. DHD/K12 cells stably expressing the tk gene were killed in vitro in the presence of low concentrations of ganciclovir, they exhibited a 'bystander effect' when mixed with TK-negative cells. BD-IX rats injected intraperitoneally, either directly or after surgical peritoneal irritations, with DHD/K12 cells developed peritoneal carcinomatosis within 2 weeks. Ganciclovir treatment of animals injected with DHD/K12-TK cells allowed a significant reduction of the tumor volume as well as a prolonged survival. Of these animals 35-40% showed a long-term disease-free survival after ganciclovir therapy. Residual or relapsing tumors could be explained by a low expression of the transgene as demonstrated by RT-PCR. [less ▲]

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See detailMisdiagnosed malignancy in transplanted organs
Detry, Olivier ULg; Detroz, Bernard ULg; D'Silva, Milbor et al

in Touraine, J. L.; Traeger, J.; Bétuel, H. (Eds.) et al Cancer in Transplantation: Prevention and Treatment (1996)

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See detailMisdiagnosed malignancy in transplanted organs
Detry, Olivier ULg; Detroz, Bernard ULg; D'Silva, Milbor et al

in Touraine, J. L.; Traeger, J.; Bétuel, H. (Eds.) et al Cancer in Transplantation: Prevention and Treatment (1996)

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See detailApproche thérapeutique du cancer épithélial de l'ovaire au CHU Sart Tilman : Conclusions de la réunion interdisciplinaire du 22 mars 1995
Jerusalem, Guy ULg; Detroz, Bernard ULg; Herman, Philippe ULg et al

in Revue Médicale de Liège (1995), 50

Notre but est de définir une approche multidisciplinaire permettant d'offrir les meilleures chances de guérison ou de survie prolongée aux patientes. Nous nous sommes basés sur notre expérience ... [more ▼]

Notre but est de définir une approche multidisciplinaire permettant d'offrir les meilleures chances de guérison ou de survie prolongée aux patientes. Nous nous sommes basés sur notre expérience personnelle et les données actuelles de la littérature, tout en intégrant les approches innovatrices (ex : chimiothérapie intrapéritonéale précoce). Pour certaines patientes, le pronostic reste trop sombre avec un traitement standard et il nous semble important de leur proposer un traitement potentiellement plus efficace. [less ▲]

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See detailTransplantations de tumeurs malignes insoupçonnées lors de greffes d'organes
Detry, Olivier ULg; Detroz, Bernard ULg; D'Silva, M. et al

in Revue Médicale de Liège (1994), 49(1), 23-31

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See detailThe treatment of amiodarone-induced hyperthyroidism. Is there a place for surgery?
Meurisse, Michel ULg; Detroz, Bernard ULg; Messens, D. et al

in Acta Chirurgica Belgica (1994), 94(1), 36-41

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced ... [more ▼]

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced thyrotoxicosis has also been described. Conventional treatments such as with antithyroid drugs (Thionamide) and corticosteroids are essentially ineffective or fail to stop the dramatic course of the thyroid crisis. This limited efficacy of medical therapy, particularly in patients with previously--neglected or unknown--thyroid disease, prompted us to intervene surgically. We report a series of six patients who underwent total or nearly total thyroidectomy as first line therapy for four of them. Surgery resulted in rapid resolution of thyrotoxicosis with an uneventful postoperative course. This approach has the advantage of immediate and safe efficacy, low risk of relapse and finally, appears to be the only antithyroid treatment that permits continued therapy with amiodarone. [less ▲]

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See detailMisdiagnosed Malignancy in Transplanted Organs
Detry, Olivier ULg; Detroz, Bernard ULg; D'Silva, M. et al

in Transplant International (1993), 6(1), 50-4

The case reports of three patients who received cancer-bearing organs at this institution are presented. A fourth recipient, who was to be transplanted with a cancerous kidney, was spared this disastrous ... [more ▼]

The case reports of three patients who received cancer-bearing organs at this institution are presented. A fourth recipient, who was to be transplanted with a cancerous kidney, was spared this disastrous complication. The relevant data regarding the donors is also alluded to, with special reference to the type and site of the primary malignancy. Following these case reports, the implications of these issues, their possible prevention, and further management are discussed. [less ▲]

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See detailCombined treatment of liver failure and hepatorenal syndrome with orthotopic liver transplantation
Detroz, Bernard ULg; Honore, Pierre ULg; Monami, B. et al

in Acta Gastro-Enterologica Belgica (1992), 55(4), 350-357

Hepatorenal syndrome (HRS) is a severe complication of liver failure with high mortality. The pathogenesis of this reversible functional renal failure is not yet clearly understood. Diagnosis is based ... [more ▼]

Hepatorenal syndrome (HRS) is a severe complication of liver failure with high mortality. The pathogenesis of this reversible functional renal failure is not yet clearly understood. Diagnosis is based upon the association of clinical and biological criteria. A patient was admitted to our institution for severe liver failure secondary to an exacerbation of cirrhosis, where he developed a fulminant hepatorenal syndrome. Both, the renal and hepatic failure were successfully treated by orthotopic liver transplantation. Special attention was paid to the immunosuppressive treatment with Cyclosporine whose use, we believe, should be delayed until function has partially recovered. [less ▲]

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See detail"Arterialization", "revascularization" , "rearterialization" - what's in a name?
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULg et al

in Transplant International (1992), (5), 121-122

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See detailRésection hépatique ex situ
Honoré, Pierre ULg; D'Silva, Milbhor; Meurisse, Michel ULg et al

in Médecine & Chirurgie Digestives (1992), 21

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See detailRésection hépatique ex situ
Honore, Pierre ULg; D'Silva, M.; Meurisse, Michel ULg et al

in Revue Médicale de Liège (1991), 46(11), 602-6

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