References of "Detilleux, Johann"
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See detailExercise and pharmacological stress echocardiography in healthy horses
Sandersen, Charlotte ULg; Detilleux, Johann ULg; Art, Tatiana ULg et al

in Equine Veterinary Journal. Supplement (2006), 37

REASONS FOR PERFORMING STUDY: Stress echocardiography could be a useful diagnostic test in horses suspected to suffer from exercise-induced myocardial dysfunction as a cause of exercise intolerance ... [more ▼]

REASONS FOR PERFORMING STUDY: Stress echocardiography could be a useful diagnostic test in horses suspected to suffer from exercise-induced myocardial dysfunction as a cause of exercise intolerance. OBJECTIVE: To evaluate the effect of treadmill exercise and pharmacological stress test on left ventricular echocardiographic parameters. METHODS: Echocardiography was performed in 2 groups of 5 healthy horses, either immediately after a near-maximal treadmill exercise (Group EXE) or during a pharmacological challenge (Group DOB) consisting of 35 microg/kg atropine, followed by incremental dobutamine infusion rates of 2-6 microg/kg bwt/min for 5 min duration each, which led to a cumulative dobutamine dose of 100 microg/kg. Left ventricular M-mode parameters were compared at rest and at heart rates of 80, 100, 110, 120 130, and 140 beats/min, within each group. RESULTS: In 2 horses of Group EXE, echocardiographic measurements were impossible at 140 and 130 beats/min, as their heart rates dropped too fast in the immediate post exercise period. In the remaining 3 horses image quality was not always satisfactory at heart rates of 130 and 140 beats/min. Systolic left ventricular parameters and fractional shortening measured at 130 and 140 beats/min were significantly different from values obtained at lower heart rates. Horses in Group DOB reached expected heart rates of 80 and 100 beats/min, after the administration of atropine and during a dobutamine infusion rate of 2 microg/kg bwt/min, respectively. Heart rates targets of 110, 120, 130, and 140 beats/min were reached at mean (+/- s.d.) dobutamine infusion rates of 2.8 +/- 0.4, 3.2 +/- 0.4, 4.0 +/- 0.7, 5 +/- 0.7 microg/kg bwt/min, respectively. Systolic left ventricular parameters and fractional shortening at heart rates of 110, 120, 130, and 140 beats/min, were significantly different from values obtained at lower heart rates. CONCLUSION: The pharmacological stress test induced changes in ventricular dimensions at heart rates of 80 to 140 beats/min. Using this test, high quality images can easily be obtained at heart rates of 140 beats/min. Conversely, in post exercise echocardiography, obtaining good quality images at heart rates of 130 and 140 beats/min is difficult, which limits use of the technique in routine clinical settings. POTENTIAL RELEVANCE: Further studies should demonstrate the potential of pharmacological stress test as a diagnostic tool in horses suffering from exercise-induced myocardial dysfunction. [less ▲]

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See detailCardiac pumping reserve measured in healthy horses using a dobutamine stress test
Sandersen, Charlotte ULg; Detilleux, Johann ULg; Art, Tatiana ULg et al

in Proceedings of the 45th Congress of the British Equine Veterinary Association (2006)

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See detailExercise and pharmacological echocardiography stress in healthy horses
Sandersen, Charlotte ULg; Detilleux, Johann ULg; Art, Tatiana ULg et al

in Proceedings of the 7th ICEEP (Equine veterinary supplement 206, 36:159-162) (2006)

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See detailExamination of non-genetics factors affecting the growth performance of Djallonke sheep at the Okpara breeding farm in Soudanian zone of Benin
Gbangboche, A. B.; Senou, N.; Farnir, Frédéric ULg et al

in Tropical Animal Health and Production (2006), 38(1), 55-64

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See detailNon-genetic factors affecting the reproduction performance, lamb growth and productivity indices of Djallonke sheep
Gbangboche, A. B.; Adamou-Ndiaye, M.; Youssao, A. K. I. et al

in Small Ruminant Research (2006), 64((1-2)), 133-142

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See detailEvaluation of respiratory function by barometric whole-body plethysmography in healthy dogs
Talavera, J.; Kirschvink, N.; Schuller, S. et al

in Veterinary Journal (2006), 172(1), 67-77

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate ... [more ▼]

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate airway responsiveness using BWBP in healthy dogs. BWBP measurements were obtained from six healthy beagle dogs using different protocols: (1) during three consecutive periods (3.5 min each) in two morning and two evening sessions; (2) before and after administration of two protocols of sedation; (3) before and after nebulisation of saline and increasing concentrations of carbachol and histamine both in conscious dogs and in dogs under both protocols of sedation. Enhanced pause (PENH) was used as index of bronchoconstriction. Basal BWBP measurements were also obtained in 22 healthy dogs of different breeds, age and weight. No significant influence of either time spent in the chamber or daytime was found for most respiratory variables but a significant dog effect was detected for most variables. A significant body weight effect was found on tidal volume and peak flow values (P < 0.05). Response to carbachol was not reproducible and always associated with side effects. Nebulisation of histamine induced a significant increase in respiratory rate, peak expiratory flow, peak expiratory flow/peak inspiratory flow ratio and PENH (P < 0.05). The response was reproduced in each dog at different concentrations of histamine. Sedation with acepromazine + buprenorphine had little influence on basal measurements and did not change the results of histamine challenge. It was concluded that BWBP is a safe, non invasive and reliable technique of investigation of lung function in dogs which provides new opportunities to characterise respiratory status, to evaluate airway hyperresponsiveness and to assess therapeutic interventions. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

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See detailProlactine triggers a pro-inflamatory response in bovine mammary epithelial cells
Boutet, Philippe ULg; Sulon, Joseph; Detilleux, Johann ULg et al

in Proceedings: 24th World Buiatrics Congress (2006)

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See detailEffect of atropine-dobutamine stress test on left ventricular echocardio graphic parameters in untrained warmblood horses
Sandersen, Charlotte ULg; Detilleux, Johann ULg; De Moffarts, Brieux et al

in Journal of Veterinary Internal Medicine (2006)

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See detailStatistical relations between obesity in dogs and associated diseases
Swiontek, V.; Detilleux, Johann ULg; Herry, J. et al

in Congress Proceedings 10th Congress of the ESVCN (2006)

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See detailMathematical model of the acute inflammatory response to Escherichia coli in intramammary challenge
Detilleux, Johann ULg; Vangroenweghe, F.; Burvenich, C.

in Journal of Dairy Science (2006), 89(9), 3455-3465

We constructed a mathematical model of the early response to Escherichia coli infection of the mammary gland and explored the roles and interactions between inflammatory cells and bacteria. The model ... [more ▼]

We constructed a mathematical model of the early response to Escherichia coli infection of the mammary gland and explored the roles and interactions between inflammatory cells and bacteria. The model incorporates 3 equations that describe the interactions among bacteria, milk somatic cells, and blood leukocyte densities. These 3 equations were fitted to cell densities observed during acute inflammatory responses in unvaccinated and vaccinated heifers inoculated with 10(4) or 10(6) cfu of E. coli. The rates computed for the cellular transit from the storage sites to the blood and from the blood to the milk were lower in cows receiving 10(4) cfu but increased at approximately 6 x 10(-6) and 30 x 10(-6) microL/cfu per h in nonvaccinated or vaccinated cows inoculated with 10(6) cfu, respectively. The cellular rates of bacterial killing were highest in unvaccinated cows ( approximately 400 x 10(-6) microL/cell per h) when compared with vaccinated cows (200 to 300 x 10(-6) microL/cell per h). A critical density of milk somatic cells at which bacteria density is constant was computed from the model at 2 x 10(6) cells/mL, and a one-way sensitivity analysis revealed that the changes in milk cellular densities were mostly sensitive to variations in the rate of bacterial killing and in the rate of production of inflammatory cells. [less ▲]

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See detailLaryngeal paralysis-polyneuropathy complex in young related Pyrenean Mountain dogs.
Gabriel, Alexandra; Poncelet, Luc; Van Ham, Luc et al

in Journal of Small Animal Practice (2006), 47(3)

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See detailIs There a Difference Between Energy Balance of Cats Hospitalised for Surgical or for Medical Reasons?
Lhoest, Estelle; Claeys, Stéphanie ULg; Gabriel, Alexendra et al

in Journal of Veterinary Internal Medicine (2005, November), 19(6), 939

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See detailEpidémiologie de l’obésité canine en Belgique et en France
Lhoest, Estelle; Detilleux, Johann ULg; Vandenheede, Marc ULg et al

in Le Nouveau praticien vétérinaire (2005)

Etude épidémiologique de l'obésité canine auprès de 517 propriétaires de chiens de race prédisposée à l'obésité. Les facteurs favorisant l'obésité sont répertoriés et quantifiés

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See detailAnalysis of Canine and Feline uroliths in the Benelux. A retrospective study : 1994-2004
De Lovinfosse, Tanguy; Detilleux, Johann ULg; Picavet, Philippe et al

Poster (2005, April)

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See detailPrognostic value of clinical signs and blood parameters in equids suffering from hepatic diseases
Amory, Hélène ULg; Perron, M. F.; Sandersen, Charlotte ULg et al

in Journal of Equine Veterinary Science (2005), 25(1), 18-25

The purpose of this retrospective study was to further identify in the equine species the clinical signs and blood parameters that could be useful to identify a hepatic disease and act as predictors of ... [more ▼]

The purpose of this retrospective study was to further identify in the equine species the clinical signs and blood parameters that could be useful to identify a hepatic disease and act as predictors of the outcome in animals suffering from an acute hepatic insufficiency. The study included 31 equids that were hospitalized at the University of Liege and that suffered from a hepatic (group 1, 17 cases of hepatitis; group 2, 11 cases of hyperlipemia) or post-hepatic (group 3, 3 cases of cholelithiasis) disease. Frequency of the clinical signs and values of selected blood parameters on admission were compared statistically between surviving and non-surviving animals. The most frequently presented clinical signs were depression, decreased appetite or anorexia, fever, tachycardia, polypnea, icterus, and congested mucous membranes. Frequency of the clinical signs and blood parameter values were not statistically different in surviving and non-surviving animals, with the exception of gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP), which were significantly higher in animals with fatal outcome, with a cutoff value of 224 and 820 IU/L, respectively. [less ▲]

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See detailGenetic management of infectious diseases: An heterogeneous epidemio-genetic model illustrated with S. aureus mastitis
Detilleux, Johann ULg

in Genetics, Selection, Evolution (2005), 37(4), 437-453

Given that individuals are genetically heterogeneous in their degree of resistance to infection, a model is proposed to formulate appropriate choices that will limit the spread of an infectious disease ... [more ▼]

Given that individuals are genetically heterogeneous in their degree of resistance to infection, a model is proposed to formulate appropriate choices that will limit the spread of an infectious disease. The model is illustrated with data on S. aureus mastitis and is based on parameters characterizing the spread of the disease (contact rate, probability of infection after contact, and rate of recovery after infection), the demography (replacement and culling rates) and the genetic composition (degree of relationship and heritability of the disease trait) of the animal population. To decrease infection pressure, it is possible to apply non-genetic procedures that increase the culling (e.g., culling of chronically infected cows) and recovery (e.g., antibiotic therapy) rates of infected cows. But the contribution of the paper is to show that genetic management of infectious disease is also theoretically possible as a control measure complementary to non-genetic actions. Indeed, the probability for an uninfected individual to become infected after contact with an infected one is partially related to their degree of kinship: the more closely they are related, the more likely they are to share identical genes like those associated to the non-resistance to infection. Different prospective genetic management procedures are proposed to decrease the contact rate between infected and uninfected relatives and keep the number of secondary cases generated by one infected animal below 1. [less ▲]

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See detailA comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds
Boutet, Philippe; Detilleux, Johann ULg; Motkin, Michel ULg et al

in Annales de Médecine Vétérinaire (2005), 149(3), 173-182

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease ... [more ▼]

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease affecting dairy cows. The fluctuating increase in somatic cell count (SCC) that occurs causes major economic losses in dairy industry. This comparative study between conventional and organic dairy herds was conducted in the aim to better characterize which consequences might have different management practices on SCC but also on the frequency of pathogens isolated and their antimicrobial susceptibility. Four conventional and four organic herds, with bulk milk SCC >300x103cells/ml were selected, in which respectively 47 and 44 cows were investigated. Each quarter was sampled 3 times at 15 days interval for SCC, microbiological analysis and antimicrobial susceptibility. In both herd categories, major pathogens isolated were by order of importance Streptococcus uberis, Staphylococcus aureus and Streptococcus dysgalactiae with a great impact on SCC. Coagulase negative staphylococci were the most frequent minor germs and had a moderated but real impact on SCC. In certified organic dairy farms, the three most frequently isolated major pathogens were significantly more susceptible to antimicrobials in vitro. This study suggests that the limited use of antibiotics in organic dairy herds could explain, at least in part, the lower resistance obtained from analysed isolates. [less ▲]

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See detailReference values for left ventricular echocardiographic parameters during atropine/dobutamine stress testing
Sandersen, Charlotte ULg; Detilleux, Johann ULg; De Moffarts, Brieuc et al

in Proceedings of the 44th Annual Congress of the British Equine Veterinary Association (BEVA) (2005)

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