References of "Detilleux, Johann"
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See detailIs There a Difference Between Energy Balance of Cats Hospitalised for Surgical or for Medical Reasons?
Lhoest, Estelle; Claeys, Stéphanie ULg; Gabriel, Alexendra et al

in Journal of Veterinary Internal Medicine (2005, November), 19(6), 939

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See detailEpidémiologie de l’obésité canine en Belgique et en France
Lhoest, Estelle; Detilleux, Johann ULg; Vandenheede, Marc ULg et al

in Le Nouveau praticien vétérinaire (2005)

Etude épidémiologique de l'obésité canine auprès de 517 propriétaires de chiens de race prédisposée à l'obésité. Les facteurs favorisant l'obésité sont répertoriés et quantifiés

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See detailGenetic management of infectious diseases: An heterogeneous epidemio-genetic model illustrated with S. aureus mastitis
Detilleux, Johann ULg

in Genetics, Selection, Evolution (2005), 37(4), 437-453

Given that individuals are genetically heterogeneous in their degree of resistance to infection, a model is proposed to formulate appropriate choices that will limit the spread of an infectious disease ... [more ▼]

Given that individuals are genetically heterogeneous in their degree of resistance to infection, a model is proposed to formulate appropriate choices that will limit the spread of an infectious disease. The model is illustrated with data on S. aureus mastitis and is based on parameters characterizing the spread of the disease (contact rate, probability of infection after contact, and rate of recovery after infection), the demography (replacement and culling rates) and the genetic composition (degree of relationship and heritability of the disease trait) of the animal population. To decrease infection pressure, it is possible to apply non-genetic procedures that increase the culling (e.g., culling of chronically infected cows) and recovery (e.g., antibiotic therapy) rates of infected cows. But the contribution of the paper is to show that genetic management of infectious disease is also theoretically possible as a control measure complementary to non-genetic actions. Indeed, the probability for an uninfected individual to become infected after contact with an infected one is partially related to their degree of kinship: the more closely they are related, the more likely they are to share identical genes like those associated to the non-resistance to infection. Different prospective genetic management procedures are proposed to decrease the contact rate between infected and uninfected relatives and keep the number of secondary cases generated by one infected animal below 1. [less ▲]

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See detailA comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds
Boutet, Philippe; Detilleux, Johann ULg; Motkin, Michel ULg et al

in Annales de Médecine Vétérinaire (2005), 149(3), 173-182

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease ... [more ▼]

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease affecting dairy cows. The fluctuating increase in somatic cell count (SCC) that occurs causes major economic losses in dairy industry. This comparative study between conventional and organic dairy herds was conducted in the aim to better characterize which consequences might have different management practices on SCC but also on the frequency of pathogens isolated and their antimicrobial susceptibility. Four conventional and four organic herds, with bulk milk SCC >300x103cells/ml were selected, in which respectively 47 and 44 cows were investigated. Each quarter was sampled 3 times at 15 days interval for SCC, microbiological analysis and antimicrobial susceptibility. In both herd categories, major pathogens isolated were by order of importance Streptococcus uberis, Staphylococcus aureus and Streptococcus dysgalactiae with a great impact on SCC. Coagulase negative staphylococci were the most frequent minor germs and had a moderated but real impact on SCC. In certified organic dairy farms, the three most frequently isolated major pathogens were significantly more susceptible to antimicrobials in vitro. This study suggests that the limited use of antibiotics in organic dairy herds could explain, at least in part, the lower resistance obtained from analysed isolates. [less ▲]

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See detailReference values for left ventricular echocardiographic parameters during atropine/dobutamine stress testing
Sandersen, Charlotte ULg; Detilleux, Johann ULg; De Moffarts, Brieuc et al

in Proceedings of the 44th Annual Congress of the British Equine Veterinary Association (BEVA) (2005)

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See detailCost-effectiveness analysis applied to the veterinary medicine: The economic value of packed cell value in the prognosis of horse surgical colic
Detilleux, Johann ULg; Serteyn, Didier ULg

in International Journal of Applied Research in Veterinary Medicine (2005), 3(4), 309-318

Techniques of cost-effectiveness analyses were applied to determine whether or not it is economically efficient to measure the packed cell volume (PCV) on a colic horse before deciding on abdominal ... [more ▼]

Techniques of cost-effectiveness analyses were applied to determine whether or not it is economically efficient to measure the packed cell volume (PCV) on a colic horse before deciding on abdominal surgery. The effects of this decision of uncertainty on the estimated values of the parameters (probability of survival after surgery, surgery costs, PCV positive predictive value, and length of survival after surgery) were considered along with the monetary values of collecting additional information on those parameters. The effects of uncertainty on the incremental net benefits of each alternative were depicted by tornado diagrams, cost-effectiveness acceptability curves, and posterior probability distributions. The worth of additional information was computed as the expected values of perfect and sampling information. Given previously published results, the best PCV cut-off point to distinguish between survivors and nonsurvivors was at 44%. At this threshold, the most economically effective alternative is to measure PCV before surgery providing the owner is willing to pay less than €672 for each year the horse survives. Uncertainty on probability of survival after surgery largely influenced the decision whether or not to measure the PCV, but one should spend at most €381 in research to reduce this uncertainty. A study of postoperative survival of 500 colic horses would ensure an expected gain of €370 associated with a reduction in uncertainty. [less ▲]

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See detailEffects of chronic obesity and weight loss on plasma ghrelin and leptin concentrations in dogs.
Jeusette, Isabelle C; Detilleux, Johann ULg; Shibata, Haruki et al

in Research in Veterinary Science (2005), 79(2), 169-75

The objective of this study was to evaluate, in dogs, the effects of obesity and weight loss on plasma total ghrelin and leptin concentrations. Twenty-four Beagle dogs, 12 control lean and 12 obese dogs ... [more ▼]

The objective of this study was to evaluate, in dogs, the effects of obesity and weight loss on plasma total ghrelin and leptin concentrations. Twenty-four Beagle dogs, 12 control lean and 12 obese dogs of both genders and aged between 1 and 9 years, were used for the experiments. Mean body weight was 12.7+/-0.7 kg for the lean group and 21.9+/-0.8 kg for the obese group. The trial was divided into three phases. During phase 1, all 24 Beagle dogs were fed a maintenance diet. During phase 2, the obese dogs were submitted to a weight loss protocol with a high protein-low energy diet. The weight loss protocol ended once dogs reached optimal body weight. During phase 3, the dogs that were submitted to the weight loss protocol were maintained at their optimal body weight for 6 months. Plasma total ghrelin, leptin, insulin and glucose concentrations were measured to evaluate the effects of obesity and weight loss on these parameters in dogs. Body weight, body condition score, thoracic and pelvic perimeters, and ingested food amounts were also recorded during the study. Obese dogs demonstrated a significant decrease in plasma ghrelin and a significant increase in plasma leptin and insulin concentrations when compared with control dogs. During weight loss, significant increases in plasma total ghrelin and glucose and significant decreases in plasma leptin and insulin were observed. The increase in plasma ghrelin concentrations seemed to be transient. Body weight and the morphometric parameters correlated positively with leptin concentrations and negatively with total ghrelin concentrations. These results suggest that ghrelin and leptin could play a role in dogs in the adaptation to a positive or negative energy balance, as observed in humans. [less ▲]

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See detailAn epidemiological study of canine obesity
Lhoest, E.; Detilleux, Johann ULg; Vandenheede, Marc ULg et al

Conference (2005)

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See detailHow vets and veterinary students feed their own dogs
Lhoest, E.; Detilleux, Johann ULg; Vandenheede, M. et al

in Proceedings of the 9th Congress ESVCN (2005)

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See detailAnalysis of canine and feline uroliths in the Benelux. A retrospective study 1994-2005
de Lovinfosse, T.; Detilleux, Johann ULg; Picavet, P. et al

in Proceedings of the 9th Congress ESVCN (2005)

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See detailThyroid hormones in obese dogs submitted to a weight loss protocol
Jeusette, Isabelle; Daminet, Sylvie; Detilleux, Johann ULg et al

in Obesity Reviews : An Official Journal of the International Association for the Study of Obesity (2005), 6

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See detailMixture model for inferring susceptibility to mastitis in dairy cattle: a procedure for likelihood-based inference
Gianola, D.; Odegard, J.; Heringstad, B. et al

in Genetics, Selection, Evolution (2004), 36(1, JAN-FEB), 3-27

A Gaussian mixture model with a finite number of components and correlated random effects is described. The ultimate objective is to model somatic cell count information in dairy cattle and to develop ... [more ▼]

A Gaussian mixture model with a finite number of components and correlated random effects is described. The ultimate objective is to model somatic cell count information in dairy cattle and to develop criteria for genetic selection against mastitis, an important udder disease. Parameter estimation is by maximum likelihood or by an extension of restricted maximum likelihood. A Monte Carlo expectation- maximization algorithm is used for this purpose. The expectation step is carried out using Gibbs sampling, whereas the maximization step is deterministic. Ranking rules based on the conditional probability of membership in a putative group of uninfected animals, given the somatic cell information, are discussed. Several extensions of the model are suggested. [less ▲]

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See detailProduction des ovins Djallonké en station dans la zone guinéenne au Bénin : 1. Performances de reproduction et influence des facteurs non génétiques
Gbangboche, A. B.; Hounzangbe-Adote, S. M.; Doko, S. Y. et al

in Revue Africaine de Santé et de Productions Animales [=RASPA] (2004), 2

Production of Djallonke sheep at an experimental station in the guinean zone of Benin. Reproduction performance and influence of non-genetic factors From 1994 to 2002, data from Djallonke sheep were ... [more ▼]

Production of Djallonke sheep at an experimental station in the guinean zone of Benin. Reproduction performance and influence of non-genetic factors From 1994 to 2002, data from Djallonke sheep were collected for reproduction performance. The data were obtained from the farm of the Faculty of Agronomic Sciences (University of Abomey Calavi). Data analysed by GLM procedure and Student’s t-test, were used to identify and quantify non-genetics factors affecting the age at first lambing, intervals between lambing and prolificacy. Results indicated: age at first lambing, 609.64days±110.26 days; intervals between lambing, 243.01days±68.19days; prolificity, 1.28±0.45; annual reproduction rate, 1.92%; temporary sterility rate, 5.79%. Lambing season, lambing year and the year*season interaction affected significantly (p<0.01) the age at first lambing and the interval between lambing. The same factors were not significant (p>0.05) for prolificacy. [less ▲]

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See detailExtensive mast cell degranulation in bovine respiratory syncytial virus-associated paroxystic respiratory distress syndrome
Jolly, Sandra ULg; Detilleux, Johann ULg; Desmecht, Daniel ULg

in Veterinary Immunology and Immunopathology (2004), 97(3-4), 125-136

Bovine respiratory syncytial virus (BRSV) infection is an important cause of outbreaks of respiratory disease among calves. This virus commonly induces mild to severe respiratory signs but, in a ... [more ▼]

Bovine respiratory syncytial virus (BRSV) infection is an important cause of outbreaks of respiratory disease among calves. This virus commonly induces mild to severe respiratory signs but, in a substantial proportion of cases, is also reported to be associated with paroxystic respiratory distress syndrome (PRDS). The pathogenesis of this 'malignant' clinical form has not been fully elucidated. The present study aimed at determining whether mast cell (MC) degranulation plays a role in the physiopathologic cascade leading to the PRDS. Paired serum samples were taken in herds during outbreaks of severe respiratory diseases (acute sera) and 3 weeks after (convalescent sera). Based on seroconversion to BRSV and clinical picture, 67 pairs of sera were selected from calves with a BRSV-associated PRDS for circulating MC tryptase determination. A MC metachromatic score was measured in post-mortem lungs from animals died from a BRSV-associated PRDS (principals) and compared with reference scores obtained from healthy lungs (controls). Levels of tryptase were significantly higher in acute sera (26.6+/-12.4 mug/l) compared to convalescent sera (8.4+/-7.8 mug/l; P < 0.001). Metachromatic scores yielded significantly different results between controls and principals (P < 0.01), demonstrating a significant disappearance of metachromatic granules from lung MCs in principals. Taken together, these data demonstrate the presence of an extensive MC degranulation in BRSV-associated PRDS. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailSomatic Cell (Neutrophil) Counts in the War Against Staphylococcus aureus: Predator-Prey Models at the Rescue
Detilleux, Johann ULg

in Journal of Dairy Science (2004), 87(11), 3716-3724

To address the question of whether a minimum concentration of blood neutrophils is necessary to decrease Staphylococcus aureus concentration in mastitic milk, literature was searched for studies in which ... [more ▼]

To address the question of whether a minimum concentration of blood neutrophils is necessary to decrease Staphylococcus aureus concentration in mastitic milk, literature was searched for studies in which neutrophils were incubated with Staph. aureus. Different mathematical models that describe the changes in Staph. aureus population as a function of neutrophilic concentrations were applied to the collected data. The best fitted model established (1) that the rate of bacterial killing depended on the ratio of neutrophils to bacteria with neutrophilic attack rate accelerating at first before decelerating as the ratio increases, and (2) that neutro-phil concentration should be within a limited range to trigger a decline in the bacterial population. Outcomes of this model are supported by what is known about neutrophilic functions and laboratory findings in bovine and human neutrophils. These results may be of assistance in setting selection goals for a better resilience to Staph. aureus mastitis in dairy cattle. Indeed, an optimal neutrophilic concentration appears to exist for successful clearance of Staph. aureus infection, which is neither the lowest nor the highest one. [less ▲]

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See detailAd libitum feeding following ovariectomy in female Beagle dogs: effect on maintenance energy requirement and on blood metabolites.
Jeusette, Isabelle; Detilleux, Johann ULg; Cuvelier, Christine ULg et al

in Journal of Animal Physiology & Animal Nutrition (2004), 88(3-4), 117-21

The aim of this study was (i) to evaluate the effect of ovariectomy on daily energy requirement in Beagle dogs, and (ii) to evaluate the effects of ad libitum feeding with a high energy diet on energy ... [more ▼]

The aim of this study was (i) to evaluate the effect of ovariectomy on daily energy requirement in Beagle dogs, and (ii) to evaluate the effects of ad libitum feeding with a high energy diet on energy consumption, body weight gain and blood metabolites in these spayed dogs. Four young adult female Beagle dogs were used. Ovariectomy induced a significant decrease of daily energy requirement in dogs. Ad libitum feeding, initiated 6 months after spaying, induced a significant increase in consumption in spayed dogs. This overconsumption was greatest during the first month of ad libitum feeding but continued for the entire 4 months of this period. When fed ad libitum, dogs gained excess body weight without significant effect on plasma cholesterol, triglycerides, glucose and insulin, at short term. These data suggest that energy intake should be strictly controlled to avoid excess weight gain in spayed dogs. [less ▲]

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See detailStress echocardiography in horses: comparison of cardiac output during incremental dobutamine infusion in atropinised and non-atropinised ponies
Sandersen, Charlotte ULg; Detilleux, Johann ULg; Delguste, Catherine ULg et al

in Proceedings of the 42d Annual Congress of the British Equine Veterinairy Association (2003, September)

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