References of "Deneufbourg, Jean-Marie"
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See detailEvaluation des troubles salivaires et gustatifs après radiothérapie de cancers de la tête et du cou
Deneufbourg, Jean-Marie ULg; Lupo, Aurelia

in Revue Médicale de Liège (1986), XLI(17), 649-653

Salivary and taste impairments are the most frequent side-effects of radiotherapy among head and neck cancer patients.They were evaluated by interview, clinical examination, biological dosages and taste ... [more ▼]

Salivary and taste impairments are the most frequent side-effects of radiotherapy among head and neck cancer patients.They were evaluated by interview, clinical examination, biological dosages and taste assessment for sugar, salt, bitter and acid. Results confirm marked differences by comparison to a reference population with significant alterations from the point of view of quality of life. [less ▲]

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See detailSplit-Course Irradiation in the Treatment of Larynx Carcinoma
Deneufbourg, Jean-Marie ULg

in Chretien, Paul B. (Ed.) Program of Continuing Education University of Maryland School of Medicine : International Conference on Head and Neck Cancer, Baltimore July 22-27 1984 (1984, July 26)

A hypofractionated split course radiotherapy has been routinely used to treat 201 larynx cancer patients. Two irradiation periods of 6x4 Gy over 2 weeks are separated by a 15 days rest interval. The dose ... [more ▼]

A hypofractionated split course radiotherapy has been routinely used to treat 201 larynx cancer patients. Two irradiation periods of 6x4 Gy over 2 weeks are separated by a 15 days rest interval. The dose equivalent of 12 fractions of 4 Gy over 6 weeks is estimated to 63 Gy/30 fractions/6 weeks.By comparison with our historical controls, cure rates at 5 years proved effective (e.g. 87% for T1 glottic; 43% for T3+T4 supraglottic). The acute and delayed radiation side-effects have been less important with better functional results. [less ▲]

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See detailRadiocurability of a transplantable murine sarcoma as influenced by immune competence of the host and adjuvant active specific immunotherapy
Deneufbourg, Jean-Marie ULg

in Strahlentherapie (1975), 149(4), 457-462

The immunization induced in CBA mice by allogenic transplantation of sarcoma J was evaluated through the rejection rate of a subsequent isologous tumour graft. Female animals appear to be significantly ... [more ▼]

The immunization induced in CBA mice by allogenic transplantation of sarcoma J was evaluated through the rejection rate of a subsequent isologous tumour graft. Female animals appear to be significantly much more competent at various stages of sarcoma growth as after their definite cure by radiation or surgery. A difference of response according to the sex is also present with regard to the auto-immune reaction evoked by tumour irradiation. A marked discrepancy in radiotherapy efficiency is linked to the disparity of immune behaviour, emphasizing the fact that an immunological competent host constitutes an important factor of tumour radiocurability. In male recipients, an adjuvant active specific immunotherapy potentiates tumour response to a single dose of radiations. On the contrary, the adjunct treatment may display a detrimental effect in animals which already possess a high degree of anti-tumour immunization. [less ▲]

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