Du simple audit à l’amélioration continue de la qualité des pratiques dans le domaine de l’antibiothérapie
VERCHEVAL, Christelle ; DAMAS, Pierre ; Van Hees, Thierry
Poster (2013, March 02)Detailed reference viewed: 62 (16 ULg)
Do Maastricht category III donation after cardiovascular death (DCD) donors experience end-of-life shortening?
LEDOUX, Didier ; DELBOUILLE, Marie-Hélène ; DE ROOVER, Arnaud et al
Poster (2013, February 08)Detailed reference viewed: 29 (6 ULg)
Is extended or continuous infusion of Carbapenems the obvious solution to improve clinical outcomes and reduce mortality?
FRIPPIAT, Frédéric ; VERCHEVAL, Christelle ; LAMBERMONT, Bernard et al
in Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America (2013), 57(2), 324-325Detailed reference viewed: 20 (8 ULg)
Reduction in VAP incidence by subglottic secretion drainage and antibiotic consumption in ICU patients
VAN CAUWENBERGE, Isabelle ; ANCION, Arnaud ; LAMBERMONT, Bernard et al
in Intensive Care Medicine (2013), 39(Suppl 2), 465-4660898Detailed reference viewed: 24 (7 ULg)
La prise en charge précoce du patient brûlé en kinésithérapie.
REMY, Christophe ; JACQUEMIN, Denise ; MASSAGE, Patrick et al
in Réanimation (2013), 22(5), 543-551
Profonde ou atteignant une large surface cutanée, la brûlure engendre souvent des séquelles fonctionnelles impor- tantes. Ces séquelles se constituent précocement et ont des répercussions non négligeables ... [more ▼]
Profonde ou atteignant une large surface cutanée, la brûlure engendre souvent des séquelles fonctionnelles impor- tantes. Ces séquelles se constituent précocement et ont des répercussions non négligeables sur la qualité de vie des patients. Pour les prévenir et les traiter, le kinésithérapeute est un acteur important dans leur prise en charge précoce. Il devra évaluer les fonctions respiratoires, musculaires, orthopédiques mais également cutanées. L’objectif est de définir des stratégies de traitement faisant appel à des techniques de kinésithérapie classiques adaptées à cette pathologie spécifique. [less ▲]Detailed reference viewed: 90 (34 ULg)
From point prevalence surveys to continuous quality improvement in a teaching hospital in Belgium
VERCHEVAL, Christelle ; Van Hees, Thierry ; DAMAS, Pierre
Poster (2013)Detailed reference viewed: 10 (1 ULg)
Hypovitaminosis D and osteoporosis in burn patients: are the current practices enough ?
ROUSSEAU, Anne-Françoise ; LEDOUX, Didier ; DAMAS, Pierre et al
in Osteoporosis International (2013), 24(Suppl 1), 377Detailed reference viewed: 47 (17 ULg)
Evaluation d'un protocole de prise en charge nutritionnelle interdisciplinaire chez des patients brulés
MALHERBE, Christian ; VERBRUGGE, Anne-Marie ; MAGNETTE, André et al
in Nutrition Clinique et Metabolisme (2012, December), 26-Supp1Detailed reference viewed: 39 (10 ULg)
Clinical sedation and bispectral index in burn children receiving gamma-hydroxybutyrate.
ROUSSEAU, Anne-Françoise ; LEDOUX, Didier ; et al
in Paediatric Anaesthesia (2012), 22(8), 799-804
Background: Gamma-hydroxybutyrate (GHB) may be an interesting hypnotic agent in burn patients because of its good respiratory or hemodynamic tolerance. However, its clinical and electroencephalographic ... [more ▼]
Background: Gamma-hydroxybutyrate (GHB) may be an interesting hypnotic agent in burn patients because of its good respiratory or hemodynamic tolerance. However, its clinical and electroencephalographic (EEG) sedative effects are not yet described in children. The aim of this prospective and randomized study was to assess clinical and EEG effects of increasing intravenous (IV) doses of GHB in burn children requiring sedation for burn wound cares. Methods: Thirty six children hospitalized in a burn care unit were included and randomly assigned into three groups (G) according to the single IV dose of GHB they received before burn wound care: 10 mg·kg(-1) in G10, 25 mg·kg(-1) in G25, or 50 mg·kg(-1) in G50. All patients received oral premedication (morphine and hydroxyzine) 30 min before GHB injection. Respiratory rate, heart rate, pulse oximetry, and bispectral index (BIS) were continuously monitored. Depth of sedation was clinically assessed using Observer's Assessment of Alertness and Sedation (OAAS) Score, every 2 min until recovery (i.e., OAAS = 4). Results: Median age was 17.5 [12-34] months. Whatever the dose, BIS decreased after IV GHB. Nadir value of BIS was significantly lower in G25 and G50 than in G10, as was for OAAS score. Nadir values were reached after same delays in G25 and G50. Duration of sedation was dose-dependant. Conclusion: Bispectral index decreased after GHB injection and was correlated with OAAS score. Deep sedation can be safely achieved with IV doses of 25 or 50 mg·kg(-1) , but the last dose was associated with prolonged duration of clinical sedation. [less ▲]Detailed reference viewed: 52 (19 ULg)
Prise en charge des brûlés en phase aigue : enquête européenne.
ROUSSEAU, Anne-Françoise ; LEDOUX, Didier ; MASSION, Paul et al
in Brûlures. Revue Française de Brûlologie (2012, June), XIII(2), 60Detailed reference viewed: 46 (15 ULg)
Adaptation des traitements antibiotiques après 72 heures lors d'infection acquise en USI
; VERCHEVAL, Christelle ; NYS, Monique et al
in Réanimation (2012), 22(Suppl 2), 250033Detailed reference viewed: 16 (8 ULg)
Measuring end expiratory lung volume after cardiac surgery
MICHIELS, Grégoire ; ; LEDOUX, Didier et al
in Acta Anaesthesiologica Belgica (2012), 63(3), 115-120Detailed reference viewed: 15 (3 ULg)
Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients.
LAYIOS, Nathalie ; LAMBERMONT, Bernard ; CANIVET, Jean-Luc et al
in Critical Care Medicine (2012), 40(8), 2304-9
OBJECTIVES: : To test the usefulness of procalcitonin serum level for the reduction of antibiotic consumption in intensive care unit patients. DESIGN: : Single-center, prospective, randomized controlled ... [more ▼]
OBJECTIVES: : To test the usefulness of procalcitonin serum level for the reduction of antibiotic consumption in intensive care unit patients. DESIGN: : Single-center, prospective, randomized controlled study. SETTING: : Five intensive care units from a tertiary teaching hospital. PATIENTS: : All consecutive adult patients hospitalized for > 48 hrs in the intensive care unit during a 9-month period. INTERVENTIONS: : Procalcitonin serum level was obtained for all consecutive patients suspected of developing infection either on admission or during intensive care unit stay. The use of antibiotics was more or less strongly discouraged or recommended according to the Muller classification. Patients were randomized into two groups: one using the procalcitonin results (procalcitonin group) and one being blinded to the procalcitonin results (control group). The primary end point was the reduction of antibiotic use expressed as a proportion of treatment days and of daily defined dose per 100 intensive care unit days using a procalcitonin-guided approach. Secondary end points included: a posteriori assessment of the accuracy of the infectious diagnosis when using procalcitonin in the intensive care unit and of the diagnostic concordance between the intensive care unit physician and the infectious-disease specialist. MEASUREMENTS AND MAIN RESULTS: : There were 258 patients in the procalcitonin group and 251 patients in the control group. A significantly higher amount of withheld treatment was observed in the procalcitonin group of patients classified by the intensive care unit clinicians as having possible infection. This, however, did not result in a reduction of antibiotic consumption. The treatment days represented 62.6 +/- 34.4% and 57.7 +/- 34.4% of the intensive care unit stays in the procalcitonin and control groups, respectively (p = .11). According to the infectious-disease specialist, 33.8% of the cases in which no infection was confirmed, had a procalcitonin value >1microg/L and 14.9% of the cases with confirmed infection had procalcitonin levels <0.25 microg/L. The ability of procalcitonin to differentiate between certain or probable infection and possible or no infection, upon initiation of antibiotic treatment was low, as confirmed by the receiving operating curve analysis (area under the curve = 0.69). Finally, procalcitonin did not help improve concordance between the diagnostic confidence of the infectious-disease specialist and the ICU physician. CONCLUSIONS: : Procalcitonin measuring for the initiation of antimicrobials did not appear to be helpful in a strategy aiming at decreasing the antibiotic consumption in intensive care unit patients. [less ▲]Detailed reference viewed: 62 (6 ULg)
Le débit de filtration glomérulaire est-il un déterminant de la concentration plasmatique du NGAL aux soins intensifs ?
DELANAYE, Pierre ; ; et al
Poster (2012)Detailed reference viewed: 23 (4 ULg)
Detection of decreased glomerular filtration rate in intensive care units: interest of cystatin C
DELANAYE, Pierre ; CAVALIER, Etienne ; et al
Poster (2012)Detailed reference viewed: 18 (9 ULg)