References of "Damas, Pierre"
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See detailCytokines et nouveaux marqueurs inflammatoires
Chapelle, Jean-Paul ULg; Geenen, Vincent ULg; Malaise, Michel ULg et al

Conference (1999, March 13)

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See detailConsensus statement on the treatment of septic shock
Spapen, H.; Damas, Pierre ULg; D'Orio, Vincenzo ULg et al

in Acta Clinica Belgica (1999), 54(5), 256-262

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See detailAcute respiratory distress syndrome: 30 years later
Lesur, O.; Berthiaume, Y.; Blaise, G. et al

in Canadian Respiratory Journal : Journal of the Canadian Thoracic Society (1999), 6(1), 71-86

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See detailNew evaluation therapies for sepsis.
Deby; Damas, Pierre ULg; Lamy, Maurice ULg

in Current Opinion in Anaesthesiology (1999), 12(2), 121-7

This article presents an analysis of the literature of the last 2 years on the treatment of sepsis and septic shock. It appears that most of the antimediator therapies applied in phase II or III clinical ... [more ▼]

This article presents an analysis of the literature of the last 2 years on the treatment of sepsis and septic shock. It appears that most of the antimediator therapies applied in phase II or III clinical trials yielded disappointing results. But, many other therapeutic approaches are proposed or are ongoing, and many papers report critical analysis of the reasons for the lack of success of past clinical trials. [less ▲]

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See detailTransplantation combinée du foie et du coeur chez un patient souffrant de thalassémie majeure
Detry, Olivier ULg; Defechereux, Thierry ULg; Honore, Pierre ULg et al

in Médecine & Chirurgie Digestives (1999), 28(3), 109-110

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See detailA propos des relations entre inflammation et stress
Damas, Jacques ULg; Damas, Pierre ULg

in Revue Médicale de Liège (1999), 54(9), 751-758

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See detailSepsis and Serum Cytokine Concentrations
Damas, Pierre ULg; Canivet, Jean-Luc ULg; de Groote, Donat et al

in Critical Care Medicine (1997), 25(3), 405-12

OBJECTIVE: To look for relationships between the classification of sepsis and plasma cytokine concentrations. DESIGN: Prospective, consecutive entry study of patients meeting severe sepsis criteria and ... [more ▼]

OBJECTIVE: To look for relationships between the classification of sepsis and plasma cytokine concentrations. DESIGN: Prospective, consecutive entry study of patients meeting severe sepsis criteria and having bacteriologically documented infections. SETTING: University hospital, surgical intensive care unit. PATIENTS: Fifty consecutive patients developing severe sepsis or septic shock between December 1991 and December 1993. MEASUREMENTS AND MAIN RESULTS: Concentrations of tumor necrosis factor, interleukin (IL)-6, IL-8, and leukemia inhibitory factor were measured by immunoradiometric assay in the plasma of patients as soon as they developed severe sepsis or septic shock. Septic shock patients were divided into three groups in a blinded fashion (i.e., without knowing the results of the concentrations of cytokines), according to the presence of sustained hyperlactacidemia and to the rapidity of the onset of sepsis. Peak concentrations of all cytokines were statistically different between severe sepsis and septic shock patients. This finding was almost exclusively due to the data from patients with rapid onset of septic shock, who demonstrated very high but transient cytokine concentrations. Septic shock patients may thus have different profiles in the time course of their cytokine concentrations. The transient, high peak concentrations of cytokines were also related to transient leukopenia. Among the cytokines measured, IL-8 appeared to be the one that correlated best with lactacidemia, the presence of disseminated intravascular coagulation, severe hypoxemia, the Acute Physiology and Chronic Health Evaluation II score, and mortality rate. CONCLUSIONS: According to the profiles of the cytokines, septic shock patients do not represent a homogeneous population. These profiles should be described in order to distinguish between patients, and the profiles may be useful to identify those patients susceptible to new therapies. [less ▲]

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See detailTransplantation combinée du foie et du coeur chez un patient souffrant de thalassémie majeure
Detry, Olivier ULg; Defechereux, Thierry ULg; Honore, Pierre ULg et al

in Revue Médicale de Liège (1997), 52(8), 532-4

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See detailComparative evaluation of five hygroscopic condenser humidifiers during short-term postoperative mechanical ventilation
Sottiaux, Thierry; Meurice, F.; Mignolet, Ghislaine ULg et al

in Acta Anaesthesiologica Italica & Anaesthesia and Intensive Care in Italy (1997), 48(1-2), 59-68

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See detailScreening and characterization of specific anti-lipopolysaccharide antibodies in Belgian blood donors by enzyme-linked immunosorbent assays
Nys, Monique ULg; Laub, R.; Damas, Pierre ULg et al

in European Journal of Clinical Investigation (1996), 26(12), 1134-1142

The goal of this project was to find and collect high concentrations of endotoxin-specific antibodies for therapeutic IgG- or IgM-enriched preparations. Various enzyme-linked immunosorbent assays (ELISAs ... [more ▼]

The goal of this project was to find and collect high concentrations of endotoxin-specific antibodies for therapeutic IgG- or IgM-enriched preparations. Various enzyme-linked immunosorbent assays (ELISAs) were developed to perform longitudinal studies of the serological response to a large panel of smooth and rough purified lipopolysaccharide (LPS) extracts in a population of healthy blood donors. To accomplish this, 1612 human serum samples from volunteer blood donors collected by seven different blood banks in Belgium were screened and specific IgM and IgG activities were measured. Approximately 17% of the donors had anti-LPS concentrations higher than 40 mg L-1. Of these, 10.9% had anti-smooth LPS antibodies, 3.7% had anti-rough LPS antibodies and 2.8% were found to be positive towards both types of LPS. The mean anti-LPS antibody concentration was 8 mg L-1 for rough LPS and 14 mg L-1 for smooth LPS. Age- and sex-related distributions of the activities indicated that the greatest prevalence of high anti-LPS concentration was in women aged 40-49 years and in men older than 60 years. Differential absorption experiments showed that the pooled serum of selected blood donors contained a mixture of specific and cross-reacting antibodies. We detected predominantly anti-LPS activities due to the IgG1 and IgG2 subclasses. The range of specificities to different LPS was increased by the pooling of selected sera. It was concluded that pools of naturally occurring specific anti-LPS immunoglobulin antibodies may be obtained in Belgium by screening blood donors using ELISAs that we have developed. [less ▲]

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See detailLes fluoroquinolones
Damas, Pierre ULg

in Revue Médicale de Liège (1996), 51(1), 50-52

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See detailLes morphinomimétiques en réanimation
Lamy, Maurice ULg; Joris, Jean ULg; Damas, Pierre ULg et al

in Revue Janssen-Cilag (1996)

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See detailUn cas d'hyponatrémie sévère sous administration de pimozide (Orap)
LECLERCQ, Paul; Canivet, Jean-Luc; Damas, Pierre ULg et al

in Revue Médicale de Liège (1995), 50(4), 151-152

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See detailOpioids in intensive care
Lamy, Maurice ULg; Joris, Jean ULg; Damas, Pierre ULg et al

in Lawin, P.; Von Loewenich, V.; Schuster, H.-P. (Eds.) et al Intensivmedizin notfallmedizin anästhesiologie (1995)

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See detailInhaled nitric oxide for hemodynamic support after postpneumectomy ARDS
Chiche, Jean-Daniel; Canivet, Jean-Luc ULg; Damas, Pierre ULg et al

in Intensive Care Medicine (1995), 21(8), 675-678

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