References of "Daly, Adrian"
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See detailHypercalcemia treated by sunitinib
LOLY, Jean-Philippe ULg; VALDES SOCIN, Hernan Gonzalo ULg; Daly, Adrian ULg et al

in 23rd meeting of the Belgian Endocrine Society - Abstract book (2013, October 19)

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See detailLe gigantisme : Les résultats d'une étude clinique et génétique internationale
Rostomyan, Liliya ULg; Daly, Adrian ULg; Lila, A et al

in Annales d'Endocrinologie (2013, October), 74

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See detailCoexistence entre adénom hypophysaire et phéochromocytome - présentation de cas
Rostomyan, Liliya ULg; Potorac, Iulia ULg; Filipponi, S et al

in Annales d'Endocrinologie (2013, October), 74

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See detailFIPA : étude clinique et génétique à l'Hôpital "King Edward Memorial", Bombay (Mumbai) Inde
Bothra, N; Daly, Adrian ULg; CASTERMANS, Emilie ULg et al

in Annales d'Endocrinologie (2013, October), 74

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See detailCharacteristics of patients with pituitary gigantism : results of an international study
Rostomyan, Liliya ULg; Daly, Adrian ULg; Tichomirowa, M et al

in Endocrine abstracts - 15th European Congress of Endocrinology (2013, May)

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See detailReceptor expression in craniopharyngiomas causing tumor growth in pregnancy : case report and review of the literature
Tome, Monica; VROONEN, Laurent ULg; THIRY, Albert ULg et al

in Endocrine Abstracts - 15th European Congress of Endocrinology (2013, May)

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See detailFamilial Isolated Pituitary Adenomas (FIPA) and the Pituitary Adenoma Predisposition due to Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene.
BECKERS, Albert ULg; Aaltonen, Lauri A.; Daly, Adrian ULg et al

in Endocrine Reviews (2013)

Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their ... [more ▼]

Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their management involves neurosurgery, biological therapies, and radiotherapy. Early diagnosis of pituitary tumors while they are smaller may help increase cure rates. Few genetic predictors of pituitary adenoma development exist. Recent years have seen two separate, complimentary advances in inherited pituitary tumor research. The clinical condition of familial isolated pituitary adenomas (FIPA) has been described, which encompasses the familial occurrence of isolated pituitary adenomas outside of the setting of syndromic conditions like multiple endocrine neoplasia type 1 and Carney complex. FIPA families comprise approximately 2% of pituitary adenomas and represent a clinical entity with homogeneous or heterogeneous pituitary adenoma types occurring within the same kindred. The aryl hydrocarbon receptor interacting protein (AIP) gene has been identified as causing a pituitary adenoma predisposition of variable penetrance that accounts for 20% of FIPA families. Germline AIP mutations have been shown to associate with the occurrence of large pituitary adenomas that occur at a young age, predominantly in children/adolescents and young adults. AIP mutations are usually associated with somatotropinomas, but prolactinomas, nonfunctioning pituitary adenomas, Cushing disease, and other infrequent clinical adenoma types can also occur. Gigantism is a particular feature of AIP mutations and occurs in more than one third of affected somatotropinoma patients. Study of pituitary adenoma patients with AIP mutations has demonstrated that these cases raise clinical challenges to successful treatment. Extensive research on the biology of AIP and new advances in mouse Aip knockout models demonstrate multiple pathways by which AIP may contribute to tumorigenesis. This review assesses the current clinical and therapeutic characteristics of more than 200 FIPA families and addresses research findings among AIP mutation-bearing patients in different populations with pituitary adenomas. [less ▲]

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See detailPrise en charge des prolactinomes
VROONEN, Laurent ULg; Daly, Adrian ULg; Beckers, Albert ULg

in Revue Médicale Suisse (2013), 9

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See detailThe clinical and genetic characteristics of patients with gigantism
Rostomyan, Liliya ULg; Daly, Adrian ULg; Tichomirowa, M et al

in Symposium "Perspectives in Endocrinology" - Congresses Highlights 2012: ECE Firenze, ENDO Houston, ESPE Leipzig, SFE Toulouse, IWMEN Liège (2013)

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See detailSomatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations
Jaffrain-Réa, ML; Rotondi, S; Turchi, A et al

in Endocrine-Related Cancer (2013), 20

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See detailFamilial Pituitary Adenomas : An overview
Vasilev, V; Daly, Adrian ULg; Beckers, Albert ULg

in Hayat, MA (Ed.) Tumors of the Central nervous system (2013)

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See detailGenetic analysis in young patients with sporadic pituitary macroadenomas:Beside AIP don't forget MEN1 genetic analysis.
Cuny, Thomas; Pertuit, Morgane; Sahnoun-Fathallah, Mouna et al

in European Journal of Endocrinology (2013)

CONTEXT: germline mutations in the AIP gene have been identified in young patients (age </= 30 years old) with sporadic pituitary macroadenomas. Otherwise, there are few data concerning the prevalence of ... [more ▼]

CONTEXT: germline mutations in the AIP gene have been identified in young patients (age </= 30 years old) with sporadic pituitary macroadenomas. Otherwise, there are few data concerning the prevalence of MEN1 mutations in such population. OBJECTIVE: We assessed the prevalence of both AIP and MEN1 genetic abnormalities (mutations and large gene deletions) in young patients (age </= 30 years old) diagnosed with sporadic and isolated macroadenoma, without hypercalcemia and/or MEN1-associated lesions. DESIGN: The entire coding sequences of AIP and MEN1 were screened for mutations. In cases of negative sequencing screening, multiplex ligation-dependent probe amplification was performed for the detection of large genetic deletions. PATIENTS AND SETTINGS: 174 patients from Endocrinology Departments of 15 French University Hospital Centers were eligible for this study. RESULTS: 21/174(12%) patients had AIP (n=15, 8.6%) or MEN1 (n=6, 3.4%) mutations. In pediatric patients (age </= 18 years old), AIP/MEN1 mutation frequency reached nearly 22% (n=10/46). AIPmut and MEN1mut were respectively identified in 8/79 (10.1%) and 1/79 (1.2%) somatotropinoma patients; they each accounted for 4/74 (5.4%) prolactinoma patients with mutations. Half of patients (n=3/6) with gigantism displayed mutations in AIP. Interestingly, 4/12 (33%) patients with non-secreting adenomas bore either AIP or MEN1 mutations, whereas none of the 8 corticotroph-adenomas and a single thyrotropinoma case had mutations. No large gene deletions were observed in sequencing-negative patients. CONCLUSION: mutations in MEN1 can be of significance in young patients with sporadic isolated pituitary macroadenomas, particularly prolactinomas, and together with AIP, we suggest genetic analysis of MEN1 in such population. [less ▲]

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See detailThe role of tyrosin kinase inhibitors in a MEN2B patient with metastatic medullary thyroid carcinoma
Tome, M; Tomas, M-H; VROONEN, Laurent ULg et al

in Symposium "Perspectives in Endocrinology" - Congresses Highlights 2012: ECE Firenze, ENDO Houston, ESPE Leipzig, SFE Toulouse, IWMEN Liège (2013)

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See detailThe coexistence of a pituitary adenoma and pheochromocytoma (a case report)
Filipponi, S; Rostomyan, Liliya ULg; VROONEN, Laurent ULg et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

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See detailThe clinical and genetic characteristics of patients with gigantism
Rostomyan, Liliya ULg; Daly, Adrian ULg; Tichomirova, M et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

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See detailErythropoiesis in acromegaly : effect of GH or IGF-1 ? Data from the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal für Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3), 45

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See detailAge, GH and tumor size : the triangular relation in acromegaly. Data from the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal für Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3), 43

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See detailSeguimiento prospectivo ecocardiografico de 104 pacientes con enffermedades endocrinologicas tratados con cabergolina
Daly, Adrian ULg; VROONEN, Laurent ULg; Lancellotti, Patrizio ULg et al

in Abstract book - 54 Congreso Sociedad Espanola de Endocrinologia y nutrition (2012, May 23)

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See detailCaracteristicas de prolactinomas resisitentes a dosis estandar de cabergolina : un estudio multicentrico en 92 pacientes
Beckers, Albert ULg; Jaffrain-Réa, ML; VROONEN, Laurent ULg et al

in Abstract book - 54 Congreso Sociedad Espanola de Endocrinologia y nutrition (2012, May 23)

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See detailEl sindrome tiro-gastrico : screening en 410 pacientes atendidos pro patologia tiroidea
Tome, M; VALDES SOCIN, Hernan Gonzalo ULg; Auriemma, R et al

in Abstract book - 54 Congreso Sociedad Espanola de Endocrinologia y nutrition (2012, May 23)

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