References of "DELANAYE, Pierre"
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See detailUrinary NGAL: Use of absolute value or ratio to creatinine?
Cavalier, Etienne ULg; Bekaert, Anne-Catherine ULg; Legrand, Delphine ULg et al

in Acta Clinica Belgica (2010), 65-3

Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a promising marker for the detection of acute kidney injury. This marker has been proposed for urinary measurement. However ... [more ▼]

Introduction: Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a promising marker for the detection of acute kidney injury. This marker has been proposed for urinary measurement. However, in the literature, authors indistinctly use "absolute" value or NGAL to creatinine ratio. Up to now, there are no strong arguments favouring for one. This question is of importance as this marker is sensed to be used only on urine random samples. To find an answer to this very practical matter, one approach could be to compare biological CV(intra-individual variation) of the "absolute" and ratio results. [less ▲]

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See detailUrinary or plasma NGAL?: Analytical point of view
Cavalier, Etienne ULg; Saarbach, D.; Bekaert, Anne-Catherine ULg et al

in Acta Clinica Belgica (2010)

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See detailEstimation of the Stability of Parathyroid Hormone when Stored at -80°C for a Long Period
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Hubert, Philippe ULg et al

in Clinical Journal of the American Society of Nephrology (2009), 4(12), 1988-92

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See detailPrevalence of Chronic Kidney Disease in an Elderly Population: Impact of the Choice of the Equation Used for Estimating GFR
Mariat, Christophe; Cavalier, Etienne ULg; Maillard, Nicolas et al

Poster (2009, October)

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See detailDefining a "reference population": no easy task.
Cavalier, Etienne ULg; Delanaye, Pierre ULg

in Journal of Bone and Mineral Research (2009), 24(9), 1638

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See detailANALYTICAL PERFORMANCE OF THE C-TERMINAL FGF-23 (IMMUTOPICS)
Cavalier, Etienne ULg; Rozet, Eric ULg; Carlisi, Ignazia ULg et al

in Clinical Chemistry & Laboratory Medicine (2009, June), 47(M-A032),

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See detailDétection et estimation du niveau de la maladie rénale chronique
Delanaye, Pierre ULg; Cavalier, Etienne ULg; Mariat, Christophe et al

in Revue Médicale de Liège (2009), 64(2), 73-78

L’insuffisance rénale voit son incidence augmenter. Un diagnostic précoce et précis est requis. Le diagnostic de l’insuffisance rénale repose sur la mesure du débit de filtration glomérulaire. Les ... [more ▼]

L’insuffisance rénale voit son incidence augmenter. Un diagnostic précoce et précis est requis. Le diagnostic de l’insuffisance rénale repose sur la mesure du débit de filtration glomérulaire. Les formules basées sur la créatinine pour déterminer ce débit ont, par rapport à la créatinine sérique seule, apporté un plus mais, dans certaines situations, elles fournissent des résultats erronés. Le recours à la mesure de la clairance de créatinine sur une récolte d’urines de 24 heures peut être, dans ces situations où les caractéristiques anthropométriques sont hors normes, utile, mais avec toujours la difficulté d’une récolte minutée correcte. Si une mesure précise du débit de filtration glomérulaire est absolument nécessaire, une méthode de référence doit être choisie telle celle au chrome EDTA ou à l’iohexol. Enfin, tout bilan néphrologique doit, outre le dosage de créatinine, comprendre au moins une analyse d’urine à la tigette. Toute positivité pour la protéinurie lors de ce test mérite de réaliser un dosage quantitatif de la protéinurie soit sur 24 heures, soit plus aisément sur un échantillon [less ▲]

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See detailOn the demanding necessity of properly evaluating renal graft function in clinical trials.
Maillard, Nicolas; Alamartine, Eric; Berthoux, Francois et al

in Transplant International (2009), 22(2), 247-8

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See detailIndexing Glomerular Filtration Rate for Body Surface Area: Myth and Reality
DELANAYE, Pierre ULg; Mariat, Christophe; CAVALIER, Etienne ULg et al

in Krüger, E.; Hahn, K. (Eds.) Nephrology Dialysis Transplantation (2009)

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See detailEstimation of GFR by different creatinine- and cystatin-C-based equations in anorexia nervosa.
Delanaye, Pierre ULg; Cavalier, Etienne ULg; Radermecker, Régis ULg et al

in Clinical Nephrology (2009), 71(5), 482-91

Background: Patients with anorexia nervosa (AN) are at high risk of renal failure. Glomerular filtration rate (GFR) is overestimated when estimated by the creatinine-based equations. We have studied the ... [more ▼]

Background: Patients with anorexia nervosa (AN) are at high risk of renal failure. Glomerular filtration rate (GFR) is overestimated when estimated by the creatinine-based equations. We have studied the accuracy and precision of cystatin C-based equations. Method: 27 AN patients were included. GFR was measured with the chromium-51-ethylenediaminetetraacetate (51Cr-EDTA) method. We have compared the accuracy and precision of creatinine-based equations (MDRD and Cockcroft) with those of different new cystatin C-based equations. Results: The creatinine-based equations overestimate measured GFR, especially the MDRD study equation. All the cystatin C-based equations also overestimate measured GFR. The Cockcroft and Gault formula and the cystatin C-based equation published by Rule have the best accuracy and precision, but these last performances remain unsatisfactory. Conclusion: Both creatinine and cystatin C-based equations strongly overestimate measured in patients with AN. [less ▲]

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See detailAn unusual interference in parathormone assay caused by anti-goat IgG: a case report.
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Carlisi, Ignazia ULg et al

in Clinical Chemistry & Laboratory Medicine (2009), 47(1), 118

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See detailPrevalence of chronic kidney disease in Kinshasa: results of a pilot study from the Democratic Republic of Congo
Sumaili, Ernest K.; Krzesinski, Jean-Marie ULg; Zinga, Chantal V. et al

in Nephrology Dialysis Transplantation (2009), 24(1), 117-122

Abstract Background. The burden of chronic kidney disease (CKD) in sub-Saharan Africa is unknown. The aim of this study was to investigate the prevalence and the risk factors associated with CKD in ... [more ▼]

Abstract Background. The burden of chronic kidney disease (CKD) in sub-Saharan Africa is unknown. The aim of this study was to investigate the prevalence and the risk factors associated with CKD in Kinshasa, the capital of the Democratic Republic of Congo (DRC). Methods. In a cross-sectional study, 503 adult residents in 10 of the 35 health zones of Kinshasa were studied in a randomly selected sample. Glomerular filtration rate was estimated using the simplified Modification of Diet in Renal Disease Study equation (eGFR) and compared with the Cockcroft–Gault equation for creatinine clearance. The associations between health characteristics, indicators of kidney damage (proteinuria) and kidney function (<60 ml/min/1.73 m2) were examined. Results. The prevalence of all stages of CKD according to K/DOQI guidelines was 12.4% [95% confidence interval (CI), 11.0–15.1%]. By stage, 2% had stage 1 (proteinuria with normal eGFR), 2.4% had stage 2 (proteinuria with an eGFR of 60–89 ml/min/1.73 m2), 7.8% had stage 3 (eGFR, 30–59 ml/min/1.73 m2) and 0.2% had stage 5 (eGFR < 15 ml/min/1.73 m2). Hypertension and age were independently associated with CKD stage 3. The prevalences of major non-communicable diseases considered in this study were 27.6% (95% CI, 25.7–31.3%) for hypertension, 11.7% (95% CI, 10.3–14.4%) for diabetes mellitus and 14.9% (95% CI, 13.3–17.9%) for obesity. Hypertension was also independently associated with proteinuria. Conclusion. More than 10% of the Kinshasa population exhibits signs of CKD, which is affecting adults in their productive years. Risk factors for CKD, including hypertension, diabetes and obesity, are increasing. These alarming data must guide current and future healthcare policies to meet the challenge raised by CKD in this city and hopefully in the whole country. [less ▲]

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