Le cas clinique du mois. La triade "classique" de présentation de certains cancers bronchiolo-alvéolaires mucineux.; de Leval, Laurence ; et alin Revue Médicale de Liège (2010), 65(11), 611-4 The case of a 59-year-old female complaining of cough of recent onset, abundant salty expectoration and lung condensation is presented. This "triad" constitutes a rare but nearly pathognomonic ... [more ▼] The case of a 59-year-old female complaining of cough of recent onset, abundant salty expectoration and lung condensation is presented. This "triad" constitutes a rare but nearly pathognomonic presentation of mucinous bronchioloalveolar carcinoma (BAC) of the lung. [less ▲] Detailed reference viewed: 25 (2 ULg) Valve aortique percutanéeERPICUM, Marie ; DEFRAIGNE, Jean ; LANCELLOTTI, Patrizio et alin Urgences & Accueil (2010), 11(40), 6-8 Transcatheter aortic valve implantation (TAVI) is increasingly performed and represents a relatively safe alternative treatment for high risk patients denied to surgical aortic valve replacement. TAVI is ... [more ▼] Transcatheter aortic valve implantation (TAVI) is increasingly performed and represents a relatively safe alternative treatment for high risk patients denied to surgical aortic valve replacement. TAVI is performed at the University Hospital of Liege since July 2008 with the Medtronic CoreValve Revalving® system by femoral or subclavian access. This paper exposed the technique of TAVI and the nursing care required after this procedure. [less ▲] Detailed reference viewed: 42 (10 ULg) Thrombolysis of occluded infra-inguinal bypass grafts: is it worthwhile?Bonhomme, Stéphanie ; Trotteur, Geneviève ; Van Damme, Hendrik et alin Acta Chirurgica Belgica (2010), 110(4), 445-50 BACKGROUND: Thrombosis of an infra-inguinal bypass graft often results in a limb-threatening ischemia. There is no consensus on the optimal management strategy. AIM OF THE STUDY: To analyse safety and ... [more ▼] BACKGROUND: Thrombosis of an infra-inguinal bypass graft often results in a limb-threatening ischemia. There is no consensus on the optimal management strategy. AIM OF THE STUDY: To analyse safety and efficacy of catheter-guided intra-arterial thrombolysis to re-open thrombosed infra-inguinal bypass grafts and to identify factors that influence graft patency and limb salvage rate after thrombolytic procedures. METHODS: A continuous cohort-study of 106 thrombolytic procedures between 1993 to 2008. RESULTS: Despite a high initial success rate (76%), the mid-term results are less convincing, with a 58% re-occlusion rate at 45 months follow-up. Thrombosed vein grafts, old (2 weeks or more) occlusions, poor run-off and failure to identify or rectify an underlying causative stenosis are determinant for a poor long-term outcome of thrombolytic procedures. COMMENTS : The outcome results of author's experience are consistent with literature reports. Thrombolysis of occluded infra-inguinal bypass grafts should be limited to selective cases (recent occlusion, prosthetic or vein graft in place since 1 year or more, critical limb ischemia). Despite its obvious advantages, the long-term outcome of thrombolytic procedures is deceiving. The inherent risk of hemorrhagic complications should also be taken in account at the decision making of treatment strategy. The question whether, in general, catheter-guided selective intra-arterial thrombolysis offers a significant advantage over operative revascularisation (thrombectomy or new bypass) remains unanswered. A more selective approach seems to favour thrombolysis as most appropriate strategy in the management of recent (< 2 weeks) thromboses of grafts in place since at least 1 year. [less ▲] Detailed reference viewed: 20 (1 ULg) Do we need a new carotid artery stenting trial?Van Damme, Hendrik ; Defraigne, Jean ![]() in Acta Chirurgica Belgica (2010), 110(4), 432-44 Four well-conducted carotid artery trials comparing carotid artery stenting with carotid artery endarterectomy (EVA-3S, SPACE, ICSS and CREST) could not demonstrate the superiority of carotid artery ... [more ▼] Four well-conducted carotid artery trials comparing carotid artery stenting with carotid artery endarterectomy (EVA-3S, SPACE, ICSS and CREST) could not demonstrate the superiority of carotid artery stenting (CAS) over carotid artery endarterectomy (CEA). There is at the moment no level-I evidence to support widespread use of endovascular management of carotid artery disease in routine practice. In order to shead some light on the continuing debate on the role of carotid artery stenting, the authors conducted a search in contemporary published literature concerning carotid artery stenting. This extensive literature review reveals a higher peri-procedural stroke-death rate after CAS and a higher cost. Two other events hamper the value of CAS: a higher late restenosis rate and a higher risk of micro-embolisation during the procedure, compared with CEA. The authors conclude that the prevailing overenthusiasm of interventionalists (vascular surgeons, radiologists, cardiologists) for carotid artery stenting is not justified. [less ▲] Detailed reference viewed: 6 (1 ULg) Markers of oxidative stress limited to increased risk of cardiovascular disease in chronic hemodialysis patientsPincemail, Joël ; Bovy, Christophe ; Chapelle, Jean-Paul et alin Free Radical Biology & Medicine (2001), 31(suppl), 345 Detailed reference viewed: 6 (1 ULg) Successful Bridge to Transplantation with Pierce Donachy (Thoratec) Ventricular Assist DeviceDEFRAIGNE, Jean ; DETRY, Olivier ; et alin Acta Chirurgica Belgica (1998), 98(2), 90-4 Biventricular assistance with the Thoratec ventricular assist device was performed in a 48-year-old man waiting heart transplantation since 6 months. Indication for circulatory support was considered ... [more ▼] Biventricular assistance with the Thoratec ventricular assist device was performed in a 48-year-old man waiting heart transplantation since 6 months. Indication for circulatory support was considered because of the development of progressive irreversible right heart failure with deterioration of the hepatic and renal functions. Orthotopic heart transplantation was performed after 13 days of circulatory support. No complications occurred during the assistance and in the posttransplant period. The patient was discharged on day 21 after transplantation. Five months after transplantation he is well and alive. [less ▲] Detailed reference viewed: 4 (0 ULg) Métastases ganglionnaires, hépatiques et osseuses d'un chemodectome carotidien. A propos d'un casDEFRAIGNE, Jean ; Limet, Raymond ![]() in Journal de Chirurgie (1997), 134(7-8), 336-9 A case of malignant carotid body tumor with nodal, hepatic and bone metastases is reported. Carotid body chemodectomas are slow-growing tumors which invade local structures. These tumors are usually ... [more ▼] A case of malignant carotid body tumor with nodal, hepatic and bone metastases is reported. Carotid body chemodectomas are slow-growing tumors which invade local structures. These tumors are usually benign but can occasionally produce local and distant metastases. Development of metastatic localizations is the only formal proof of malignancy as histology cannot distinguish between benign and malignant chemodectomas. Bilateral carotid arteriography gives the diagnosis. Surgery is the basis of treatment and should be performed early in the course to limit operative complications. Radiotherapy can be given as adjuvant treatment. [less ▲] Detailed reference viewed: 11 (0 ULg) La maladie de Buerger: aspects cliniques et pronostiquesVAN DAMME, Hendrik ; ; DEFRAIGNE, Jean et alin Revue Médicale de Liège (1997), 52(10), 675-82 Detailed reference viewed: 5 (0 ULg) Les traumatismes artériels thoraciques.SAKALIHASAN, Natzi ; DEFRAIGNE, Jean ; Limet, Raymond ![]() in Vaisseaux, Coeur, Poumons [=VCP] (1996), 1(3), 97-101 Detailed reference viewed: 6 (2 ULg) Successful Tricuspid Valve Replacement and Pulmonary Valvulotomy for Carcinoid Heart DiseaseDEFRAIGNE, Jean ; ; Soyeur, Daniel et alin Acta Chirurgica Belgica (1996), 96(4), 170-6 A case of successful tricuspid valve replacement with a mechanical prosthesis and pulmonary valvulotomy for carcinoid heart disease is reported. The patient was a 61 years old women. The primary tumor was ... [more ▼] A case of successful tricuspid valve replacement with a mechanical prosthesis and pulmonary valvulotomy for carcinoid heart disease is reported. The patient was a 61 years old women. The primary tumor was in the terminal ileum. Liver metastasis and carcinoid syndrome were present since 8 years. After cardiac surgery, the patient survived 38 months and late death was related to disseminated metastasis. Even in case of metastasis, carcinoid tumor is slow growing. Without cardiac operation for correction of valvular lesions, terminal symptoms and death may often be related to cardiac operation for correction of valvular lesions, terminal symptoms and death may often be related to cardiac failure rather than to tumoral growth. Thus, even in presence of metastasis, cardiac surgery may be mandatory to improve both quality of life and survival. [less ▲] Detailed reference viewed: 4 (0 ULg) Proximal Migration of Vena Caval Filters: Report of Two Cases with Operative RetrievalDEFRAIGNE, Jean ; ; et alin Annals of Vascular Surgery (1995), 9(6), 571-5 Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle ... [more ▼] Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle, and in the second one the filter was found in the pulmonary artery. Both filters were retrieved under cardiopulmonary bypass via an incision in the right atrium and the pulmonary artery, respectively. These two observations underscore the risk of increased unwarranted indications and consequent higher complication rates of vena caval filters. [less ▲] Detailed reference viewed: 12 (0 ULg) Mechanical Flow Obstruction after Heart Transplantation Diagnosed by TeeCANIVET, Jean-Luc ; DEFRAIGNE, Jean ; et alin Annals of Thoracic Surgery (1994), 58(3), 890-1 We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal ... [more ▼] We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal echocardiography. The mean transstenotic gradient was measured at 13 mm Hg. Because of the profound hemodynamic and multisystemic failure, no surgical correction was attempted. The postmortem examination confirmed the stenosis at the level of the left atrium. [less ▲] Detailed reference viewed: 8 (0 ULg) Association of Aortic Stenosis and Gastrointestinal Bleeding (Heyde's Syndrome). Report of Two Cases; DEFRAIGNE, Jean ; Limet, Raymond ![]() in Acta Chirurgica Belgica (1993), 93(1), 31-3 The association between aortic stenosis and digestive angiodysplasia has been described for the first time by Heyde in 1958. This entity is thus known as Heyde's syndrome. In many instances, the recurrent ... [more ▼] The association between aortic stenosis and digestive angiodysplasia has been described for the first time by Heyde in 1958. This entity is thus known as Heyde's syndrome. In many instances, the recurrent small intestinal bleeding originating from angiodysplasia stopped after aortic valve replacement. We report two cases of patients presenting with a recurrent small intestinal bleeding originating from digestive angiodysplasia and suffering from aortic stenosis. Diagnosis of both pathologies is well documented in both cases. The replacement of the aortic valve by a biologic prosthesis stopped the bleeding. Prior to aortic valve replacement, the two patients suffered severe recurrent blood loss from intestinal angiodysplasia. The treatment of aortic stenosis greatly favored both cardiac and general status. We recommend aortic valve replacement with a biologic prosthesis prior to intestinal resection in patients presenting with Heyde's syndrome. We stress on the fact that anticoagulants must be stopped in order to minimize the risk of further bleeding. [less ▲] Detailed reference viewed: 9 (0 ULg) In Vivo Free Radical Production after Cross-Clamping and Reperfusion of the Renal Artery in the RabbitDEFRAIGNE, Jean ; PINCEMAIL, Joël ; FRANSSEN, Colette et alin Cardiovascular Surgery (1993), 1(4), 343-9 Postischaemic reperfusion injury is often attributed to the generation of oxygenated free radicals which may subsequently promote lipid peroxidation in cell membranes. Electron paramagnetic resonance ... [more ▼] Postischaemic reperfusion injury is often attributed to the generation of oxygenated free radicals which may subsequently promote lipid peroxidation in cell membranes. Electron paramagnetic resonance spectroscopy in association with the spin trap molecule alpha-phenyl-N-tert-butyl-nitrone allowed direct confirmation of lipid free radical production after renal ischaemia-reperfusion in an in vivo rabbit model. A 60-min period of ischaemia followed by reperfusion caused free radical production twofold greater than after 15 min of ischaemia. Glutathione and alpha-tocopherol have been measured in renal tissue, as indirect markers of lipid peroxidation. After 15 min of ischaemia followed by 10 min of reperfusion, the mean(s.e.m.) glutathione content of the ischaemic kidney was slightly but significantly reduced by 11.9(2.5)% (P < 0.003). The content of alpha-tocopherol was unchanged. However, 10 min of reperfusion following 60 min of ischaemia led to significant decrease in mean(s.e.m.) content of both glutathione (30.4(3.7)%) (2.23(0.2) versus 3.14(0.18) mumol/g wet tissue, P < 0.001) and alpha-tocopherol (46.1(7.8)%) (0.57(0.10) versus 1.09(0.14) micrograms/g wet tissue, P < 0.001) when compared to the control kidney. Under these experimental conditions, desferrioxamine (15 mg/kg administered intravenously before inducing ischaemia), a drug known to limit free radical production, significantly limited the decrease of alpha-tocopherol to 20.8(6.4)% (0.83(0.08) versus 1.05(0.04) micrograms/g wet tissue, P < 0.05), but did not prevent glutathione consumption in the reperfused kidney. [less ▲] Detailed reference viewed: 6 (0 ULg) Right aortic arch with aberrant left subclavian artery. Report of two cases.SAKALIHASAN, Natzi ; DEFRAIGNE, Jean ; Limet, Raymond ![]() in Surgical & Radiologic Anatomy [=SRA] (1991), (13), 327-331 Detailed reference viewed: 6 (2 ULg) Transplantation cardiaque. Mise à jour à partir de notre expérienceDEFRAIGNE, Jean ; ; Limet, Raymond ![]() in Revue Médicale de Liège (1991), 46(6), 314-28 Detailed reference viewed: 4 (0 ULg) Cystic pneumatosis of the intestine associated with bromchoemphysema.SAKALIHASAN, Natzi ; DEFRAIGNE, Jean ; in Journal de Chirurgie (1990), (127), 359-60 Detailed reference viewed: 2 (0 ULg) |
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