References of "Croisier, Jean-Louis"
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See detailPlasma riche en plaquettes pour le traitements de lésions tendineuses
Kaux, Jean-François ULg; Drion, Pierre ULg; Croisier, Jean-Louis ULg et al

in Journal de Réadaptation Médicale (2015), 35(3), 181-191

Objectives: The restorative properties of platelets, through the local release of growth factors, are used in various medical areas. This article reviews fundamental and clinical research relating to ... [more ▼]

Objectives: The restorative properties of platelets, through the local release of growth factors, are used in various medical areas. This article reviews fundamental and clinical research relating to platelet-rich plasma applied to tendinous lesions. Materials and method: Articles in French and English, published between 1 January 2012 and 30 September 2014 dealing with PRP and tendons were searched for using the Medline and Scopus data bases. Results: Forty-seven articles were identified which addressed pre-clinical and clinical studies: 27 relating to in vitro and in vivo animal studies and 20 relating to human studies. Of these, 5 addressed lateral epicondylitis, 2 addressed rotator cuff tendinopathies, 10 dealt with patellar tendinopathies and 3 looked at Achilles tendinopathies. Conclusions: The majority of pre-clinical studies show that PRP stimulates the tendon's healing process. However, clinical series remain more controversial and level 1, controlled, randomised studies are still needed. [less ▲]

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See detailIdentification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Couffignal, Vincent et al

in Clinical physiology and functional imaging (2015), 35(5), 368-375

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]

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See detailSmall Heat Shock Proteins (sHSPs), specific markers of exercise-induced muscle damage
Hody, Stéphanie ULg; Simonet, Arnaud ULg; Lacrosse, Zoé ULg et al

Poster (2015, July 12)

Unaccustomed eccentric (ECC) exercise may cause exercise-induced muscle damage (EIMD) whereas repeating submaximal ECC sessions is known to prevent this damage. The present study aimed to better ... [more ▼]

Unaccustomed eccentric (ECC) exercise may cause exercise-induced muscle damage (EIMD) whereas repeating submaximal ECC sessions is known to prevent this damage. The present study aimed to better understand the molecular mechanisms underlying EIMD and subsequent adaptation. C57BL adult mice were submitted to different treadmill running protocols: IEE (intense ECC exercise), ET (ECC training), CT (concentric training), LT (level training), ET+IEE, CT+IEE. A 2D-DIGE proteomic analysis on mouse quadriceps muscles revealed that HSP25 and alpha-crystallin B chain were significantly more abundant in IEE, CT+IEE, ET+IEE and ET groups compared to unexercised mice. Interestingly, immunofluorescence analysis highlighted that all damaged fibers also showed positive staining for sHSPs. In contrast, sHSPs+ fibers are not necessarily damaged, suggesting that the sHSPs response precedes increased sarcolemma permeability. Our data demonstrate that ECC exercise specifically increases sHSPs expression which may represent an early marker of damage and/or adaptation of the muscle fibers to ECC contraction. [less ▲]

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See detailBiomechanical Analysis of Abdominal Injury in Tennis Serves. A Case Report
Tubez, François ULg; Forthomme, Bénédicte ULg; Croisier, Jean-Louis ULg et al

in Journal of Sports Science & Medicine (2015), 14

The serve is an important stroke in any high level tennis game. A well-mastered serve is a substantial advantage for players. However, because of its repeatability and its intensity, this stroke is ... [more ▼]

The serve is an important stroke in any high level tennis game. A well-mastered serve is a substantial advantage for players. However, because of its repeatability and its intensity, this stroke is potentially deleterious for upper limbs, lower limbs and trunk. The trunk is a vital link in the production and transfer of energy from the lower limbs to the upper limbs; therefore, kin-ematic disorder could be a potential source of risk for trunk injury in tennis. This research studies the case of a professional tennis player who has suffered from a medical tear on the left rectus abdominis muscle after tennis serve. The goal of the study is to understand whether the injury could be explained by an inappropriate technique. For this purpose, we analyzed in three dimensions the kinematic and kinetic aspects of the serve. We also performed isokinetic tests of the player’s knees. We then compared the player to five other professional players as refer-ence. We observed a possible deficit of energy transfer because of an important anterior pelvis tilt. Some compensation made by the player during the serve could be a possible higher abdominal contraction and a larger shoulder external rotation. These partic-ularities could induce an abdominal overwork that could explain the first injury and may provoke further injuries. [less ▲]

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See detailEffect of a stretching program on overhead athletes with a stiff and painful shoulder
Schwartz, Cédric ULg; Croisier, Jean-Louis ULg; Bruls, Olivier ULg et al

Conference (2015, July 01)

Overhead athletes are more at risk of suffering shoulder injuries or/and developing shoulder pain. Stretching programs have been shown to successfully reduce pain for this population. However no study has ... [more ▼]

Overhead athletes are more at risk of suffering shoulder injuries or/and developing shoulder pain. Stretching programs have been shown to successfully reduce pain for this population. However no study has provided a global overview of the effects of stretching. The present study evaluated the evolution of the pain, the strength of the shoulder muscles, potential instabilities or lesion of the shoulder as well as the 3D scapular kinematics of 10 overhead athletes having a painful and stiff dominant shoulder. Our results show a significant decrease of the pain and of the positive impingement syndrome tests. The kinematics of the scapula reveals a more upward rotation of the scapula after the stretching, which may reduce the risk of sub-acromial conflicts. The strength of the internal and external rotators of the shoulder is not modified by the program. [less ▲]

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See detailHow biomechanical analysis may help to identify abdominal injury causes in high level tennis
Tubez, François ULg; Forthomme, Bénédicte ULg; Croisier, Jean-Louis ULg et al

Conference (2015, July)

This research studies the case of a professional tennis player who has suffered from a medical tear on the left rectus abdominis muscle after a tennis serve. The goal of the study is to understand whether ... [more ▼]

This research studies the case of a professional tennis player who has suffered from a medical tear on the left rectus abdominis muscle after a tennis serve. The goal of the study is to understand whether the injury could be explained by an inappropriate technique. For this purpose, we analyzed the three dimensions kinematic and kinetic of the serve. We also performed isokinetic tests of the knees. We compared the player to five other professional players. We observed a possible deficit of energy transfer because of an important anterior pelvis tilt. Some compensations of the player during serve could be a possible higher abdominal contraction and a larger shoulder external rotation. These particularities could induce an abdominal overwork that would explain the first injury and may provoke a new injury. [less ▲]

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See detailOne-year follow-up of platelet-rich plasma infiltration to treat chronic proximal patellar tendinopathies
Kaux, Jean-François ULg; Bruyère, Olivier ULg; Croisier, Jean-Louis ULg et al

in Acta Orthopaedica Belgica (2015), 81(2), 251-256

Infiltration of Platelet-Rich Plasma (PRP) may be considered as a recent therapeutic option for chronic tendinopathies. The aim of this study is to evaluate the clinical status and the return to sports ... [more ▼]

Infiltration of Platelet-Rich Plasma (PRP) may be considered as a recent therapeutic option for chronic tendinopathies. The aim of this study is to evaluate the clinical status and the return to sports activities in patients with chronic proximal patellar tendinopathies. Twenty subjects with chronic proximal patellar tendinopathy benefited from 1 infiltration of PRP coupled with a standardized eccentric rehabilitation. The follow-up (up to 1 year) was assessed by means of a Visual Anologue Scale (VAS), the International Knee Documentation Committee (IKDC) form and the Victorian Institute of Sport Assessment (VISA-P) score. Moreover, subjects had to answer an information questionnaire concerning their life and sports activities. Seventy percents of the patients reported a favourable evolution with decrease of pain, and returned to sports activities. With time, VAS dropped significantly and both IKDC and VISA-P scores improved also significantly. This study confirms that a local injection of PRP coupled with a program of eccentric rehabilitation for treating a chronic jumper’s knee, improves pain symptoms and the functionaliti [less ▲]

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See detailNo interest for a second closely-timed infiltration of platelet-rich plasma (PRP) to treat jumper’s knees
Kaux, Jean-François ULg; CROISIER, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Radmann, A; Hedenborg, S; Tsolakidis, E (Eds.) 20th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS (2015, June)

Introduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to ... [more ▼]

Introduction: Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of jumper’s knee. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of 2 or 3 successive infiltrations. The aim of this study was to evaluate whether 2 infiltrations of PRP proves moreeffective than a single treatment. Methods: Twenty patients suffering from chronic jumper’s knee were enrolled into our prospective, randomized and comparative study of level 2, and split into two randomized groups (1 or 2 infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. Results: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups.Discussion: The comparison between 1 or 2 infiltrations of PRP did not reveal any difference between the 2 groups at short to mid term. A second closely-timed infiltration of PRP to treat jumper’s knees is not necessary to improve the efficacy of this treatment in the short term. References: Kaux JF, Croisier JL, Bruyere O, Rodriguez de la Cruz C, Forthomme B, Brabant G et al. One injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper’s knee. J Sports Med Phys Fitness. 2014 Jun 19. [Epub ahead of print]. Kaux JF, Croisier JL, Forthomme B, Le Goff C, Buhler F, Savanier C et al. Using platelet-rich plasma to treat jumper’s knees: exploring the effect of a second closely-timed infiltration. J Sci Med Sport. Submitted. Kaux JF, Bruyère O, Croisier JL, Forthomme N, Le Goff C, Rohr N et al. One-year follow-up of platelet-rich plasma infiltration to treat chronic upper patellar tendinopathies. Acta Orthop Belg. In press. [less ▲]

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See detailTendinopathies and platelet-rich plasma (PRP): from pre-clinical experiments to therapeutic use
KAUX, Jean-François ULg; Drion, Pierre ULg; Croisier, Jean-Louis ULg et al

in Journal of Stem Cell & Regenerative Medicine (2015), 11(1), 7-17

Objectives: The restorative properties of platelets, through the local release of growth factors, are used in various medical areas. This article reviews fundamental and clinical research relating to ... [more ▼]

Objectives: The restorative properties of platelets, through the local release of growth factors, are used in various medical areas. This article reviews fundamental and clinical research relating to platelet-rich plasma applied to tendinous lesions. Materials and method: Articles in French and English, published between 1 January 2012 and 31 December 2014 dealing with PRP and tendons were searched for using the Medline and Scopus data bases. Results: Forty-seven articles were identified which addressed pre-clinical and clinical studies: 27 relating to in vitro and in vivo animal studies and 20 relating to human studies. Of these, five addressed lateral epicondylitis, two addressed rotator cuff tendinopathies, ten dealt with patellar tendinopathies and three looked at Achilles tendinopathies. Conclusions: The majority of pre-clinical studies show that PRP stimulates the tendon's healing process. However, clinical series remain more controversial and level 1, controlled, randomised studies are still needed. [less ▲]

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See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone health: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (2015), 41(2), 317-325

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

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See detailConcordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptionmetry among elderly people: a cross-sectional study
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in BMC Musculoskeletal Disorders (2015), 16(1), 60-67

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical ... [more ▼]

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical practice. Bioelectrical impedance analysis (BIA) could provide a simpler, portative, and less expensive alternative. Because the body composition assessment by BIA is device-dependent, the aim of this study was to appraise the concordance between the specific bioelectrical impedance device InBody S10 and DXA for the body composition evaluation. METHODS: Body composition, included appendicular lean mass divided by height squared (ALM/ht2) was measured by DXA (Hologic QDR Discovery device) and by BIA (InBody S10 Biospace device). Agreement between tools was assessed by means of the Bland Altman method and reliability was determined using the IntraClass Coefficient (ICC). ICC was also computed to assess the reliability of the test-retest performed by the same operator or by two different ones. RESULTS: A total of 219 subjects were enrolled in this study (mean age: 43.7 +/- 19.1 years old, 51.6% of women). For the ALM/ht2, reliability of the test-retest of the BIA was high with an ICC of 0.89 (95%CI: 0.86-0.92) when performed by the same operator and an ICC of 0.77 (95%CI: 0.72-0.82) when performed by two different operators. Agreement between ALM/ht2 assessed by DXA and BIA was low (ICC = 0.37 (95%CI: 0.25-0.48)). Mean ALM/ht2 was 9.19 +/- 1.39 kg/m2 with BIA and 7.34 +/- 1.34 kg/m2 with DXA, (p < 0001). A formula developed using a multiple regression analysis, and taking into account muscle mass assessed by BIA, as well as sex and body mass index, explains 89% of the ALM/ht2 assessed by DXA. CONCLUSIONS: Although our results show that the measure of ALM/ht2 by BIA is reliable, the agreement between DXA and BIA is low. Indeed, BIA seems to overestimate ALM/ht2 compared to DXA and, consequently, it is important to use an adapted formula to obtain measurement of the appendicular lean mass by BIA close to that measured by DXA. [less ▲]

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See detailDevelopment and validation of an accelerometer-based method for quantifying gait events
Boutaayamou, Mohamed ULg; Schwartz, Cédric ULg; Stamatakis, Julien et al

in Medical Engineering & Physics (2015)

An original signal processing algorithm is presented to automatically extract, on a stride-by-stride basis, four consecutive fundamental events of walking, heel strike (HS), toe strike (TS), heel-off (HO ... [more ▼]

An original signal processing algorithm is presented to automatically extract, on a stride-by-stride basis, four consecutive fundamental events of walking, heel strike (HS), toe strike (TS), heel-off (HO), and toe-off (TO), from wireless accelerometers applied to the right and left foot. First, the signals recorded from heel and toe three-axis accelerometers are segmented providing heel and toe flat phases. Then, the four gait events are defined from these flat phases. The accelerometer-based event identification was validated in seven healthy volunteers and a total of 247 trials against reference data provided by a force plate, a kinematic 3D analysis system, and video camera. HS, TS, HO, and TO were detected with a temporal accuracy ± precision of 1.3 ms ± 7.2 ms, ‒4.2 ms ± 10.9 ms, ‒3.7 ms ± 14.5 ms, and ‒1.8 ms ± 11.8 ms, respectively, with the associated 95% confidence intervals ranging from ‒6.3 ms to 2.2 ms. It is concluded that the developed accelerometer-based method can accurately and precisely detect HS, TS, HO, and TO, and could thus be used for the ambulatory monitoring of gait features computed from these events when measured concurrently in both feet. [less ▲]

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See detailEpidemiological Review of Injuries in Rugby Union
Kaux, Jean-François ULg; Julia, Marc; Delvaux, François ULg et al

in Sports (2015), 3(1), 21-29

Rugby is a sport that is growing in popularity. A contact sport par excellence, it causes a significant number of injuries. In Rugby Union, there are 30 to 91 injuries per 1000 match hours. This ... [more ▼]

Rugby is a sport that is growing in popularity. A contact sport par excellence, it causes a significant number of injuries. In Rugby Union, there are 30 to 91 injuries per 1000 match hours. This epidemiological review of injuries incurred by rugby players mentions the position and type of injuries, the causes, time during the match and season in which they occur and the players’ positions as well as the length of players’ absences following the injury. [less ▲]

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See detailPhysical abilities of elderly nursing home residents: The SENIOR cohort
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; CROISIER, Jean-Louis ULg et al

in The Journal of Nursing Home Research Sciences (2015), 1

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See detailRelationship between isometric strength of six lower limb muscle groups and motor skills among nursing home residents
Buckinx, Fanny ULg; Croisier, Jean-Louis ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2015), 4(4), 184-7

Abstract: This research aimed to assess the correlation between isometric muscle strength of the lower limb and motor skills. This is a cross sectional study performed among volunteer nursing home ... [more ▼]

Abstract: This research aimed to assess the correlation between isometric muscle strength of the lower limb and motor skills. This is a cross sectional study performed among volunteer nursing home residents included in the SENIOR (Sample of Elderly Nursing home Individuals: an Observational Research) cohort. The present analysis focused on isometric muscle strength of 6 lower limb muscle groups (i.e. knee extensors, knee flexors, hip abductors, hip extensors, ankle flexors and ankle extensors), assessed using a validated hand-held dynamometer (i.e. the MicroFET2 device), and motor skills evaluated using the Tinetti test, the Timed Up and Go test, the Short Physical Performance Battery test (SPPB) and the walking speed. The relationship between all these parameters was tested by means of a multiple correlation, adjusted on age, sex and body mass index. 450 nursing home residents (69.8% of women) with a mean age of 83.1±9.4 years were included in this study. Our results showed a significant inverse correlation between lower limb muscle strength and the time required to perform the TUG test or gait speed, except for ankle flexors and ankle extensors. The relationship between the Tinetti test or the SPPB score, and lower limb muscle strength was significant, except for ankle flexors and ankle extensors. In conclusion, a positive association between lower limb muscle strength of the four main muscle groups and motor skills of the elderly nursing residents was found in this research. Therefore, special attention should be given to these muscle groups during rehabilitation programs. [less ▲]

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See detailContribution of a Trunk Accelerometer System to the Characterization of Gait in Patients With Mild-to-Moderate Parkinson’s Disease
Demonceau, Marie ULg; Donneau, Anne-Françoise ULg; CROISIER, Jean-Louis ULg et al

in IEEE Journal of Biomedical and Health Informatics (2015)

OBJECTIVE: Gait disturbances like shuffling and short steps are obvious at visual observation in patients with advanced Parkinson's disease (PD). However, quantitative methods are increasingly used to ... [more ▼]

OBJECTIVE: Gait disturbances like shuffling and short steps are obvious at visual observation in patients with advanced Parkinson's disease (PD). However, quantitative methods are increasingly used to evaluate the wide range of gait abnormalities that may occur over the disease course. The goal of this study was to test the ability of a trunk accelerometer system to quantify the effects of PD on several gait features when walking at self-selected speed. METHODS: We recruited 96 subjects split into three age-matched groups: 32 healthy controls (HC), 32 PD patients at Hoehn and Yahr stage < II (PD-1), and 32 patients at Hoehn & Yahr stage II-III (PD-2). The following outcomes were extracted from the signals of the tri-axial accelerometer worn on the lower back: stride length, cadence, regularity index, symmetry index and mechanical powers yielded in the cranial-caudal, antero-posterior and medial-lateral directions. Walking speed was measured using a stopwatch. RESULTS: beside other gait features, the PD-1 and the PD-2 groups showed significantly reduced stride length normalized to height (p<0.02) and symmetry index (p<0.009) in comparison to the HC. Regularity index was the only feature significantly decreased in the PD-2 group as compared with the two other groups (p<0.01). The clinical relevance of this finding was supported by significant correlations with mobility and gait scales (r is around -0.3; p<0.05). CONCLUSION: Gait quantified by a trunk accelerometer may provide clinically useful information for the screening and follow-up of PD patients. [less ▲]

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