References of "Crine, Michel"
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See detailInfluence of medium composition on oxygen transfer rate in animal cell culture
Toye, Dominique ULg; Galifi, A.; Salmon, Thierry ULg et al

in Canadian Journal of Chemical Engineering (2010), 88(4), 671-676

Experiments were conducted in a 0.25m diameter bubble column to investigate the effect of medium composition on oxygen transfer rate. Aqueous solutions, the composition of which mimics a mammalian cell ... [more ▼]

Experiments were conducted in a 0.25m diameter bubble column to investigate the effect of medium composition on oxygen transfer rate. Aqueous solutions, the composition of which mimics a mammalian cell culture medium, are used. The effect on oxygen transfer rate of additives used to protect cells against local hydrodynamic stresses induced by bubble coalescence and bursting is addressed, in the range of operating conditions (aeration rates) met in animal cell cultures. The mass transfer coefficient, the liquid viscosity and surface tension, and the bubble size distribution are measured as a function of liquid composition and of gas superficial velocity, allowing to decouple the effects of the different additive on kL and on a. [less ▲]

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See detailLiquid load point determination in a reactive distillation packing by x-ray tomography
Aferka, Saïd ULg; Viva, Aurora ULg; Brunazzi, Elisabetta et al

in Canadian Journal of Chemical Engineering (2010), 88(4), 611-617

In this paper, we report on the use of Xray tomography to determine the liquid load point in 0.1m diameter modular catalytic distillation packings KatapakSP11 and KatapakSP12. The liquid load point ... [more ▼]

In this paper, we report on the use of Xray tomography to determine the liquid load point in 0.1m diameter modular catalytic distillation packings KatapakSP11 and KatapakSP12. The liquid load point corresponds to the overall packed bed liquid load above which there is an increment in the liquid flowing outside the catalytic baskets and the catalytic baskets themselves are saturated with liquid. From tomographic images, we show that several factors affect the wetting and filling of catalytic baskets. The complex hybrid structure of catalytic packings influences the liquid distribution inside the elements. The liquid preferentially fills the external catalytic baskets because they receive the liquid not only from the packing element situated above but also from the wall wipers. Moreover, liquid holdup inside a catalytic basket section depends significantly on the vertical position in the packing element and on the position of the packing in the column packed bed. The counter–current gas flow speeds up the process of liquid filling of the baskets, also for low liquid loads. The nonuniform distribution of liquid in catalytic basket which is observed experimentally makes the identification of a unique liquid load point not straightforward. [less ▲]

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See detailComparison of hydrodynamic parameters obtained by 2D measurements in a flat rectangular column with X-ray radiography and data from literature on 3D columns
Calvo, Sébastien ULg; Beugre, Djomice Antoine ULg; Crine, Michel ULg et al

Poster (2010)

Hydrodynamic tests are performed in a flat rectangular column packed with two sheets of Mellapak 250 Y (Sulzer structured packing). Measurements are realized with a single phase liquid flow as well as ... [more ▼]

Hydrodynamic tests are performed in a flat rectangular column packed with two sheets of Mellapak 250 Y (Sulzer structured packing). Measurements are realized with a single phase liquid flow as well as with a gas-liquid counter-current flow. Hydrodynamic parameters are compared to experimental results obtained in 3D columns found in the literature, as well as to literature model predictions and to values computed using an in-house Lattice Boltzmann CFD simulation code. [less ▲]

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See detailX-ray CT study of the influence of liquid viscosity on fluid phase distribution in modular catalytic packings
Aferka, Saïd ULg; Viva, Aurora; Toye, Dominique ULg et al

in AIDIC Conference series (2010), 10

In the frame of the present study, the influence of liquid viscosity on liquid holdup distribution in a packed column equipped with the modular catalytic packing Katapak-SP 11 is measured. Water and an ... [more ▼]

In the frame of the present study, the influence of liquid viscosity on liquid holdup distribution in a packed column equipped with the modular catalytic packing Katapak-SP 11 is measured. Water and an aqueous solution of glycerine, the viscosity of which equals 10 cP, are used as feed liquids. The estimation of liquid holdup is of great interest due to its strong influence on pressure drop, on solid wetting and on heat and mass transfer coefficients. The experimental technique used is high energy X-ray tomography, which is a unique technique to visualize the local liquid distribution inside the complex structure of packings and to quantify the liquid holdup at different scales. [less ▲]

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See detailMeasurement of liquid hold-up in catalytic structured packings: comparison of different experimental techniques
Viva, Aurora ULg; Aferka, Saïd ULg; Toye, Dominique ULg et al

in de Haan, A. B.; Kooijman, H.; Gorak, A. (Eds.) Proceedings of 9th Distillation and Absorption Conference (DA2010), Eindhoven, Pays-Bas, 12-15 septembre 2010 (2010)

This paper presents the results of an experimental study carried out to examine liquid hold-up in 100 mm diameter catalytic structured packing Katapak-SP. Two versions of the packing have been ... [more ▼]

This paper presents the results of an experimental study carried out to examine liquid hold-up in 100 mm diameter catalytic structured packing Katapak-SP. Two versions of the packing have been investigated. Both global and local measurements were carried out on the very same packings, using water at ambient conditions as working liquid. To this scope, traditional methods like draining techniques were used to obtain global hold-up values. A non-intrusive high energy X-ray tomography was used for gathering information on local scale and study axial distribution of the liquid hold-up over the packed column, inside and outside the catalyst containing baskets. The total liquid hold-up of the catalytic packed bed was evaluated by averaging hold-up values obtained at different cross sections over the corresponding volume. Very good agreement was found between global values estimated with the different techniques. The experimental results are useful for supporting theoretical developments in hydrodynamic and mass transfer modeling. [less ▲]

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See detailLiquid hold-up measurement in Mellapak Plus 752Y packed bed using X-ray tomography
Aferka, Saïd ULg; Viva, Aurora ULg; Brunazzi, Elisabetta et al

in VCIPT (Ed.) Proceedings of 6th World Congress On Industrial Process Tomography (WCIPT6), Beijing, China, 6-9 Septembre 2010 (2010)

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See detailInfluence of the viscosity on liquid hold-up in modular catalytic packings
Aferka, Saïd ULg; Viva, Aurora ULg; Brunazzi, Elisabetta et al

Conference (2010)

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See detailInterfacial area measurement in a catalytic distillation packing using high energy x-ray CT
Aferka, Saïd ULg; Marchot, Pierre ULg; Crine, Michel ULg et al

in Chemical Engineering Science (2010), 65(1), 511-516

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on ... [more ▼]

In this paper, we report on the use of X-ray tomography to visualize and quantify the gas–liquid interfacial area in modular catalytic distillation packing elements. The calculation method is based on processing of tomographic images. It is validated by comparing specific surface area determined on dry packings (Mellapak™ 752Y and Katapak™ SP12) tomographic binary images (gas and solid) to values announced by manufacturers, based on geometrical considerations. These data agree fairly well. However, tomographic images show that the specific area is not distributed uniformly over the height of a packing element due to the presence of perforations in corrugated sheets and of wall wipers between the packing and the column wall. X-ray tomography is a unique technique to access to the spatial distribution of these geometrical details in a non-intrusive way. The method used to determine the specific surface area of dry packing is then applied to irrigated packing in order to determine the gas–liquid interfacial area. The axial distribution of the interfacial area is non-uniform and is correlated to the packing specific area. The maxima of the specific surface area correspond to the presence of wall wipers. The gas–liquid interfacial area averaged over the column length is determined. It increases logically with the liquid superficial velocity and slightly with the gas velocity. The effect of the gas velocity is however more pronounced when reaching loading point. [less ▲]

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See detailInfluence of operating conditions on the gaseous emissions related to urban residual sludge convective drying
Fraikin, Laurent ULg; Herbreteau, Benjamin; Chaucherie, Xavier et al

Poster (2010)

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See detailDevelopment of a compartment model based on CFD simulations for mixing description in bioreactors
Delafosse, Angélique ULg; Delvigne, Frank ULg; Collignon, Marie-Laure ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14(2), 517-522

Understanding and modelling the complex interactions between biological reaction and hydrodynamics is a key problem when dealing with bioprocesses. It is fundamental to be able to accurately predict the ... [more ▼]

Understanding and modelling the complex interactions between biological reaction and hydrodynamics is a key problem when dealing with bioprocesses. It is fundamental to be able to accurately predict the hydrodynamics behaviour of bioreactors of different size and its interaction with the biological reaction. CFD can provide detailed modelling about hydrodynamics and mixing. However, it is computationally intensive, especially when reactions are taken into account. Another way to predict hydrodynamics is the use of "Compartment" or "Multi-zone" model which are much less demanding in computation time than CFD. However, compartments and fluxes between them are often defined by considering global quantities not representative of the flow. To overcome the limitations of these two methods, a solution is to combine compartment modelling and CFD simulations. Therefore, the aim of this study is to develop a methodology in order to propose a compartment model based on CFD simulations of a bioreactor. The flow rate between two compartments can be easily computed from the velocity fields obtained by CFD. The difficulty lies in the definition of the zones in such a way they can be considered as perfectly mixed. The creation of the model compartments from CFD cells can be achieved manually or automatically. The manual zoning consists in aggregating CFD cells according to the user's wish. The automatic zoning defines compartments as regions within which the value of one or several properties are uniform with respect to a given tolerance. Both manual and automatic zoning methods have been developed and compared by simulating the mixing of an inert scalar. For the automatic zoning, several algorithms and different flow properties have been tested as criteria for the compartment creation. [less ▲]

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See detailQuality of mixing in a stirred bioreactor used for animal cells culture: heterogeneities in a lab scale bioreactor and evolution of mixing time with scale up
Collignon, Marie-Laure ULg; Dossin, Denis; Delafosse, Angélique ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2010), 14

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of ... [more ▼]

Animal cells are industrially cultivated inside stirred bioreactors to produce proteinic compounds. Due to the use of mild agitation conditions in order to limit mechanical constraints, the homogeneity of the culture medium can be far from perfect. This study has therefore two objectives. 1) the global characterization of the mixing via the mixing time 2) the local description of concentration fields. The mixing time is measured by conductimetry inside 20 L, 80 L, 600L tanks. The Grenville correlation is adjusted on these experimental measurements to improve the prediction of the mixing time during the scale-up of the process. The concentration fields are visualized by the Planar Laser Induced Fluorescence (P.L.I.F) technique in the 20 L tank. This part of the study is focused on the time evolution of the maximum value of the tracer concentration inside measurement planes and of the numerical distribution of theses concentration fields. [less ▲]

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See detailEffect of liming on the convective drying of urban residual sludges
Huron, Yoland; Salmon, Thierry ULg; Blandin, Gaëtan et al

in Asia-Pacific Journal of Chemical Engineering (2010), 5

Sludge liming is largely used in the wastewater industry. This operation, at first realized to stabilize sludge, has also proved to enhance dewatering and to improve the resulting cakes texture ... [more ▼]

Sludge liming is largely used in the wastewater industry. This operation, at first realized to stabilize sludge, has also proved to enhance dewatering and to improve the resulting cakes texture. Nevertheless, almost nothing is known about the impact of lime addition on sludge drying behavior. As drying can be considered as a necessary step after mechanical dewatering, it is crucial to evaluate the influence of the sludge pre-treatments on their drying kinetics. This study shows that both pre- and post-liming exert a positive effect on sludge convective drying behavior. The negative impact of sludge destructuring by pumping is also established. [less ▲]

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See detailConvective drying of gels: comparison between simulated and experimental moisture profiles obtained by X-ray microtomography
Escalona, Ivonne; Jomaa, Wahbi; Olivera-Fuentes, C. et al

in Drying Technology (2010), 28(5), 644-650

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See detailÉmissions gazeuses liées au séchage convectif de boues de station d’épuration
Fraikin, Laurent ULg; Herbreteau, Benjamin; Nicol, François et al

in SFGP (Ed.) Récents Progrès en Génie des Procédés - N°98 - A la croisée des sciences et des cultures pour relever les défis industriels du XXIème siècle - Actes du 12ème Congrès de la Société Française de Génie des Procédés, Marseille, France, 14-16 octobre 2009 (2009, October)

Detailed reference viewed: 64 (16 ULg)