References of "Crielaard, Jean-Michel"
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See detailIsokinetic evaluation of knee extensors and flexors in patients with unilateral symptomatic gonarthrosis
Henrotin, Yves ULg; Croisier, Jean-Louis ULg; Dumont, R. et al

in Isokinetics & Exercise Science (2000, March), 8

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See detailIsokinetic evaluation of hip strength muscle groups in unilateral lower limb amputees
Croisier, Jean-Louis ULg; Maertens De Noordhout, Benoît; Camus, Gérard et al

in Isokinetics & Exercise Science (2000, March), 8

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See detailModulation of human chondrocyte metabolism by recombinant human interferon.
Henrotin, Yves ULg; Zheng, S X; Labasse, A H et al

in Osteoarthritis and Cartilage (2000), 8(6), 474-82

OBJECTIVES: Interferon gamma (IFN gamma) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its implication in joint disease pathogenesis ... [more ▼]

OBJECTIVES: Interferon gamma (IFN gamma) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its implication in joint disease pathogenesis. In this study, we investigated the effects of IFN gamma on the production of cytokines (IL-6, IL-8, IL-10), prostaglandin E(2)(PGE(2)), proteoglycans (PG), nitric oxide (NO), interleukin-1 receptor antagonist (IL-1ra) and stromelysin by non-stimulated and IL-1 beta-treated human chondrocytes. The role played by NO in the responses of chondrocytes to IFN gamma was also examined by incubation of chondrocytes with N(G)-monomethyl-L-arginine (L-NMMA), a competitive inhibitor of NO synthase. METHODS: Enzymatically isolated human chondrocytes were cultured for 48 h in the absence or presence of IL-1 beta, IFN gamma or N(G)-monomethyl-L-arginine (L-NMMA) added solely or in combination. The productions of IL-6, IL-8, IL-10, IL-1ra and stromelysin were measured by enzyme amplified sensitivity immunoassays (EASIA). PG and PGE(2)were quantified by specific radioimmunoassays (RIA). Nitrite concentrations in the culture supernatants were determined by a spectrophotometric method based upon the Griess reaction. RESULTS: As expected, IL-1 beta highly stimulated NO, IL-6, IL-8, IL-10, IL-1ra, PGE(2)and stromelysin synthesis, but dramatically decreased PG production. NO, IL-6, IL-1ra and PGE(2)production by non-stimulated chondrocytes was dose-dependently increased by IFN gamma while PG production was inhibited. In the absence of IL-1 beta, IL-10 was undetectable in the culture supernatants. At the doses of 10 and 100 U/ml, IFN gamma markedly inhibited the constitutive and IL-1 beta-stimulated IL-8, IL-10 and stromelysin productions. Interestingly, IFN gamma synergized with IL-1 beta to increase NO, IL-6, IL-1ra and to depress PG production. As previously reported, the inhibition of NO synthesis by the competitive inhibitor L-NMMA led to enhancement of IL-6, IL-8 and PGE(2)production by IL-1 beta treated chondrocytes, but did not significantly modify IL-10, PG and MMP-3 productions. Inhibition of NO synthase significantly inhibited the stimulating effect of IFN gamma on IL-6 and IL-1ra but did not affect the inhibitory effect of IFN gamma on IL-8, PG or stromelysin production. CONCLUSIONS: These findings suggest that IFN gamma and IL-1 synergistically stimulate the production of IL-6, IL-1ra, NO and PGE(2)and inhibit PG synthesis. By contrast, IL-1 beta and IFN gamma have opposite effects on IL-8, IL-10 and stromelysin productions. These effects are not reversed by L-NMMA, suggesting that NO is not the principal mediator involved in responses of chondrocytes to IFN gamma. [less ▲]

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See detailBases scientifiques du traitement physique de la gonarthrose
Henrotin, Yves ULg; Croisier, Jean-Louis ULg; Reginster, Jean-Yves ULg et al

in KINE 2000 (2000), 11(4), 86-94

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See detailIsokinetic evaluation of knee extensors and flexors in patients with unilateral symptomatic gonarthrosis
Henrotin, Yves ULg; Croisier, Jean-Louis ULg; Dumont, R et al

in Annals of the Rheumatic Diseases (2000), 59(S1), 275

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See detailLe syndrome du canal lent
Zeevaert, Bernard; WANG, François-Charles ULg; CRIELAARD, Jean-Michel ULg

Conference (2000)

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See detailEvaluation isocinétique des muscles du genou au cours de la gonarthrose
Croisier, Jean-Louis ULg; Henrotin, Yves ULg; Dumont, Régine ULg et al

in Isocinétisme et personnes âgées (2000)

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See detailInsuffisance respiratoire et isocinétisme
Croisier, Jean-Louis ULg; Georis, Pierre ULg; Hac, S. et al

in Isocinétisme et personnes âgées (2000)

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See detailHamstring muscle tear with recurrent complaints: An isokinetic profile
Croisier, Jean-Louis ULg; Crielaard, Jean-Michel ULg

in Isokinetics & Exercise Science (2000), 8(3), 175-180

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See detailVérification de la validité du test kinésiologique de Meerseman par des mesures isocinétiques
Fernandez-Moreno, S.; Croisier, Jean-Louis ULg; Crielaard, Jean-Michel ULg et al

in Actes du XIIIème Colloque de l’association Internationale Francophone de Recherche Odontologique (2000)

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See detailL’isocinétisme au service du footballeur blessé
Crielaard, Jean-Michel ULg; Croisier, Jean-Louis ULg

in Actes du Colloque Médical : « Foot 2000 : entraînement optimal, risque minimal » (2000)

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See detailExercices excentriques appliqués au traitement des tendinites
Forthomme, Bénédicte ULg; Croisier, Jean-Louis ULg; Foidart-Dessalle, Marguerite ULg et al

in Actes du Congrès Eurokiné 1999 (1999, November)

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See detailPourquoi et comment effectuer un renforcement musculaire excentrique ?
Croisier, Jean-Louis ULg; Crielaard, Jean-Michel ULg

in Actes du Congrès Eurokiné 1999 (1999, November)

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See detailPotential effects of NSAID on myocellular enzyme leakage and delayed onset muscle soreness induced by isokinetic eccentric exercise
Croisier, Jean-Louis ULg; Camus, Gérard; Crielaard, Jean-Michel ULg

in Actes du XIXe Congrès National de la Société Française de Médecine du Sport (1999, October)

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See detailEffects of training on delayed onset muscle soreness following isokinetic eccentric exercise
Croisier, Jean-Louis ULg; Camus, Gérard; Ledent, M. et al

in Archives of Physiology & Biochemistry (1999, September), 107(suppl september 1999), 101

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See detailHuman Muscle Energetics During Voluntary and Electrically Induced Isometric Contractions as Measured by 31p Nmr Spectroscopy
Vanderthommen, Marc ULg; Gilles, R.; Carlier, Pierre ULg et al

in International Journal of Sports Medicine (1999), 20(5), 279-83

Electrical stimulation (ES) and voluntary contraction (VC) were compared in the quadriceps muscle of ten male volunteers. In both modes, a workload corresponding to 20% of maximal voluntary contraction ... [more ▼]

Electrical stimulation (ES) and voluntary contraction (VC) were compared in the quadriceps muscle of ten male volunteers. In both modes, a workload corresponding to 20% of maximal voluntary contraction was applied during 64 isometric contraction (5.5 s)-relaxation (5.5 s) cycles. The protocols were performed in a 1.5 T whole-body magnet. The Pi/PCr ratio and the intracellular pH (pHi) were monitored by 31P NMR spectroscopy during baseline, exercise and recovery periods, in a superficial region of the vastus medialis. During baseline, the Pi/PCr ratio (0.12 vs. 0.10) and the pHi (7.01 vs. 7.00) were comparable in both conditions. During exercise, the Pi/PCr ratio was higher (0.36 vs. 0.14) and the pHi was lower (6.85 vs. 7.07) during ES than during VC. For the same external work production, these results reflect a different metabolic solicitation in the ES quadriceps than in the VC ones. [less ▲]

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