References of "Collette, Fabienne"
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See detailCerebral metabolic correlates of four dementia scales in Alzheimer's disease
Salmon, Eric ULg; Lespagnard, Solange ULg; Marique, Patricia et al

in Journal of Neurology (2005), 252(3), 283-290

Different scales can be used to evaluate dementia severity in Alzheimers disease (AD). They do assess different cognitive or functional abilities, but their global scores are frequently in mutual ... [more ▼]

Different scales can be used to evaluate dementia severity in Alzheimers disease (AD). They do assess different cognitive or functional abilities, but their global scores are frequently in mutual correlation. Functional imaging provides an objective method for the staging of dementia severity. Positron emission tomography was used to assess the relationship between brain metabolism and four dementia scales that reflect a patients global cognitive abilities (mini mental state), caregivers evaluation of cognitive impairment (newly designed scale), daily living functioning (instrumental activities of daily living) and global dementia (clinical dementia rating). We wondered whether different clinical dementia scales would be related to severity of metabolic impairment in the same brain regions, and might reflect impairment of common cognitive processes. 225 patients with probable AD were recruited in a prospective multicentre European study. All clinical scales were related to brain metabolism in associative temporal, parietal or frontal areas. A factorial analysis demonstrated that all scales could be classified in a single factor. That factor was highly correlated to decrease of cerebral activity in bilateral parietal and temporal cortices, precuneus, and left middle frontal gyrus. This finding suggests that global scores for all scales provided similar information on the neural substrate of dementia severity. Capitalizing on the neuroimaging literature, dementia severity reflected by reduced metabolism in posterior and frontal associative areas in AD might be related to a decrease of controlled processes. [less ▲]

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See detailTime-of-day modulations of rCBF response in functional brain imaging studies: a meta-analysis
Schmidt, Christina; Dang Vu, Thanh; Orban, Pierre et al

in NeuroImage (2005), 26(Suppl. 1),

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See detailEXploration des processus inhibiteurs dans le vieillissement normal et la maladie d'Alzheimer
Collette, Fabienne ULg; Adam, Stéphane ULg; Hogge, Michaël et al

in Revue Neurologique (2005), 161(12), 467

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See detailTwo Aspects of Impaired Consciousness in Alzheimer's Disease
Salmon, Eric ULg; Ruby, Perrine; Perani, Daniela et al

in Progress in Brain Research (2005), 150(Boundaries of Consciousness: Neurobiology and Neuropathology), 287-98

Alzheimer's disease (AD) is a degenerative dementia characterized by different aspects of impaired consciousness. For example, there is a deficit of controlled processes that require conscious processing ... [more ▼]

Alzheimer's disease (AD) is a degenerative dementia characterized by different aspects of impaired consciousness. For example, there is a deficit of controlled processes that require conscious processing of information. Such an impairment is indexed by decreased performances at controlled cognitive tasks, and it is related to reduced brain metabolic activity in a network of frontal, posterior associative, and limbic regions. Another aspect of impaired consciousness is that AD patients show variable levels of anosognosia concerning their cognitive deficits. A discrepancy score between patient's and caregiver's assessment of cognitive functions is one of the most frequently used measures of anosognosia. A high discrepancy score has been related to impaired activity in the superior frontal sulcus and the parietal cortex in AD. Anosognosia for cognitive deficits in AD could be partly explained by impaired metabolism in parts of networks subserving self-referential processes (e.g., the superior frontal sulcus) and perspective-taking (e.g., the temporoparietal junction). We hypothesize that these patients are impaired in the ability to see themselves with a third-person perspective (i.e., being able to see themselves as other people see them). [less ▲]

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See detailLa mémoire de travail
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Gély-Nargeot, Marie-Christine; Ergis, Anne-Marie; Van der Linden, Martial (Eds.) Les troubles de la mémoire dans la maladie d'Alzheimer (2005)

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See detailExploration de l'administrateur central de la mémoire de travail au moyen de la tomographie par émission de positons (TEP)
Collette, Fabienne ULg

in Gueguen, B.; Chauvel, P.; Touchon, J. (Eds.) Neurophysiologie des mémoires (2005)

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See detailEvaluation de l’effet d’oubli induit à la récupération dans le vieillissement normal
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

Poster (2004, December 04)

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See detailStroop interference and negative priming in normal aging
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

Poster (2004, December 02)

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See detailAre spatial memories strengthened in the human hippocampus during slow wave sleep?
Peigneux, Philippe ULg; Laureys, Steven ULg; Fuchs, Sonia et al

in Neuron (2004), 44(3), 535-545

In rats, the firing sequences observed in hippocampal ensembles during spatial learning are replayed during subsequent sleep, suggesting a role for posttraining sleep periods in the offline processing of ... [more ▼]

In rats, the firing sequences observed in hippocampal ensembles during spatial learning are replayed during subsequent sleep, suggesting a role for posttraining sleep periods in the offline processing of spatial memories. Here, using regional cerebral blood flow measurements, we show that, in humans, hippocampal areas that are activated during route learning in a virtual town are likewise activated during subsequent slow wave sleep. Most importantly, we found that the amount of hippocampal activity expressed during slow wave sleep positively correlates with the improvement of performance in route retrieval on the next day. These findings suggest that learning-dependent modulation in hippocampal activity during human sleep reflects the offline processing of recent episodic and spatial memory traces, which eventually leads to the plastic changes underlying the subsequent improvement in performance. [less ▲]

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See detailDirected forgetting in normal aging: the role of processing speed
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

Poster (2004, June 25)

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See detailRetrieval-induced forgetting in normal aging
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

Poster (2004, May 05)

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See detailPréambule
Meulemans, Thierry ULg; Collette, Fabienne ULg; Van der Linden, Martial ULg

in Meulemans, Thierry; Collette, Fabienne; Van der Linden, Martial (Eds.) Neuropsychologie des fonctions exécutives (2004)

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See detailExploration des fonctions exécutives par imagerie cérébrale
Collette, Fabienne ULg

in Meulemans, Thierry; Collette, Fabienne; Van der Linden, Martial (Eds.) Neuropsychologie des fonctions exécutives (2004)

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See detailExecutive functions
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Morris, R. G.; Becker, J. T. (Eds.) The cognitive Neuropsychology of Alzheimer's disease (2004)

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See detailNeuropsychologie des fonctions exécutives
Meulemans, Thierry ULg; Collette, Fabienne ULg; Van der Linden, Martial ULg

Book published by Solal (2004)

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