References of "Clercx, Cécile"
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See detailPro- and antigelatinolytic activities in the serum and airways of cats with experimentally-induced asthma
Leemans, Jérôme ULg; Kirschvink; Clercx, Cécile ULg et al

in Proceedings : 25th Symposium of the Veterinary Comparative Respiratory Society (2007)

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See detailHigh resolution 16 row computed tomography examination of the canine thorax
De Busscher; Bolen, Géraldine ULg; Cavrenne et al

Poster (2007)

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See detailEffect of obesity on doxapram hydrochlorid-induced effects on whole body barometric plethysmography measurements in healthy Beagle dogs
Bolognin, M.; Bernaerts, Frederique ULg; Herpigny, F. et al

in 24th Symposium of the Veterinary Comarative Respiratory Society - Jena, Allemagne 8-10 octobre 2006 (2006, October 08)

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See detailInvestigation of airway reactivity by barometric whole body plethysmography in cats with spontaneous bronchial disease
Bernaerts, Frederique ULg; Merveille, Anne-Christine ULg; Bolognin, M. et al

in 24th Symposium of the Veterinary Comarative Respiratory Society - Jena, Allemagne 8-10 octobre 2006 (2006, October)

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See detailInvestigation of the effect of salbutamol and prenisolone on lung function test in healthy dogs with experimentally induced airway inflammation
Bolognin, M.; Talavera, J.; Bernaerts, Frederique ULg et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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See detailAbsence of bronchoprotective effects to a histamine challenge test of intravenous theophylline and salbutamol in healthy dogs
Talavera, J.; Bernaerts, Frederique ULg; Kirschvink, N. et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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See detailEffect of obesity in dogs on airway reactivity measured by barometric whole body plethysmography
Bernaerts, Frederique ULg; Bolognin, M.; Dehard, S. et al

in 16th ECVIM Meeting - Amsterdam - Nederlands - Septembre 2006 (2006, September)

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See detailA randomised double blinded placebo controlled study of spironolactone as adjunct to conventional congestive heart failure treatment in dogs: clinical, biochemical and neurohormonal parameters
Schuller, S.; Van Israel; Van Belle, S. et al

in 16th ECVIM Meeting - Amsterdam - Nederland - Septembre 2006 (2006, September)

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See detailA randomised double blinded placebo controlled study of spironolactone as adjunct to conventional congestive heart failure treatment in dogs: electrocardiographic, radiographic, echocardiographic and survival analysis
Van Israel, N.; Schuller, S.; Van Belle, S. et al

in 16th ECVIM Meeting - Amsterdam - Nederland - Septembre 2006 (2006, September)

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See detailSurgical treatment of canine nasal aspergillosis by rhinotomy combined with enilconazole infusion and oral itraconazole.
Claeys, Stéphanie ULg; Lefebvre, J.-B.; Schuller, S. et al

in Journal of Small Animal Practice (2006), 47(6), 320-4

OBJECTIVES: To evaluate the effectiveness of rhinotomy and surgical debridement associated with topical administration of 2 per cent enilconazole and oral itraconazole in dogs with severe or recurrent ... [more ▼]

OBJECTIVES: To evaluate the effectiveness of rhinotomy and surgical debridement associated with topical administration of 2 per cent enilconazole and oral itraconazole in dogs with severe or recurrent sinonasal aspergillosis. METHODS: A standard rhinotomy was performed on seven dogs. In the initial study, the bone flap was left attached cranially and replaced at the end of the procedure. In the main study group, the bone flap was discarded. Nasal passages were debrided and irrigated with enilconazole solution for one hour. Oral itraconazole was administered to four dogs for one month postoperatively. Follow-up rhinoscopy was performed in all dogs. RESULTS: All three dogs in the initial study had recurrence of the disease and two dogs had a second surgery to remove the flap. The main study group included four dogs in which the flap was initially removed, and the two dogs from the initial study that required a second surgery. At follow-up rhinoscopy, five dogs were free of aspergillus but had bacterial or inflammatory rhinitis and one dog had a small aspergilloma but was subsequently asymptomatic. Telephone follow-up revealed that four dogs were asymptomatic, one dog had intermittent sneezing and serous nasal discharge, and one dog had intermittent epistaxis. CLINICAL SIGNIFICANCE: Rhinotomy with removal of the flap combined with one-hour infusion of 2 per cent enilconazole and oral itraconazole resulted in satisfactory outcome in dogs with severe or recurrent aspergillosis. [less ▲]

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See detailDiagnosis of pharyngeal disorders in dogs: a retrospective study of 67 cases
Billen, Frédéric ULg; Day, M. J.; Clercx, Cécile ULg

in Journal of Small Animal Practice (2006), 47(3), 122-129

OBJECTIVES: To assess the frequency distribution of pharyngeal disorders and to compare clinical signs in diseases of the different pharyngeal areas. To review the investigation methods. METHODS: Medical ... [more ▼]

OBJECTIVES: To assess the frequency distribution of pharyngeal disorders and to compare clinical signs in diseases of the different pharyngeal areas. To review the investigation methods. METHODS: Medical records of 67 dogs presenting with abnormalities of the pharyngeal area were retrospectively reviewed and classified according to the anatomic area involved, i.e. the nasopharyngeal, oropharyngeal and laryngopharyngeal areas. Clinical signs, endoscopic findings and results of additional sampling were reviewed. RESULTS: Nasopharyngeal disorders were most frequently encountered (49 per cent), with choanal masses being the most frequent diagnosis (24 of 33), followed by laryngopharyngeal disorders (37.5 per cent) and oropharyngeal disorders (10.5 per cent). A rare condition, stenosis of the intrapharyngeal opening, was classified separately (3 per cent). An overall good correlation between matched cytology and histopathology samples was found. In all categories of diseases, clinical signs related to both the upper respiratory and digestive tracts were reported. CLINICAL SIGNIFICANCE: Pharyngeal disorders are more frequently localised in the nasopharyngeal area and include essentially choanal masses. The use of a flexible endoscope for retrograde rhinoscopy is essential for adequate investigation of the proximal nasopharyngeal area. Clinical signs do not allow differentiation of the pharyngeal disorder within the different pharyngeal areas. [less ▲]

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See detailInhaled fluticasone reduces bronchial responsiveness and airway inflammation in cats with mild chronic bronchitis
Kirschvink, N; Leemans, Jérôme ULg; Delvaux, François et al

in Journal of Feline Medicine and Surgery (2006), 8(1), 45-54

This study investigated the effect of inhaled fluticasone on lower airway inflammation and bronchial responsiveness (BR) to inhaled carbachol in cats with very mild, chronic bronchitis (n = 5) that were ... [more ▼]

This study investigated the effect of inhaled fluticasone on lower airway inflammation and bronchial responsiveness (BR) to inhaled carbachol in cats with very mild, chronic bronchitis (n = 5) that were compared with healthy cats serving as controls (n = 6). Chest radiographs, BR tests performed non-invasively by barometric whole body plethysmography (BWBP) and bronchoalveolar lavage (BAL) were performed before and after treatment. BR was quantified by calculating the concentration of carbachol inducing bronchoconstriction (C-Penh300%), defined as a 300% increase of baseline Penh, an index of bronchoconstriction obtained by BWBP. BAL fluid was analyzed cytologically and the oxidant marker 8-iso-PGF2α was determined. At test 1, healthy cats and cats with bronchitis were untreated, whereas for test 2 inhalant fluticasone (250 μg once daily) was administrated for 2 consecutive weeks to cats with bronchitis. Control cats remained untreated. Inhaled fluticasone induced a significant increase in C-Penh300% and a significant decrease of BAL fluid total cells, macrophages, neutrophils and 8-iso-PGF2α in cats with bronchitis, whilst untreated control cats did not show significant changes over time. This study shows that a 2-week fluticasone treatment significantly reduced lower airway inflammation in very mild bronchitis. BR could be successfully monitored in cats using BWPB and decreased significantly in response to inhaled fluticasone. 8-Iso-PGF2α in BAL fluid was responsive to treatment and appeared as a sensitive biomarker of lower airway inflammation in cats. [less ▲]

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See detailEffect of sampling method and culture conditions on the result of fungal culture in the diagnosis of canine sino-nasal aspergillosis.
Legarrérès, A.; Clercx, Cécile ULg; Mignon, Bernard ULg et al

in Proceedings of the 24th VCRS meeting (2006)

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See detailEvaluation of respiratory function by barometric whole-body plethysmography in healthy dogs
Talavera, J.; Kirschvink, N.; Schuller, S. et al

in Veterinary Journal (2006), 172(1), 67-77

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate ... [more ▼]

The objective of the present study was to assess the validity of barometric whole-body plethysmography (BWBP), to establish reference values, and to standardise a bronchoprovocative test to investigate airway responsiveness using BWBP in healthy dogs. BWBP measurements were obtained from six healthy beagle dogs using different protocols: (1) during three consecutive periods (3.5 min each) in two morning and two evening sessions; (2) before and after administration of two protocols of sedation; (3) before and after nebulisation of saline and increasing concentrations of carbachol and histamine both in conscious dogs and in dogs under both protocols of sedation. Enhanced pause (PENH) was used as index of bronchoconstriction. Basal BWBP measurements were also obtained in 22 healthy dogs of different breeds, age and weight. No significant influence of either time spent in the chamber or daytime was found for most respiratory variables but a significant dog effect was detected for most variables. A significant body weight effect was found on tidal volume and peak flow values (P < 0.05). Response to carbachol was not reproducible and always associated with side effects. Nebulisation of histamine induced a significant increase in respiratory rate, peak expiratory flow, peak expiratory flow/peak inspiratory flow ratio and PENH (P < 0.05). The response was reproduced in each dog at different concentrations of histamine. Sedation with acepromazine + buprenorphine had little influence on basal measurements and did not change the results of histamine challenge. It was concluded that BWBP is a safe, non invasive and reliable technique of investigation of lung function in dogs which provides new opportunities to characterise respiratory status, to evaluate airway hyperresponsiveness and to assess therapeutic interventions. (c) 2005 Elsevier Ltd. All rights reserved. [less ▲]

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See detailNon-invasive assessment of growth, gender and time of day related changes of respiratory pattern in healthy cats by use of barometric whole body plethysmography.
Kirschvink, Nathalie; Leemans, Jérôme ULg; Delvaux, François ULg et al

in Veterinary Journal (2006), 172(3), 446-454

The objective of this study was to establish a reference base for respiratory variables (respiratory rate [R(R)], inspiratory and expiratory time [T(i) and T(e)], peak inspiratory and expiratory ... [more ▼]

The objective of this study was to establish a reference base for respiratory variables (respiratory rate [R(R)], inspiratory and expiratory time [T(i) and T(e)], peak inspiratory and expiratory pseudoflow [PIF and PEF], tidal volume [V(T)], minute ventilation [V(E)] and enhanced pause [Penh]) of healthy cats by use of barometric whole body plethysmography (BWBP). Eighteen healthy European cats (10 male, 8 female) were studied from the age of 3 to 13 months in order to assess growth- and gender-related changes of BWBP variables. Chest radiographs and bronchoalveolar lavage cytology were performed to confirm pulmonary health status. Diurnal changes were investigated every 2 h over a period of 24 h when the cats were adult. V(T), V(E), PIF and PEF significantly increased during somatic growth and were higher in males than in females, whereas R(R), T(i), T(e), T(e)/T(i) ratio, PEF/PIF ratio and Penh remained unchanged and were not affected by gender. When measured over 24 h, Penh, T(e) and T(i) were significantly increased in the early morning hours (04:00 h), whereas R(R), PIF and PEF were decreased at that time. This study provides reference values of BWBP variables for healthy male and female cats and indicates when circadian changes might be observed [less ▲]

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See detailImmune-mediated respiratory and cardiac disease
Clercx, Cécile ULg; Day, M. J.

in Clinical Immunology of the Dog and Cat (2006)

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See detailImmune-mediated respiratory and cardiac disease
Clercx, Cécile ULg

in Day, M. J. (Ed.) Clinical Immunology of the Dog and Cat”, 1st edition (2006)

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See detailDiagnosis of canine sino-nasal aspergillosis: is quantification of Aspergillus DNA a useful technique?
Peeters, Dominique ULg; Peters, I. R.; Helps et al

in Proceedings of the 24th VCRS meeting (2006)

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See detailCytokine and chemokine expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinosinusitis.
Peeters, Dominique ULg; Peters, I. R.; Helps, C. et al

in Proceedings of the 16th Annual Congress of the ECVIM-CA (2006)

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