References of "Clercx, Cécile"
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See detailDetection of a new mutation responsible for primary ciliary dyskinesia in a pedigree of old English Sheepdogs
Merveille, Anne-Christine ULg; Bataille, G.; Davis, E. et al

in 19h ECVIM Meeting - Porto, Portugal - 8-10 septembre 2009 (2009, September)

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See detailRespiratory Disease : The coughing cat
Clercx, Cécile ULg

in Proceedings of the 61st SCIVAC National Congress (2009, March)

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See detailRespiratory Disease : Nasofrontal aspergillosis in dogs
Clercx, Cécile ULg

in Proceedings of the 61st SCIVAC National Congress (2009, March)

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See detailRespiratory Disease : Chronic nasal discharge in dogs and cats: only one symptom, several causes
Clercx, Cécile ULg; De Lorenzi, D.

in Proceedings of the 61st SCIVAC National Congress (2009, March)

See detailRespiratory Disease : Pulmonary function tests
Clercx, Cécile ULg

in Proceedings of the 61st SCIVAC National Congress (2009, March)

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See detailA pilot study comparing the antispasmodic effects of inhaled salmeterol, salbutamol and ipratropium bromide using different aerosoldevices on muscarinic bronchoconstriction in healthy cats
Leemans, Jérôme ULg; Kirschvink, Nathalie; Bernaerts, Frederique ULg et al

in Veterinary Journal (2009), 180

This study compared the duration and magnitude of the antispasmodic effects of salmeterol SLM), salbutamol (SAL), ipratropium bromide (IB) and the combination of SAL and IB (SAL/IB) against carbachol ... [more ▼]

This study compared the duration and magnitude of the antispasmodic effects of salmeterol SLM), salbutamol (SAL), ipratropium bromide (IB) and the combination of SAL and IB (SAL/IB) against carbachol-induced bronchoconstriction in healthy cats, and investigated the gain in efficacy using a two or fourfold increase in drug dosages. The drug regimens used were: (1) LM 25 lg, SAL 100 lg, IB 20 lg and SAL/IB 100 lg/20 lg for bronchodilators delivered by a metered-dose inhaler (MDI); (2) SAL 3.75 mg and IB 62.5 lg for nebulised (NEB) medications. To monitor the bronchodilator effect, airway responsiveness was assessed at different time points using barometric whole-body plethysmography and calculation of the concentration of inhaled carbachol inducing a 300% increase of baseline Penh (enhanced pause), an estimator of airflow limitation Maximum C-Penh300 was recorded 15 min after NEB SAL, IB MDI, NEB IB and 1 h after SAL MDI and 4 h after SLM MDI, respectively. C-Penh300 was significantly different from control values (without treatment) up to 24 h for SLM MDI, 8 h for IB MDI and 4 h for other drugs. In terms of efficacy, SAL/IB MDI showed a synergistic antispasmodic effect at 15 min, 4 h and 8 h after administration. A fourfold increase of the initial dose of IB MDI and NEB IB significantly increased C-Penh300. Despite a fourfold dose increase, SLM displayed the weakest degree of bronchoprotection compared to other bronchodilators. The study provides evidence that inhaled bronchodilators are efficient at preventing muscarinic-induced bronchospasm in healthy cats and that SAL and IB appear to be short-acting bronchodilators in contrast to SLM. [less ▲]

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See detailComparison of gene expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinitis: a microarray study
Vanherberghen, Morgane ULg; Bureau, Fabrice ULg; Peters, IR et al

in Proceedings of the 19th Annual ECVIM-CA Congress (2009)

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See detailEffect of sampling method and incubation temperature on fungal culture in canine sino-nasal aspergillosis
Billen, Frédéric ULg; Clercx, Cécile ULg; Le Garérrès, Alain et al

in Journal of Small Animal Practice (2009), 50(2), 67-72

OBJECTIVES: To evaluate the most appropriate sampling procedure and the effect of incubation temperature on fungal culture in the diagnosis of canine sinonasal aspergillosis (SNA). METHODS: Sixteen dogs ... [more ▼]

OBJECTIVES: To evaluate the most appropriate sampling procedure and the effect of incubation temperature on fungal culture in the diagnosis of canine sinonasal aspergillosis (SNA). METHODS: Sixteen dogs with SNA and 20 dogs with non-fungal nasal disease entered a prospective study. Nasal secretions and mucosal biopsies were collected in all dogs. Fungal plaques were also sampled in dogs with SNA. Each specimen was taken in duplicate from each dog and incubated at room temperature and 37 degrees C. RESULTS: In dogs with SNA, nasal secretions, mucosal biopsies and fungal plaques yielded fungal growth at room temperature in one, one and seven dogs, respectively, whereas fungal growth was obtained at 37 degrees C in three, 12 and 14 dogs, respectively. No specimen collected from any dog with non-fungal nasal disease yielded fungal growth at room temperature or at 37 degrees C. CLINICAL SIGNIFICANCE: The diagnosis of canine SNA is more likely to be confirmed following culture of mucosal biopsies or fungal plaques than nasal secretions sampled blindly with swabs. Incubating cultures at 37 degrees C is more likely to provide a diagnostic outcome than when samples are cultured at room temperature. Fungal culture of nasal specimens has good specificity for the diagnosis of SNA in dogs. [less ▲]

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See detailConcentration of allergen-specific IgE in serum and bronchoalveolar lavage fluid in dogs with eosinophilic bronchopneumopathy and dogs with chronic bronchitis.
Peyron, Clémence ULg; Derer, Michal; Day, M. J. et al

in Proceedings of the 19th Annual Congress of the ECVIM-CA (2009)

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See detailComparison of the value of measurement of serum galactomannan and Aspergillus-specific antibodies in the diagnosis of canine sino-nasal aspergillosis.
Billen, Frédéric ULg; Peeters, Dominique ULg; Peters, I. R. et al

in Veterinary Microbiology (2009), 133(4), 358-65

Serology is currently used for the diagnosis of canine sino-nasal aspergillosis (SNA). However, the accuracy of serological testing using commercially available, standardized purified antigen preparations ... [more ▼]

Serology is currently used for the diagnosis of canine sino-nasal aspergillosis (SNA). However, the accuracy of serological testing using commercially available, standardized purified antigen preparations of Aspergillus (CAPurAspAg) has only been poorly documented. The aim of the present study was to assess the diagnostic value of an agar-gel double immunodiffusion (AGDD) test and an anti-Aspergillus IgG ELISA, using CAPurAspAg and the commercially available Platelia test for the detection of serum galactomannan. Sera from 17 dogs with SNA, 18 dogs with a nasal tumour (NT), 11 dogs with lymphoplasmacytic rhinitis (LPR) and 33 control dogs were tested with the 3 methods. AGDD result was positive in 76.5% of dogs with SNA, whereas all sera from dogs with non-fungal nasal disease and control dogs were negative. A positive IgG ELISA result was obtained in 88% of dogs with SNA and in 18% of dogs with LPR. All patients with NT and control dogs had a negative IgG ELISA result. The Platelia test was positive in 24% of dogs with SNA, 11% of dogs with NT, 9% of dogs with LPR and 24% of control dogs. The results of this study suggest that (1) the detection of serum Aspergillus-specific antibodies with AGDD or ELISA, using CAPurAspAg, provides excellent specificity and good sensitivity, (2) the specificity is higher for AGDD (100%) than for ELISA (96.8%) while sensitivity is higher for ELISA (88.2%) than for AGDD (76.5%) and (3) serum galactomannan quantification with the Plateliat test is unreliable for the diagnosis of canine SNA. [less ▲]

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See detailAn Immunohistochemical Study of the Inflammatory Infiltrate Associated with Nasal Carcinoma in Dogs and Cats.
Vanherberghen, Morgane ULg; Day, M. J.; Gabriel, Alexandra et al

in Journal of Comparative Pathology (2009), 141(1)

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See detailCharacterisation of the acute and reversible airway inflammation induced by cadmium chloride inhalation in healthy dogs and evaluation of the effects of salbutamol and prednisolone.
Bolognin, M.; Kirschvink, N.; Leemans, Jérôme ULg et al

in Veterinary Journal (2009), 179(3), 443-450

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of ... [more ▼]

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of prednisolone or salbutamol treatment on the resulting bronchitis. The model characterisation and the effects of treatment were studied using clinical symptoms, haematology, thoracic radiography, bronchoscopy and bronchoalveolar lavage, barometric whole-body plethysmography and histamine broncho-provocation tests. In addition, the activity of matrix metalloproteinases (MMP)-2 and -9 were determined in serum and bronchoalveolar lavage fluid (BALF). Cadmium inhalation induced: (1) a transient bronchial inflammation, dominated by neutrophils; (2) a neutrophilia of the blood that persisted for up to 4weeks; (3) a transient increased bronchial reactivity, and (4) a significant increase in MMP-9 activity in the BALF. Prednisolone treatment reduced the influx of inflammatory cells into the BALF, but not significantly, had no effect on pulmonary function, and did not reduce of airway hypersensitivity. Salbutamol had almost no effect on any of the parameters investigated. [less ▲]

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See detailRespiratory diseases
Clercx, Cécile ULg

in Suter, P. F.; Kohn, B. (Eds.) Praktikum der Hundklinik, 10th Edition (2009)

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See detailCellular composition of bronchial brushings obtained from dogs with experimental chronic bronchitis
Bolognin, M.; Tual, Charlotte ULg; Day, M. J. et al

in 18th ECVIM Meeting - Gent - Belgique - 2-5 septembre 2008 (2008, September 02)

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See detailClinical and functional investigation in an experimental model of chronic bronchitis in dogs
Bolognin, M.; Bourguignon, V.; Hofman, A. C. et al

in 18th ECVIM Meeting - Gent - Belgique - 2-5 septembre 2008 (2008, September 02)

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See detailClinical efficacy of intrasinusal administration of bifonazole cream through perendoscopically placed catheters alone or in combination with enilconazole irrigation in canine sinonasal aspergillosis.
Billen, Frédéric ULg; Guieu, Liz-Valérie; Bernaerts, Frédérique et al

in Proceedings of the 18th ECVIM-CA Congress (2008, September)

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See detailComparison of three serological tests for the diagnosis of canine sino-nasal aspergillosis.
Billen, Frédéric ULg; Peeters, Dominique ULg; Peters, Iain et al

in Proceedings of the 18th ECVIM-CA Congress (2008, September)

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See detailPrimary ciliary dyskinesia and situs inversus in a young dog.
Cavrenne, Romain; De Busscher, Virginie; Bolen, Géraldine ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2008), 163(2), 54-5

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See detailClinical and functional responses to inhaled salmeterol in experimentally asthmatic cats with allergen-induced bronchospasm
Bernaerts, Frederique ULg; Leemans, Jérôme ULg; Kirschvink, N. et al

in Proceedings : 18th Congress European College of Veterinary Internal Medicine – companion animals (2008)

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