carence en vitamine D dans la population belge: Un vrai problème de santé publique?

Conference given outside the academic context (2007)

PTH stability : preanalytical conditios influences for Liaison (Diasorin)

in Clinical Chemistry & Laboratory Medicine (2007, June), 45

Analytical variation in plasma renin activity: Implications for the screening of primary aldosteronism

in Clinical Chemistry (2007), 53(4), 803-804

MDRD equation for GFR estimation : analytical limitations

Conference (2007, March 23)

Is cystatin C useful for the detection and the estimation of low glomerular filtration rate in heart transplant patients?

in Transplantation (2007), 83(5), 641-644

Although previously studied in patients with chronic kidney disease, there is less data for the use of cystatin C and cystatin C-based formulas in heart transplant recipients. The ability of creatinine ... [more ▼]

Although previously studied in patients with chronic kidney disease, there is less data for the use of cystatin C and cystatin C-based formulas in heart transplant recipients. The ability of creatinine and cystatin C to detect renal failure (glomerular filtration rate [GFR] below 60 mL/min/1.73 m(2)) in heart transplant patients has been compared. The accuracy and precision of a creatinine-based formula (Modification of Diet in Renal Disease [MDRD]) versus a cystatin C-based formula (Rule's formula) to estimate GFR have also been studied. GFR was measured using the (51)Crethylenediamine tetraacetic acid tracer in 27 patients. There was no significant difference between GFR and the reciprocal of creatinine or cystatin C. Receiver operating characteristic curves for cystatin C and creatinine were similar. Both formulas were well correlated with the GFR. The bias of the cystatin C-based was significantly better than one of the MDRD formula, but the standard deviation appeared better for the MDRD formula (bias of +3.9 mL/min/1.73 m(2) versus +12 mL/min/1.73 m(2) and SD of 8.5 versus 11.6, respectively). Plasma cystatin C has no clear advantage over serum creatinine to detect renal failure in heart transplanted patients. [less ▲]

Estimated glomerular filtration rate

in Annals of Internal Medicine (2007), 146(1), 74-74

Acetylcysteine and enzymatic creatinine: take care for interference!

in Acta Clinica Belgica (2007), 62(6), 462-462

The RIFLE criteria: are the foundations robust?

in Critical Care Medicine (2007), 35(11), 26692669-70

Analytical validation of the new version of the Liaison N-Tact PTH assay

in Clinical Chemistry & Laboratory Medicine (2007), 45(1), 105-107

We performed analytical validation of the new version of the Liaison N-Tact PTH (parathormone) assay according to NCCLS guidelines and compared this new generation of reagent with the Roche Elecsys PTH ... [more ▼]

We performed analytical validation of the new version of the Liaison N-Tact PTH (parathormone) assay according to NCCLS guidelines and compared this new generation of reagent with the Roche Elecsys PTH assay. We showed that this new version is a sensitive and precise method with good recovery. Significant carryover was observed, but with limited clinical implications. We demonstrated that the new version of the Liaison PTH is in reasonably good agreement with the Roche Elecsys PTH assay, and as we observed no differences in a hemodialyzed population, moving from one method to the other should not affect the daily follow-up of patients. However, one should be cautious with the highest values (> 500 pg/mL). We established reference intervals of 12-54 pg/mL for the Liaison and 14-52 pg/mL for the Elecsys assay. [less ▲]

High prevalence of vitamin D deficiency in pregnant women and new mothers in the area of Liège, Belgium

Poster (2007)