Sommes-nous tous déficitaires en vitamine D?

in Correspondances en MHDN (2011, June 09), 15(6), 191-195

Are we all vitamin-D deficient?

in Correspondances en MHDN (2011), 15(6), 191-195

Fatty acids and cardiovascular risk

in Clinical Chemistry & Laboratory Medicine (2011, May), 49(Special Suppl), 313

Vitamine D et aspects pratiques: quels dosages? pour qui? quelle supplémentation?

Conference (2011, May)

Fatty acids determinations: an cardiovascular risk? Preliminary results

in Biomedica - Life Science Summit (2011, April 07)

Are the creatinine-based equations accurate to estimate glomerular filtration rate in african american populations ?

in Clinical Journal of the American Society of Nephrology (2011), 6

Regarding the high prevalence of African American patients with ESRD, it is important to estimate the prevalence of early stages of chronic kidney disease in this specific population. Because serum ... [more ▼]

Regarding the high prevalence of African American patients with ESRD, it is important to estimate the prevalence of early stages of chronic kidney disease in this specific population. Because serum creatinine concentration is dependent on muscular mass, an ethnic factor has to be applied to creatinine-based equations. Such ethnic factors have been proposed in the Modification of Diet in Renal Disease (MDRD) study equation and in the more recent Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. This review analyzes how these correction factors have been developed and how they have, or have not, been validated in external populations. It will be demonstrated that the African American factor in the MDRD study equation is accurate in African American chronic kidney disease (CKD) patients. However, it will be shown that this factor is probably too high for subjects with a GFR of >60 ml/min per 1.73 m2, leading to an underestimation of the prevalence of CKD in the global African American population. It will also be confirmed that this ethnic factor is not accurate in African (non-American) subjects. Lastly, the lack of true external validation of the new CKD-EPI equations will be discussed. Additional trials seem necessary in American African and African populations to better estimate GFR and apprehend the true prevalence of CKD in this population with a high renal risk. [less ▲]

Paricalcitol for reduction of albuminuria in diabetes

in Journal-Lancet (The) (2011), 377

Overestimation of the 25OHD serum concentration with the automated IDS EIA kit.

in Journal of Bone and Mineral Research (2011), 26(2), 434-6

We have recently observed an increasing number of patients presenting very high serum levels of 25-hydroxyvitamin D [25(OH)D] (> 150 ng/mL), which, in all cases, had been measured with the IDS EIA kit ... [more ▼]

We have recently observed an increasing number of patients presenting very high serum levels of 25-hydroxyvitamin D [25(OH)D] (> 150 ng/mL), which, in all cases, had been measured with the IDS EIA kit adapted on different "open" automated platforms. We performed a comparison between the IDS EIA kit adapted on two different "open"automated platforms and the DiaSorin RIA. We found a systematic bias (higher levels with the IDS EIA kit) for concentrations more than 50-60 ng/mL that was less obvious when the IDS EIA was used in its manual procedure. We thus suggest to use the IDS EIA kit in its manual procedure rather than to adapt it on an automated platform, and to interpret cautiously a 25(OH)D greater than 100 ng/mL with this kit. [less ▲]

Vitamine D et grossesse

Learning material (2011)

Recommandations pour le choix et l'harmonisation des techniques de dosage de la créatinine

in Annales de Biologie Clinique (2011), 69(1), 9-16

En 2010, un groupe de travail mixte constitué de la Société française de biologie clinique (SFBC) et de la Société de nephrologie (SN) a formulé les propositions suivantes afin de réactualiser les ... [more ▼]

En 2010, un groupe de travail mixte constitué de la Société française de biologie clinique (SFBC) et de la Société de nephrologie (SN) a formulé les propositions suivantes afin de réactualiser les recommanadations pour le dosage de la créatinine plasmatique. [less ▲]