Showing results 41 to 60 of 242
  Dosage des opiacés, cocaïne et amphéramines dans le sérum par UPLC/MSMSDubois, Nathalie  ; Debrus, Benjamin ; Charlier, Corinne in Acta Clinica Belgica (2010), 65(1), 75-84 Detailed reference viewed: 93 (16 ULg)Quantitative Determination of eight organochlorine pesticides in serum by GC coupled to tandem mass spectrometryDubois, Nathalie ; ; Charlier, Corinne in Acta Clinica Belgica (2010), 65(1), 58-64 Detailed reference viewed: 27 (13 ULg)Validated quantitative simultaneous determination of cocaine opiates and amphetamines in serum by U-HPLC coupled to tandem mass spectrometryDubois, Nathalie ; Debrus, Benjamin ; Hubert, Philippe et alin Acta Clinica Belgica (2010), 65(Supplement 1), Detailed reference viewed: 78 (23 ULg) Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant materialDe Backer, Benjamin ; Debrus, Benjamin ; Lebrun, Pierre et alin Journal of Chromatography. B : Analytical Technologies in the Biomedical & Life Sciences (2009), 877(32), 4115-4124 GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their ... [more ▼] GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their neutral counterparts. Conversely, HPLC permits the determination of the original composition of plant cannabinoids by direct analysis. Several HPLC methods have been described in the literature, but most of them failed to separate efficiently all the cannabinoids or were not validated according to general guidelines. By use of an innovative methodology for modelling chromatographic responses, a simple and accurate HPLC/DAD method was developed for the quantification of major neutral and acidic cannabinoids present in cannabis plant material: Δ9-tetrahydrocannabinol (THC), THC-acid (THCA), cannabidiol (CBD), CBD-acid (CBDA), cannabigerol (CBG), CBG-acid (CBGA) and cannabinol (CBN). Δ8-tetrahydrocannabinol (∆8-THC) was determined qualitatively. Following the practice of design of experiments, predictive multilinear models were developed and used in order to find optimal chromatographic analytical conditions. The method was validated following an approach using accuracy profiles based on β-expectation tolerance intervals for the total error measurement, and assessing the measurements uncertainty. This analytical method can be used for diverse applications, e.g. plant phenotype determination, evaluation of psychoactive potency and control of material quality. [less ▲] Detailed reference viewed: 249 (83 ULg)Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant materialDe Backer, Benjamin ; Debrus, Benjamin ; Lebrun, Pierre et alPoster (2009, October) Detailed reference viewed: 29 (14 ULg)Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant materialDe Backer, Benjamin ; Debrus, Benjamin ; Lebrun, Pierre et alConference (2009, October) Detailed reference viewed: 28 (14 ULg)Etude comparative des résultats de dosage des métaux dans le sang obtenus sur différents types de prélèvementsLognard, Michaël ; Dubois, Nathalie ; et alPoster (2009, October) Detailed reference viewed: 18 (5 ULg)Fatal intoxications by acenocoumarol, phenprocoumon and warfarin: method validation in blood using the total error approach.Denooz, Raphael ; ; Charlier, Corinne in Journal of Chromatography. B : Analytical Technologies in the Biomedical & Life Sciences (2009), 877(23), 2344-2348 Detailed reference viewed: 41 (17 ULg)Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoïds in cannabis plant materialDe Backer, Benjamin ; Debrus, Benjamin ; Lebrun, Pierre et alPoster (2009, August) GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their ... [more ▼] GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their neutral counterparts. Converely, HPLC permits the determination of the original composition of plant cannabinoids by direct analysis. Several HPLC methods have been described in the literature, but most of them failed to separate efficiently all the cannabinoids or were not validated according to general guidelines. By use of an innovative methodology for modelling chromatographic responses, a simple and accurate HPLC/DAD method was develop [less ▲] Detailed reference viewed: 124 (63 ULg)Le cosméceutique, oxymoron de la quête d'une efficacité cosmétique?Pierard, Gérald ; ; Franchimont, Claudine et alin Dermatologie Actualité (2009), 113 Detailed reference viewed: 83 (13 ULg)Comment j'explore... des lésions cutanées chez un toxicomane adepte de la cocaïne ou du crack.Devillers, Céline ; Franchimont, Claudine ; Pierard, Gérald et alin Revue Médicale de Liège (2009), 64 Both cocaine and crack exert sympathetic and prothrombotic effects. The induced lesion may affect the skin, and other organ systems as well. Various types of vasculitis and infectious dermatoses are the ... [more ▼] Both cocaine and crack exert sympathetic and prothrombotic effects. The induced lesion may affect the skin, and other organ systems as well. Various types of vasculitis and infectious dermatoses are the predominant issues. In addition, tactile and visual hallucinations may occur suggesting insect crawling underneath the skin. [less ▲] Detailed reference viewed: 66 (8 ULg)Evaluation biologique du stress oxydant : application en routine clinique.Pincemail, Joël ; Le Goff, Caroline ; Charlier, Corinne et alin Nutritions & Endocrinologie (2009), Déc Detailed reference viewed: 64 (14 ULg)Pathologies endocriniennes observées chez l'Homme en rapport avec l'exposition aux pesticides organochlorésCharlier, Corinne in Annales de Toxicologie Analytique (2009), 21(3), 113-117 Detailed reference viewed: 19 (10 ULg)Fondements de la cosmétovigilance sur le mode européen.Franchimont, Claudine ; ; Quatresooz, Pascale et alin Skin (2009), 12 Detailed reference viewed: 50 (16 ULg)Cocaïne and metabolites in waste and surface water across Belgium.; ; Theunis, Laetitia et alin Environmental Pollution (2009), 157 Detailed reference viewed: 83 (45 ULg)Perturbations endocriniennes liées aux polluants environnementauxCharlier, Corinne Conference (2009) Detailed reference viewed: 26 (8 ULg)Coke dans nos rivières: une application originale de toxicologie environnementaleCharlier, Corinne Conference (2009) Detailed reference viewed: 10 (8 ULg)Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium; ; Theunis, Laetitia et alin Addiction (2009), 104 Detailed reference viewed: 61 (26 ULg)Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste- and surface water from Belgium and removal during wastewater treatment; ; Theunis, Laetitia et alin Water Research (2009), 43 Detailed reference viewed: 27 (12 ULg)Les perturbateurs endocriniens et le monde agricoleCharlier, Corinne Conference (2009) Detailed reference viewed: 12 (4 ULg) |
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