References of "Bruyère, Olivier"
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See detailValidity and Reliability of the French version of the STarT Back Screening Tool for patients with low back pain.
Bruyère, Olivier ULg; Demoulin, Maryline; Beaudart, Charlotte ULg et al

in Spine (2014), 39(2), 123-128

Study Design. Observational prospective study.Objective. Our objective was to assess the reliability and validity of the French version of the Keele STarT Back Screening Tool (SBST).Summary of Background ... [more ▼]

Study Design. Observational prospective study.Objective. Our objective was to assess the reliability and validity of the French version of the Keele STarT Back Screening Tool (SBST).Summary of Background Data. The SBST is a recently validated tool developed to identify subgroups of patients with low back pain (LBP) to guide early secondary prevention in primary care.Methods. Outpatients with LBP aged 18 years or more, attending a rehabilitation centre, a back school, a private physiotherapy unit or a fitness centre were included. Patients were assessed through the SBST, Roland-Morris Disability Questionnaire (RMDQ), Orebro Musculoskeletal Pain Screening Questionnaire (OMPSQ), Medical Outcomes Survey Short Form 36 (SF-36) questionnaire, and a pain visual analogic scale (VAS). Test-retest reliability was assessed with Kappa score or the intraclass correlation coefficient (ICC), internal consistency of the psychological subscale with the Cronbach alpha coefficient, construct validity with the Spearman's correlation coefficient, and floor and ceiling effects by percentage frequency of lowest or highest possible score achieved by respondents.Results. 108 patients with LBP were included. The test-retest reliability of the SBST total score was excellent with an ICC of 0.90 (0.81-0.95). The Cronbach alpha coefficient was 0.73 showing a good internal consistency for the psychological subscale. High Spearman's correlation coefficients of 0.74 between SBST and RMDQ, and 0.74 between the SBST and OMPSQ were observed. As expected, low to moderate correlations were observed between the SBST total score and some dissimilar measures of the SF-36. The lowest possible SBST score was observed for 8 patients (7.4%) whereas only three patients (2.8%) had the highest possible SBST score.Conclusion. The French version of the SBST is a reliable and valid questionnaire consistent with the original English version. Therefore, this new version may help French-speaking clinicians and scientists to stratify patients with LBP. [less ▲]

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See detailEvolution over two years of functional and motor abilities among nursing home residents
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 45

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See detailPrevalence of sarcopenia according to different diagnostic tools
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Slomian, Justine ULg et al

in Journal of Frailty & Aging (2014), 3(1), 43

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See detailRepublished: Value of biomarkers in osteoarthritis: current status and perspectives.
Lotz, M.; Martel-Pelletier, J.; Christiansen, C. et al

in Postgraduate Medical Journal (2014), 90(1061), 171-8

Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation. Biomarkers are being developed to quantify joint ... [more ▼]

Osteoarthritis affects the whole joint structure with progressive changes in cartilage, menisci, ligaments and subchondral bone, and synovial inflammation. Biomarkers are being developed to quantify joint remodelling and disease progression. This article was prepared following a working meeting of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis convened to discuss the value of biochemical markers of matrix metabolism in drug development in osteoarthritis. The best candidates are generally molecules or molecular fragments present in cartilage, bone or synovium and may be specific to one type of joint tissue or common to them all. Many currently investigated biomarkers are associated with collagen metabolism in cartilage or bone, or aggrecan metabolism in cartilage. Other biomarkers are related to non-collagenous proteins, inflammation and/or fibrosis. Biomarkers in osteoarthritis can be categorised using the burden of disease, investigative, prognostic, efficacy of intervention, diagnostic and safety classification. There are a number of promising candidates, notably urinary C-terminal telopeptide of collagen type II and serum cartilage oligomeric protein, although none is sufficiently discriminating to differentiate between individual patients and controls (diagnostic) or between patients with different disease severities (burden of disease), predict prognosis in individuals with or without osteoarthritis (prognostic) or perform so consistently that it could function as a surrogate outcome in clinical trials (efficacy of intervention). Future avenues for research include exploration of underlying mechanisms of disease and development of new biomarkers; technological development; the 'omics' (genomics, metabolomics, proteomics and lipidomics); design of aggregate scores combining a panel of biomarkers and/or imaging markers into single diagnostic algorithms; and investigation into the relationship between biomarkers and prognosis. [less ▲]

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See detailLe tradipraticien est un acteur crédible dans l'offre des soins en territoire périurbain: Résultats d'une étude menée dans la commune de Kisenso à Kinshasa, Congo
Manzambi Kuwekita, Joseph ULg; Mbadu Kivuidi, Véronique; Bruyère, Olivier ULg et al

Conference (2013, December 19)

Cette étude examine la perception des tradipraticiens par les populations, afin d’envisager leur intégration dans les politiques de développement de Kisenso par des focus groupes en juillet 2013. 100% de ... [more ▼]

Cette étude examine la perception des tradipraticiens par les populations, afin d’envisager leur intégration dans les politiques de développement de Kisenso par des focus groupes en juillet 2013. 100% de participants reconnaissent l’existence de tradipraticiens et les avoir déjà consultés, 80% déclarent avoir expérimenté la guérison totale. Le recours au tradipraticien est justifié par l’efficacité des soins, le type de maladie, la compétence, la proximité et la possibilité de paiement à crédit. Pour 70% des participants, le tradipraticien doit améliorer les conditions d’hygiène dans la manipulation des produits. La quasi-totalité des tradipraticiens ne sont pas autorisés à fonctionner, dû notamment au coût d’actes administratifs pour l’obtention de l’autorisation et la peur de s’ouvrir aux intellectuels. 20% d’entre eux disent collaborer avec la biomédecine pour les soins de "mbasu", 20% se déclarent spécialistes en ostéologie, 20% dans les soins de "mbasu" et 60% disent tout soigner. Si l’on veut intégrer les tradipraticiens dans les politiques de développement local, on devra supprimer le coût d’actes administratifs, leur accorder des formations, intégrer les soins traditionnels dans les paquets d’activités et leur accorder le statut d’agent de l’Etat. [less ▲]

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See detailLes acteurs non étatiques jouent un rôle déterminant dans le fonctionnement des services publics en territoires périurbains
Manzambi Kuwekita, Joseph ULg; Bruyère, Olivier ULg; REGINSTER, Jean-Yves ULg et al

Poster (2013, December 19)

Cette étude répertorie les acteurs étatiques et non étatiques qui offrent des services publics aux populations en territoire périurbain en vue d’améliorer leur intégration dans les politiques de ... [more ▼]

Cette étude répertorie les acteurs étatiques et non étatiques qui offrent des services publics aux populations en territoire périurbain en vue d’améliorer leur intégration dans les politiques de développement local de la commune périurbaine de Kisenso à Kinshasa, par des focus groups en juillet 2013. La question de recherche était : « quels sont les acteurs étatiques et non étatiques qui offrent les services publics en territoire périurbain, leurs rapports avec l’administration publique et comment envisager leur intégration dans les politiques de développement local » ? Les principaux résultats de cette étude montrent qu’à Kisenso, 5 acteurs étatiques et 75 acteurs non étatiques opèrent dans la commune de Kisenso, essentiellement dans les domaines suivants : santé, éducation, justice, social, environnement, énergie, PME, etc. en ce qui concerne les rapports qu’entretiennent les acteurs non étatiques avec l’Etat, (i) tous sont reconnus par la Commune car ils détiennent des autorisations délivrées par les instances de niveau national, (ii) ils ne rendent pas compte à la commune de leurs activités de manière formelle parce la loi ne les y oblige pas. 109 structures de santé sont fonctionnelles. Néanmoins, environ une trentaine d’ONGs transmettent leurs rapports d’activités à la Commune en fin d’année. De même, les acteurs non étatiques évoluant dans le secteur des soins de santé transmettent tous leurs rapports épidémiologiques, mais seulement 15/109 (soit 13,7%) rapportent sur les activités (SNIS). À la question de savoir pourquoi la population recourt aux services offerts par les différents acteurs, cette étude montre que les choix des populations pour un service ou un autre sont motivés essentiellement par la qualité de ces services, la compétence du personnel, l’efficacité, l’accueil, les coûts accessibles, l’accueil et la proximité du service avec le ménage. Quant à la manière d’intégrer les acteurs non étatiques dans les politiques de développement local, les acteurs ont proposé le processus suivant : (i) inventorier les structures et/ou les acteurs œuvrant dans la zone de santé et/ou la commune, (ii) faire les états des lieux pour identifier leur degré de fonctionnement, (iii) accorder les autorisations aux structures qui remplissent les conditions de fonctionnement, (iv) aider celles qui ne remplissent pas ces conditions à les remplir par la formation du personnel, la subvention des structures, etc.). Les résultats de cette recherche suggèrent que si l’on veut éviter que certains acteurs continuent à opérer dans la clandestinité pour des raisons d’ordre financier, à l’instar de tradipraticiens, ils devraient être exonérés de toutes taxes. Les résultats de cette recherche montrent que si l’on veut intégrer les acteurs non étatiques dans les politiques de développement local, les différentes autorités municipales devraient les associer, en amont, aux activités organisées telles la formation et la supervision, sans que cela ne leur soit facturé ; leur demander ensuite de rapporter sur leurs activités ne devrait plus entraîner de résistance. [less ▲]

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See detailÉtude des conditions de vie et d’accessibilité aux soins de santé de qualité des populations en situation de précarité, dans la zone de sante de Bandalungwa à Kinshasa (Congo) grâce à la micro-assurance santé en 2008.
Manzambi Kuwekita, Joseph ULg; Guillaume, Michèle ULg; Balula Semutsari, Marie-Paule et al

in Journal d’Épidémiologie et de Santé Publique (2013), 12

This study investigates the conditions under which populations living in poverty are able to accumulate savings and contribute to a micro-insurance health system to improve their living standards and ... [more ▼]

This study investigates the conditions under which populations living in poverty are able to accumulate savings and contribute to a micro-insurance health system to improve their living standards and access quality health care. We carried out a comprehensive survey in 2008 in the Bandalungwa health zone of Kinshasa. It was based on the Manzambi Model for health financing and the extension of social protection to the poor in developing countries. Each day, the leader of the group hands the members’ contributions to a loan officer. Two micro -entrepreneurs (3%) paid by these funds have disappeared, with the help of a loan officer. The main results of this study show that of all those contributing to the scheme, 78.1% improved their living conditions. 50% were able to start saving while 71.9% of these regularly contributed 1 US$ to the micro-insurance fund. 40.6% regularly contributed 1 US$ to the health micro-insurance fund, 88.5% of these improved their access to health care. When micro-credit promotes significant compulsory savings, the obligatory contribution of one dollar a day to the micro-insurance fund becomes easier and results in improved access to care (p<0.000) for household members. 68% of micro-entrepreneurs who paid their dues improved their purchasing power. If we want to keep people out of poverty, we must find a way to help them with these compulsory savings. The results of this study show that micro-entrepreneurs who have improved their living conditions also saw an improvement in their access to care (86.4%) (p=0.003). The Manzambi model provides a sustainable solution to the problem of health financing and extends social protection to fragile populations in developing countries. It also brings us closer to the objective of "health for all". [less ▲]

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See detailIl n'est jamais trop tard pour apprendre à (bien) lire ...
Bruyère, Olivier ULg

in Medi-Sphere (2013), 421

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See detailUne infiltration de plasma riche en plaquettes (PRP) pour traiter les tendinopathies rotuliennes supérieures chroniques
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in Annals of Physical and Rehabilitation Medicine (2013, October), 56(Sup 1),

Objective: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

Objective: Jumper’s knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. Infiltration of platelet-rich plasma (PRP) could be a new therapy for such chronic tendinopathies. Materiel and methods: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10-point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA-P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub-maximal eccentric reeducation. Results: Pain during daily activities significantly decreased with time (especially after 6 weeks and continued to a lesser extend up to 3 months). During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. Discussion: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol is efficient to improve symptoms of chronic jumper’s knee in patients non-responsive to classical conservative treatments. [less ▲]

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See detailMicro-crédit, Augmentation du pouvoir d’achat et Amélioration des conditions de vie des populations précaires en milieu urbain africain : Résultats d’une expérience menée dans la zone de santé de Bandalungwa à Kinshasa, Congo.
Manzambi Kuwekita, Joseph ULg; Gosset, Christiane ULg; Guillaume, Michèle ULg et al

in Psychologie et Société Nouvelle (2013), XII(3), 3-14

Purchasing power increase, improvement of living conditions and health funding of vulnerable people in African urban areas: the case of the health zone of Bandalungwa, Kinshasa (Congo) Through a survey ... [more ▼]

Purchasing power increase, improvement of living conditions and health funding of vulnerable people in African urban areas: the case of the health zone of Bandalungwa, Kinshasa (Congo) Through a survey, the study analyses the living improvement possibilities for microentrepreneurs, by the improvement of their purchasing power through microcredits provided by the Programme National d’Appui à la Protection Sociale (PNPS), in the health zone of Bandalungwa (Kinshasa). The credits were affected to wheat flour, starches, fresh food, fruits and vegetables, small restoration, smoked fish, clothing, electronic devices. Main results suggest that 68% of the microentrepreneurs financed by the program have declared improved living conditions. This improvement was associated to access to health care, children schooling, household’s access to food, loan reimbursement, and rent payment. The bivariate analysis has shown that those who had invested the whole credit in the funded activity experienced living improvement. To help vulnerable people in increasing their purchasing power, the loans should be linked to projects that are helpful to the households, and avoid that households use the credit in unsuitable ways, which could maintain them in a high level of debt. [less ▲]

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See detailCritères de retour sur le terrain après plastie LCA chez le footballeur professionnel
Croisier, Jean-Louis ULg; Rochcongar, Pierre; Bruyère, Olivier ULg et al

in European Journal of Sports Medicine (2013, September), 1(1),

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See detailCaractéristiques cliniques des sujets répondeurs à la vibrotonie corporelle totale
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Maquet, Didier ULg et al

in Cahiers de l'Année Gérontologique (Les) (2013, September), 5(1-2), 118-119

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See detailImportance du déficit en vitamine D chez les femmes françaises ostéoporotiques et ostéopéniques âgées de plus de 80 ans
Bruyère, Olivier ULg; Slomian, Justine ULg; Beaudart, Charlotte ULg et al

in Cahiers de l'Année Gérontologique (Les) (2013, September), 5(1-2), 75

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See detailLes effets d'une supplémentation en vitamine D sur la force musculaire : une méta-analyse d'essais randomisés contrôlés
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Rabenda, Véronique ULg et al

in Cahiers de l'Année Gérontologique (Les) (2013, September), 5(1-2), 38

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See detailRisk of hip fracture in community-dwelling and institutionalized osteoporotic patients: A 3-year study.
Bruyère, Olivier ULg; Hiligsmann, Mickaël ULg; Zegels, Brigitte ULg et al

in International Journal of Gerontology (2013), 7(3), 167-70

Background and aims: It has been previously suggested that the incidence of hip fracture is higher among people living in nursing homes than among community-dwelling people. However, it is not clear ... [more ▼]

Background and aims: It has been previously suggested that the incidence of hip fracture is higher among people living in nursing homes than among community-dwelling people. However, it is not clear whether this is a consequence of nursing home residency or of the greater age of the residents. We have examined the relationship between the place of residence and hip fracture incidence, in a prospective 3- year study. Methods: Women from nine countries included in this study were part of the placebo group of a randomized controlled trial having assessed the long-term effect of a new antiosteoporotic drug. All women were osteoporotic and received placebo and vitamin D during the 3 years of follow-up. All the institutionalized (nursing home, medical house) women (n ¼ 217) were included in this post hoc analysis and three noninstitutionalized age- and country-matched controls were included (n ¼ 651). Results: The mean (and standard deviation) age of the patients was 80.4 (5.6) years in the institutionalized women and 80.2 (5.8) years in the noninstitutionalized women (p ¼ 0.87). After 3 years of followup, 37 fractures occurred: 12 (5.5%) in institutionalized women and 25 (3.8%) in noninstitutionalized women. The difference between the two groups was not statistically significant (p ¼ 0.29). After controlling for age, body mass index, femoral neck bone mineral density and prevalent nonvertebral fracture, the residence status of the patient (institutionalized vs. noninstitutionalized) was not significantly associated with hip fracture incidence (p ¼ 0.63). Conclusions: We suggest that living in an institutionalized place is not an independent risk factor for hip fracture for osteoporotic women receiving calcium and vitamin D. [less ▲]

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See detailQuality of life in sarcopenia and frailty
Rizzoli, René; Reginster, Jean-Yves ULg; Arnal, Jean-François et al

in Calcified Tissue International (2013), 93

The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may ... [more ▼]

The reduced muscle mass and impaired muscle performance that define sarcopenia in older individuals are associated with increased risk of physical limitation and a variety of chronic diseases. They may also contribute to clinical frailty. A gradual erosion of quality of life (QoL) has been evidenced in these individuals, although much of this research has been done using generic QoL instruments, particularly the SF-36, which may not be ideal in older populations with significant comorbidities. This review and report of an expert meeting presents the current definitions of these geriatric syndromes (sarcopenia and frailty). It then briefly summarizes QoL concepts and specificities in older populations and examines the relevant domains of QoL and what is known concerning QoL decline with these conditions. It calls for a clearer definition of the construct of disability, argues that a disease-specific QoL instrumentfor sarcopenia/frailty would be an asset for future research, and discusses whether there are available and validated components that could be used to this end and whether the psychometric properties of these instruments are sufficiently tested. It calls also for an approach using utility weighting to provide some cost estimates and suggests that a time trade-off study could be appropriate. [less ▲]

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See detailPlatelet-rich plasma (PRP) to treat chronic upper patellar tendinopathies
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in British Journal of Sports Medicine (2013, July), 47(10 (e3)), 15

Background: Upper patellar tendinopathies remain often chronic and rebel to a thorough conservative treatment. Moreover, the option of a surgical treatment could be disappointing. New treatments are being ... [more ▼]

Background: Upper patellar tendinopathies remain often chronic and rebel to a thorough conservative treatment. Moreover, the option of a surgical treatment could be disappointing. New treatments are being developed. Injection of PRP is one of these. Platelets contain lot of growth factors which would have the potentiality to enhance the healing process of tendons. Even if in vitro and animal experiments have demonstrated this stimulation of tendon healing process1, clinical series are subject to controversy2. Methods: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments [VAS, clinical examination with an algometer, algofunctional scores (IKDC and VISA-P), functional assessments (isokinetic and Optojump) and imagery (ultrasounds and MRI)]were made before infiltration of PRP, and 6 weeks and 3 months after. The PRP was obtained by an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a 6-week standardised sub-maximal eccentric reeducation. Results: We observed a very significant improvement of the algofunctional status as soon as 6 weeks after the infiltration of PRP, and continued to a lesser extent up to 3 months. During functional evaluation, pain decreased as well, but without significant improvement of performances. No significant improvements in the imagery were observed. Interestingly, patients who had a VAS equal or below 1 after 3 months post-infiltration were younger (24.7 vs 32.2 y.o.). Moreover, these younger patients had a significant increase of the IKDC score (p=0.003), a significant improvement of pain during isokinetic evaluations (p<0.05), and during Optojump assessments (p=0.01). Seventy-five percent of subjects were able to return to sport, even if only half of these patients recovered the same level than before the tendinopathy. Discussion / Conclusions: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol is efficient to improve symptoms of chronic upper patellar tendinopathies, non-responsive to classical conservative treatments. However, up to now, there is no consensus on the method to prepare the PRP. Indeed, each technique could provide a very different PRP (variations in the platelet concentrations and of the amount of red and white cells). [less ▲]

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