References of "Bonnet, Pierre"
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See detailThe effects of shunting sytemic venous blood into the portal circulation. Review, experiences and future perspectives
D'Silva, Milbhor; Wolf, P.; Bonnet, Pierre ULg

in Archives of Hellenic Medecine (1997), 14(3), 246-264

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See detailCombined Liver - Spleen -small intestine grafting in a rat model: Role of transplanting additional lymphoid tissue on survival.
D'Silva, Milbhor; Pirenne, Jacques; Nakhleh, R. E. et al

in International Surgery (1996), (81), 109-114

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See detailL'acte sexuel féminin: Son intégration dans la conception anatomo-physiologique du plancher pelvien.
Mouchel, Jean; Beco, Jacques ULg; Bonnet, Pierre ULg et al

in Tournaire, M.; Philippe, H. J. (Eds.) Mise à jour en Gynécologie-Obstétrique 1996 (1996)

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See detailRat heart-aorta cluster transplantation : a novel model to study transplant rejection
D'Silva, Milbhor; Candidas, D.; Lee, S. et al

in Transplant International (1995), (8), 298-306

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See detailLaparoscopic adrenalectomy in pheochromocytoma and Cushing's syndrome. Reflections about two case reports.
Meurisse, Michel ULg; Joris, Jean ULg; Hamoir, Etienne ULg et al

in Acta Chirurgica Belgica (1994), 94(6), 301-6

Laparoscopic adrenalectomy is possible as well on the left as on the right side using a percutaneous transabdominal approach. The exposure of the glands seems better than it could be achieved with an open ... [more ▼]

Laparoscopic adrenalectomy is possible as well on the left as on the right side using a percutaneous transabdominal approach. The exposure of the glands seems better than it could be achieved with an open method. In combination with intraoperative infusion of nicardipine, a calcium-channel blocker, the laparoscopic removal of a pheochromocytoma was performed safely and under stable conditions. In case of Cushing's syndrome, the laparoscopic approach reduces the problems related to poor healing. In all cases of laparoscopic adrenalectomy, this approach could offer the clear advantages of smaller incisions, reduced postoperative pain and incisional discomfort as well as complications related to large and invasive procedure and finally allows quicker recovery. Moreover, conversion to open surgery remains always possible, if needed. [less ▲]

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See detailThe experience of the CHU Liege with conservative surgery in the management of upper urinary tract tumors.
Bouffioux, Christian ULg; Andrianne, Robert ULg; Bonnet, Pierre ULg et al

in Acta Urologica Belgica (1994), 62(4), 39-43

A review of 20 cases of conservative surgery for urothelial tumors of the upper tract is presented. The morbidity is limited; the recurrence rate is around 15% in the ipsilateral urinary tract with a mean ... [more ▼]

A review of 20 cases of conservative surgery for urothelial tumors of the upper tract is presented. The morbidity is limited; the recurrence rate is around 15% in the ipsilateral urinary tract with a mean follow up of 41 months. Conservative surgery does not seem to carry a higher fatal risk as compared to more radical surgery. It has indications in some cases which are defined. [less ▲]

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See detailTechnique for Ventricular Wrapping in Experimental Dynamic Cardiomyoplasty
Radermecker, Marc ULg; Bonnet, Pierre ULg; Philippart, C. et al

in Acta Chirurgica Belgica (1994), 94(5, Sep-Oct), 266-71

Cardiomyoplasty is a wrapping of an electrostimulated latissimus dorsi muscle flap around the heart for substitution and/or reinforcement. The surgical technique for reproducible cardiomyoplasties in the ... [more ▼]

Cardiomyoplasty is a wrapping of an electrostimulated latissimus dorsi muscle flap around the heart for substitution and/or reinforcement. The surgical technique for reproducible cardiomyoplasties in the goat model is presented. The methods combine the direction of wrapping (clockwise, counter-clockwise) and the orientation of muscle fibers. A cardiomyoplasty model using right and left latissimus dorsi or left latissimus dorsi and pectoralis major as well as a split muscle technique are illustrated. [less ▲]

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See detailThe experience of radical prostatectomy for locally confined prostate cancer in Liege.
Bouffioux, Christian ULg; de Leval, Jean ULg; Andrianne, Robert ULg et al

in Acta Urologica Belgica (1994), 62(1), 51-9

The authors report their experience of 148 radical prostatectomies performed for adeno-carcinoma. They expose the reasons which have led them to adopt this kind of treatment and the reasons explaining a ... [more ▼]

The authors report their experience of 148 radical prostatectomies performed for adeno-carcinoma. They expose the reasons which have led them to adopt this kind of treatment and the reasons explaining a nearly exponential increase of the frequency of the operation during the last 5 years. They underline the importance of lymphadenectomy and the safety of frozen sections of the nodes. The surgical technique is briefly commented and the (low) morbidity of the operation is reviewed. They compare the results of RPV to those of external radiotherapy, watchful attitude or immediate hormonal treatment and they conclude in insisting on the benefit of the surgical approach as far as indications (which are defined) are strictly followed. [less ▲]

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See detailBenign Prostatic Hyperplasia and Normal Prostate Aging: Differences in Types I and Ii 5 Alpha-Reductase and Steroid Hormone Receptor Messenger Ribonucleic Acid (Mrna) Levels, but Not in Insulin-Like Growth Factor Mrna Levels
Bonnet, Pierre ULg; Reiter, E.; Bruyninx, M. et al

in Journal of Clinical Endocrinology and Metabolism (The) (1993), 77(5), 1203-8

Benign prostatic hyperplasia (BPH) is so common in elderly men that the development of adenomatous nodules in this organ can be seen as a normal age-dependent process. In this work, we used Northern ... [more ▼]

Benign prostatic hyperplasia (BPH) is so common in elderly men that the development of adenomatous nodules in this organ can be seen as a normal age-dependent process. In this work, we used Northern blotting to compare the levels of androgen, estrogen, and insulin-like growth factor-I (IGF-I) receptor in young (age range, 23-33; n = 3), old normal (age range, 52-80; n = 3), and BPH-affected subjects (age range, 66-87; n = 15). We have also investigated in these groups the expression of genes coding for the two 5 alpha-reductases (types I and II), aromatase, IGF-I, and IGF-II. Our results show significantly increased levels of IGF mRNA in old healthy and BPH-affected subjects; the respective rises for IGF-I, IGF-II, and IGF-I receptor mRNAs were 3.0-, 2.9-, and 1.5-fold (BPH) and 2.7-, 2.4-, and 1.8-fold (old normal controls). For estrogen receptor, androgen receptor, and type I and II 5 alpha-reductase mRNAs, a marked but opposite effect was observed in adenomatous tissues only; the respective levels were 2.2-, 1.8-, 3.9-, and 1.7-fold lower than those in young adult subjects, whereas no significant differences were recorded between the two normal groups. Morphometric analysis of each tissue specimen confirmed the significantly lower epithelium/stroma ratio in adenomas compared to young or old healthy tissues. Together, these observations suggest that prostatic adenomas may result from at least two conjugate processes: one characterized by a drop in the mRNA levels of steroid hormone receptors, which might be associated with a lower epithelium/stroma ratio, and another characterized by normal aging phenomena, of which the increased production of IGFs and IGF-I receptor transcripts could be biochemical markers. [less ▲]

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See detailEvidence for Free Radical Formation During Human Kidney Transplantation
Pincemail, Joël ULg; Defraigne, Jean-Olivier ULg; Franssen, Christine ULg et al

in Free Radical Biology & Medicine (1993), 15(3), 343-8

Fourteen patients undergoing kidney transplantation were studied for evidence of the production of free radicals as assessed by the measurement of vitamin E (an index of lipid peroxidation) and of ... [more ▼]

Fourteen patients undergoing kidney transplantation were studied for evidence of the production of free radicals as assessed by the measurement of vitamin E (an index of lipid peroxidation) and of myeloperoxidase (a marker of neutrophil activation) in the systemic blood. Early (2 min) and late revascularization (30 min) of the kidney were respectively associated with a significant decrease of 35.5 and 40% of the initial level of plasma vitamin E. This consumption paralleled to the decrease of the vitamin E/total lipids ratio, a better indicator of vitamin E status. Heparin administration preceding renal artery clamping resulted in a twofold significant increase of baseline plasma myeloperoxidase (MPO) level (523 +/- 214 ng/ml). At kidney reperfusion, MPO concentration rose again and reached a maximum value of 1,653 +/- 882 ng/ml, indicating the presence of considerable neutrophil activation. A return to the baseline value was observed after 30 min of reperfusion. A short discussion about the possible origin of this MPO increase is given. Taken together, these data strongly suggest that free radical production, leading to lipid peroxidation phenomena, can occur within the early phase of kidney revascularization. Preliminary data using electron spin resonance with the spin-trapping technique strengthen this hypothesis. [less ▲]

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See detailAspects chirurgicaux de la transplantation d'organes
Meurisse, Michel ULg; Pirenne, Jacques; Bonnet, Pierre ULg

in Néphrologie Dialyse Transplantation - Livre de références - ORPADT - Volume 2 (1993)

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See detailSurgical Technique for Cardiomyoplasty and Iterative Transthoracic Biopsies in an Experimental Goat Model
Radermecker, M. A.; Fourny, J.; Bonnet, Pierre ULg et al

in European Surgical Research = Europäische Chirurgische Forschung = Recherches Chirurgicales Européennes (1993), 25(2, Mar-Apr), 110-22

Cardiomyoplasty is a new surgical procedure using transformed skeletal muscle to reinforce or substitute for the myocardium. For the purpose of studying surgical technique and investigating basic ... [more ▼]

Cardiomyoplasty is a new surgical procedure using transformed skeletal muscle to reinforce or substitute for the myocardium. For the purpose of studying surgical technique and investigating basic questions, we have developed a model of reinforcement cardiomyoplasty. Herein, we describe anesthetic management, surgical technique, and the technique for iterative transthoracic biopsies. This model has proven to be valuable in several long-term studies involving more than 30 goats. Preliminary data to ascertain the efficacy of the proposed technique are provided. [less ▲]

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See detailFlexible Technique for Multiple Organ Procurement in Rats: A Training and Research Tool in Transplantation
D'Silva, M.; Pirenne, J.; Bonnet, Pierre ULg et al

in Microsurgery (1993), 14(5), 342-9

Multiple organ procurement techniques are increasingly popular in many transplant centers. This paper describes a technique for multiorgan unit(s) explantation in rats. The procedure involves in situ ... [more ▼]

Multiple organ procurement techniques are increasingly popular in many transplant centers. This paper describes a technique for multiorgan unit(s) explantation in rats. The procedure involves in situ preliminary dissection, cold perfusion of the thoracic and abdominal organ units as separate procedures, explantation, and finally the ex situ isolation of various organ units as single and/or multiple organ combination units. The procedure is feasible, allows for flexibility in the separation of combination organ units, and is reproducible. The exercise is provided as a training and research tool for clinical and research transplant surgeons. The technique is also presented as an animal model for clinical organ sharing. [less ▲]

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See detail"Arterialization", "revascularization" , "rearterialization" - what's in a name?
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULg et al

in Transplant International (1992), (5), 121-122

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See detailRésection hépatique ex situ
Honoré, Pierre ULg; D'Silva, Milbhor; Meurisse, Michel ULg et al

in Médecine & Chirurgie Digestives (1992), 21

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See detailEndocrinology of normal and pathological development of the prostate
Bonnet, Pierre ULg; Bouffioux, Christian ULg

in Jakse, G.; Bouffioux, Christian; de Leval, Jean (Eds.) et al Benign prostatic hyperplasia: Conservative and Operative Management (1992)

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See detailOriginal lithotomy positioning for transperineal extracorporeal shockwave lithotripsy for distal ureteric calculi with Tripter X1.
Andrianne, Robert ULg; Vandeberg, Colette ULg; Bonnet, Pierre ULg et al

in European Urology (1992), 22(2), 134-6

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the ... [more ▼]

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the orientation of the semi-ellipsoid reflector) are adapted for the treatment of kidney or lumbar ureter stones. However, the elements forming the unit of treatment (the table, the C-arm and the Tripter) can be modified in such a way that focalization of stones of the lower ureter becomes possible through a perineal exposure. The aim is to avoid the pelvic bone shield while a good focalization of the stone is realized. From June 1989 to March 1991, 35 patients were treated for distal ureteric stones by ESWL in this original positioning. [less ▲]

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See detailGrowth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats.
Reiter, E.; Bonnet, Pierre ULg; Sente, B. et al

in Molecular & Cellular Endocrinology (1992), 88(1-3), 77-87

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented ... [more ▼]

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented with highly purified human prolactin (hPRL), human luteinizing hormone (hLH), porcine follicle-stimulating hormone (pFSH), and bovine growth hormone (bGH) or with saline. Quantitative analysis of RNAs shows that treatment with either PRL or GH increases significantly steady-state mRNAs levels of the following genes in the prostate: androgen receptor (AR) (respectively 3.5- and 4.8-fold above hypox controls), IGF-I (5- and 2.7-fold), and IGF-I receptor (2.9- and 2.3-fold). LH and FSH, by contrast, have negative effects on these parameters. To test whether the enhancing effect of PRL and GH on AR-mRNA abundance was followed by increased content in the protein itself, binding assays were performed with the androgen agonist [3H]R1881 (131 and 153 fmol/mg protein while hypox controls contained 110 fmol/mg protein). In addition to the well-documented presence of prolactin receptors in prostatic tissues, we have further demonstrated, by means of nuclease S1 protection assays plus dot- and Northern-blot analyses, that a GH receptor mRNA is produced in the immature rat prostate. Moreover, we observed not only strong lactogenic but also purely somatogenic binding to be occurring in the immature prostates. Finally, we have studied IGF-I mRNA content in separated epithelial/stromal cell fractions and have concluded that IGF-I expression is principally located in the prostatic stroma. Taken together, these results suggest that PRL and GH are involved in regulating AR synthesis, at least partially by direct action on the organ. In this context IGF-I appears as a paracrine factor playing a role in epithelium/stroma interactions during prostatic development. [less ▲]

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See detailRésection hépatique ex situ
Honore, Pierre ULg; D'Silva, M.; Meurisse, Michel ULg et al

in Revue Médicale de Liège (1991), 46(11), 602-6

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See detailA technique for multiorgan harvesting in rats--an educational tool in transplantation
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULg et al

in Transplantation Proceedings (1991), 23(5), 2692

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