References of "Ben Sedrine, Wafa"
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See detailEvaluation of the Simple Calculated Osteoporosis Risk Estimation (Score) in a Sample of White Women from Belgium
Ben Sedrine, Wafa ULg; Devogelaer, J. P.; Kaufman, J. M. et al

in BONE (2001), 29(4), 374-80

Identifying patients at risk of developing an osteoporosis-related fracture will continue to be a challenge. The "gold standard" for osteoporosis diagnosis is bone densitometry. However, economic issues ... [more ▼]

Identifying patients at risk of developing an osteoporosis-related fracture will continue to be a challenge. The "gold standard" for osteoporosis diagnosis is bone densitometry. However, economic issues or availability of the technology may prevent its use under a mass screening scenario. A risk assessment instrument, the "simple calculated osteoporosis risk estimation" (SCORE), has been reported to appropriately identify women likely to have low (t score < or = -2 SD) bone mineral density (BMD) and who should be referred for bone densitometry. The aim of our study is to evaluate the discriminatory performance of SCORE in a random sample of postmenopausal white women from Belgium. For this purpose, we gathered medical data on 4035 consecutive patients aged > or = 45 years, either consulting spontaneously or referred for a BMD measurement to an outpatient osteoporosis center located at the University of Liege, Belgium. BMD measurements, using dual-energy X-ray absorptiometry (DXA) technology, were taken at the hip (total and neck) and lumbar spine (L2-4). At the recommended cutoff point of 6, SCORE had a sensitivity of 91.5% to detect low BMD at any of the measured sites, a specificity of 26.5%, a positive predictive value of 52.8%, and a negative predictive value of 77.7%. According to SCORE, 18% of the patients would not be recommended for densitometry. Among these, 10.9% were misclassified as they had osteoporosis (t score < or = -2.5 SD) at one or more of the sites investigated. The negative predictive errors of SCORE, when failing to detect osteoporosis, were only 1% for the total hip, 3.2% for the femoral neck, and 8.8% for the lumbar spine. We conclude that, notwithstanding the high values of sensitivity, SCORE specificity is too low to be useful as a diagnostic tool for screening patients at high risk to later develop osteoporosis. Nevertheless, from a resource allocation perspective, this instrument can be used with relative confidence to exclude patients who do not need a BMD measurement, and would therefore provide an opportunity to realize substantial cost savings in comparison to a mass screening strategy. [less ▲]

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See detailOn Conducting Burden-of-Osteoporosis Studies: A Review of the Core Concepts and Practical Issues. A Study Carried out under the Auspices of a Who Collaborating Center
Ben Sedrine, Wafa ULg; Radican, L.; Reginster, Jean-Yves ULg

in Rheumatology (2001), 40(1), 7-14

Osteoporosis is a problem that is relevant to public health from the clinical, economic and social viewpoints. Except in a handful of industrialized countries, there is a considerable void in our ... [more ▼]

Osteoporosis is a problem that is relevant to public health from the clinical, economic and social viewpoints. Except in a handful of industrialized countries, there is a considerable void in our knowledge of the magnitude of the problem. By exploring both the epidemiological and the economic impact of osteoporosis and the fractures associated with it in a particular country, studies of the 'burden of illness' (BOI) can fill that void. BOI analysis raises many questions at both the conceptual and the practical level. The purpose of this paper is to review the methodology underlying analyses of this type, to discuss its limitations and to provide a general format to improve their implementation in the field of osteoporosis. Investigators involved in BOI analysis should be very clear and explicit regarding the methods they adopt, so that studies in different countries can be interpreted and compared appropriately by interested parties. [less ▲]

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See detailA simple clinical tool to identify Asian women with osteoporosis
Lou, SQ; Koh, L; Yang, BY et al

in Journal of Rheumatology (2001), 28(S63), 26

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See detailScreening for postmenopausal osteoporosis in Belgium in a primary care setting
Goemaere, S; Laurier, D; Hoet, H et al

in Clinical Rheumatology (2001), 20

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See detailInterest of a prescreening questionnaire to reduce the cost of bone densitometry
Ben Sedrine, Wafa ULg; Broers, P; Devogelaer, JP et al

in Clinical Rheumatology (2001), 20

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See detailEvaluation of the simple calculated osteoporosis risk estimation in a sample of Caucasian women from Belgium
Ben Sedrine, Wafa ULg; Devogelaer, JP; Kaufman, JM et al

in Clinical Rheumatology (2001), 20

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See detailValidation of a simple clinical tool to identify Asian women with osteoporosis
Rajatanavin, R; Tsai, KS; Chan, SP et al

in BONE (2001), S28

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See detailApplying a simple clinical tool to identify osteoporosis among Japanese women
Fujiwara, S; Masunari, N; Suzuki, G et al

in BONE (2001), S28

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See detailDevelopment of a predictive model and a risk assessment instrument to facilitate diagnosis of low bone mass in postmenopausal women
Ben Sedrine, Wafa ULg; Chevalier, Th; Micheletti, MC et al

in Arthritis and Rheumatism (2001), 44(1570), 314

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See detailKorean experience with OSTA risk index for osteoporosis : a validation study
Ben Sedrine, Wafa ULg; Park, HM; Reginster, Jean-Yves ULg

in Arthritis and Rheumatism (2001), 44(1246), 260

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See detailUsing the OSTA index to identify women at risk of osteoporosis : a validation study in China
Ben Sedrine, Wafa ULg; Huang, Q; Reginster, Jean-Yves ULg

in Arthritis and Rheumatism (2001), 44(1233), 258

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See detailA simple table based on age and weight identifies Asian women at risk of osteoporosis
Ben Sedrine, Wafa ULg; Lin Liu, G; Reginster, Jean-Yves ULg

in Arthritis and Rheumatism (2001), 44(1232), 258

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See detailValidation of the OSTA risk index in Japanese women
Ben Sedrine, Wafa ULg; Fujiwara, S; Masunari, N et al

in Arthritis and Rheumatism (2001), 44(1231), 258

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See detailInterest of the simple calculated osteoporosis risk estimation (SCORE) tool for a more rational use of bone densitometry
Ben Sedrine, Wafa ULg; Devogelaer, JP; Kaufman, JM et al

in Value in Health (2000, March), 3

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See detailThe simple calculated osteoporosis risk estimation (SCORE) does not allow identification of Belgian women with a high risk of osteoporosis
Ben Sedrine, Wafa ULg; Devogelaer, Jean-Pierre; Kaufman, Jean-Marc et al

in Value in Health (2000, March), 3

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