References of "Beckers, Albert"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailGenetic analysis in young patients with sporadic pituitary macroadenomas:Beside AIP don't forget MEN1 genetic analysis.
Cuny, Thomas; Pertuit, Morgane; Sahnoun-Fathallah, Mouna et al

in European Journal of Endocrinology (2013)

CONTEXT: germline mutations in the AIP gene have been identified in young patients (age </= 30 years old) with sporadic pituitary macroadenomas. Otherwise, there are few data concerning the prevalence of ... [more ▼]

CONTEXT: germline mutations in the AIP gene have been identified in young patients (age </= 30 years old) with sporadic pituitary macroadenomas. Otherwise, there are few data concerning the prevalence of MEN1 mutations in such population. OBJECTIVE: We assessed the prevalence of both AIP and MEN1 genetic abnormalities (mutations and large gene deletions) in young patients (age </= 30 years old) diagnosed with sporadic and isolated macroadenoma, without hypercalcemia and/or MEN1-associated lesions. DESIGN: The entire coding sequences of AIP and MEN1 were screened for mutations. In cases of negative sequencing screening, multiplex ligation-dependent probe amplification was performed for the detection of large genetic deletions. PATIENTS AND SETTINGS: 174 patients from Endocrinology Departments of 15 French University Hospital Centers were eligible for this study. RESULTS: 21/174(12%) patients had AIP (n=15, 8.6%) or MEN1 (n=6, 3.4%) mutations. In pediatric patients (age </= 18 years old), AIP/MEN1 mutation frequency reached nearly 22% (n=10/46). AIPmut and MEN1mut were respectively identified in 8/79 (10.1%) and 1/79 (1.2%) somatotropinoma patients; they each accounted for 4/74 (5.4%) prolactinoma patients with mutations. Half of patients (n=3/6) with gigantism displayed mutations in AIP. Interestingly, 4/12 (33%) patients with non-secreting adenomas bore either AIP or MEN1 mutations, whereas none of the 8 corticotroph-adenomas and a single thyrotropinoma case had mutations. No large gene deletions were observed in sequencing-negative patients. CONCLUSION: mutations in MEN1 can be of significance in young patients with sporadic isolated pituitary macroadenomas, particularly prolactinomas, and together with AIP, we suggest genetic analysis of MEN1 in such population. [less ▲]

Detailed reference viewed: 40 (5 ULg)
Full Text
See detailA prospective study of cardiac valvular status in patients treated with cabergoline for endocrine disease
VROONEN, Laurent ULg; LANCELLOTTI, Patrizio ULg; Tome, M et al

in Symposium "Perspectives in Endocrinology" - Congresses Highlights 2012: ECE Firenze, ENDO Houston, ESPE Leipzig, SFE Toulouse, IWMEN Liège (2013)

Detailed reference viewed: 28 (4 ULg)
Full Text
See detailThe role of tyrosin kinase inhibitors in a MEN2B patient with metastatic medullary thyroid carcinoma
Tome, M; Tomas, M-H; VROONEN, Laurent ULg et al

in Symposium "Perspectives in Endocrinology" - Congresses Highlights 2012: ECE Firenze, ENDO Houston, ESPE Leipzig, SFE Toulouse, IWMEN Liège (2013)

Detailed reference viewed: 29 (2 ULg)
Full Text
Peer Reviewed
See detailMalabsorption des hormones thyroïdiennes... ou simple manque de compliance ?
Benoit, Arnaud ULg; BOUQUEGNEAU, Antoine ULg; PETROSSIANS, Patrick ULg et al

in Revue Médicale de Liège (2013), 68(3), 118-121

Detailed reference viewed: 60 (1 ULg)
See detailRadiotherapy : controversy
Beckers, Albert ULg

Scientific conference (2012, November)

Detailed reference viewed: 17 (3 ULg)
Full Text
Peer Reviewed
See detailExpression et localisation spatio-temporelle de KISS1 et de son récepteur KISSR dans le placenta normal et pathologique.
VALDES SOCIN, Hernan Gonzalo ULg; Munaut, Carine ULg; CHAVEZ, Viviana ULg et al

Poster (2012, October)

Objectif : Etudier l’expression de KISS1 (métastatine) et de son récepteur KISS1R lors de la grossesse normale et pathologique. Matériels et méthodes : Nous avons étudié la localisation de KISS1 et KISS1R ... [more ▼]

Objectif : Etudier l’expression de KISS1 (métastatine) et de son récepteur KISS1R lors de la grossesse normale et pathologique. Matériels et méthodes : Nous avons étudié la localisation de KISS1 et KISS1R par immunohistochimie dans des placentas normaux (1 er et 3 ème trimestre). Par RT-PCR quantitative, nous avons évalué le niveau d’expression des ARNm dans les placentas et les lits placentaires correspondants. Les niveaux d’expression de ARNm ont été comparés entre les grossesses normales (GN, n=13) et les grossesses spathologiques Prééclampsiques -PE-, n=17 et retard de croissance intrautérine -RCIU-, n=9). Résultats : Au premier trimestre des GN, KISS1 est majoritairement localisé dans les syncitiotrophoblastes, alors que KISS1R est détecté dans le mesenchyme villositaire. Au cours du troisième trimestre, KISS1 est uniquement localisé dans le syncitiotrophoblaste au contact avec la décidue et dans le mésenchyme villositaire et KISS1R est détecté dans le trophoblaste extra-villeux ainsi que dans quelques cellules de la décidue. Les analyses par RT-PCR mettent en évidence une expression plus importante des ARNm de KISS1 (p<0,001) et de KISS1R (p=0.039) dans les placentas (GN,PE et RCIU) par rapport aux lits placentaires correspondants. Les niveaux d’expression de KISS1 et KISS1R ne sont pas, cependant, significativement modulés dans les grossesses pathologiques. Conclusions : Par immunohistochimie, nos résultats indiquent une expression spatiotemporelle différente pour KISS1 et KISS1R entre le 1 er et 3 ème trimestre des grossesses normales. Nous n’avons pas mis en évidence de modulation de l’expression des ARNm dans les grossesses pathologiques. [less ▲]

Detailed reference viewed: 37 (9 ULg)
See detailFamilial Pituitary Syndromes
Beckers, Albert ULg

Scientific conference (2012, October)

Detailed reference viewed: 6 (3 ULg)
See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

Scientific conference (2012, October)

Detailed reference viewed: 4 (2 ULg)
Full Text
See detailFamilial Isolated Pituitary Adenomas
Beckers, Albert ULg

in Syllabus : Canadian Diabetes association : Professional Conference and Annual Meetings (2012, October)

Detailed reference viewed: 11 (4 ULg)
See detailFamilial Pituitary Syndromes
Beckers, Albert ULg

in 12th ESE PostGraduate Course in Clinical Endocrinology - Abstract book (2012, October)

Detailed reference viewed: 16 (4 ULg)
See detailEpidemiology and genetics of FIPA
Beckers, Albert ULg

in 15th annual Canadian Society of Endocrinology and metabolism - Abstract book (2012, October)

Detailed reference viewed: 10 (4 ULg)
See detailRational use of genetic testing in patients with pituitary adenomas and their families
Beckers, Albert ULg

Scientific conference (2012, September 05)

Detailed reference viewed: 16 (3 ULg)
Full Text
Peer Reviewed
See detailThe coexistence of a pituitary adenoma and pheochromocytoma (a case report)
Filipponi, S; Rostomyan, Liliya ULg; VROONEN, Laurent ULg et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

Detailed reference viewed: 25 (4 ULg)
Full Text
See detailThe clinical and genetic characteristics of patients with gigantism
Rostomyan, Liliya ULg; Daly, Adrian ULg; Tichomirova, M et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

Detailed reference viewed: 29 (2 ULg)
Full Text
See detailClinical and genetic studies in patients with Pituitary/Parathyroid variant of MEN1 without MEN1 gene mutation : the French GENEM collaborative study
VALDES SOCIN, Hernan Gonzalo ULg; Burlacu, C; Delemer, B et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

Detailed reference viewed: 19 (1 ULg)
Full Text
See detailErythropoiesis in acromegaly : effect of GH or IGF-1 ? Data from the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal für Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3), 45

Detailed reference viewed: 23 (4 ULg)
Full Text
See detailGH or IGF-1 : which one is raising blood glucose ? Hints from the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal of Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3),

Detailed reference viewed: 17 (1 ULg)
Full Text
See detailAge, GH and tumor size : the triangular relation in acromegaly. Data from the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal für Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3), 43

Detailed reference viewed: 26 (7 ULg)
Full Text
See detailAging of the newly diagnosed acromegalic patients : data frome the LAS (Liege Acromegaly Survey)
PETROSSIANS, Patrick ULg; Zacharieva, S; Chanson, P et al

in Journal für Klinische Endokrinologie und Stoffwechsel (2012, September), 5(3), 33

Detailed reference viewed: 19 (3 ULg)
Full Text
See detailThe thyrogastric syndrome : an under diagnosed etiology for acquired gastric neuroendocrine tumors. A case report
VALDES SOCIN, Hernan Gonzalo ULg; LOLY, Jean ULg; GAST, Pierrette ULg et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

Detailed reference viewed: 48 (10 ULg)