Effect of exercise on innate immunity in horses

in Proceedings of the 6th Congress of the European College of Equine Internal Medicine (ECEIM): ACVIM, Le Touquet France (2013)

Investigation of the effect of exercise on the innate immunity in horses

Poster (2012, October 19)

Characterization of T-helper lymphocytes in peripheral blood and bronchoalveolar lavage of healthy horses with recurrent airway obstruction

Poster (2012)

Assessing fitness in endurance horses

in Canadian Veterinary Journal = Revue Vétérinaire Canadienne (2012), 53

A field test and a standardized treadmill test were used to assess fitness in endurance horses. These tests discriminated horses of different race levels: horses participating in races of 120km and more ... [more ▼]

A field test and a standardized treadmill test were used to assess fitness in endurance horses. These tests discriminated horses of different race levels: horses participating in races of 120km and more showed higher values of VLA4 (velocity at which blood lactate reached 4 mmol/L) and V200 (velocities at which heart rates reached 200 beats per min) than horses of lower race levels. [less ▲]

Les tests de bronchoprovocation à la métacholine dans le diagnostic de l'hyperréactivité bronchique chez le cheval asymptomatique

in Proceedings de la 38ème Journée de la Recherche Equine (2012)

The clinical examination and the ancillary tests at the disposal from the veterinarian may be poor diagnostics in horses suffering from subclinical inflammatory airway disease or in clinical remission of ... [more ▼]

The clinical examination and the ancillary tests at the disposal from the veterinarian may be poor diagnostics in horses suffering from subclinical inflammatory airway disease or in clinical remission of recurrent airway obstruction (RAO). The objective of this study was to determine whether the methacholine bronchoprovocation test -which is daily used for diagnosis of asymptomatic human asthma- may be used as an applicable and repeatable method for the diagnosis of an increased susceptibility to bronchospasm in horses. The test, realised on 8 horses (6 with RAO history and 2 controls) presents a good feasibility and significant repeatability. Dust exposure increased the bronchoreactivity, while it did not affect other clinical and functional parameters or inflammatory markers. In the future, the bronchoprovocation test could therefore find its place in clinicat practice for the detection of asymptomatic horses which are susceptible to develop bronchospasm in poor environmental conditions. [less ▲]

Le microdamier d’expression : un outil performant dans la compréhension de la réponse

in Annales de Médecine Vétérinaire (2011), 154

Malgré de multiples études, les interrelations entre l’exercice, le stress et la réponse immune sont peu définies. Or, la compréhension de ces interrelations pourrait jouer un rôle très important dans ... [more ▼]

Malgré de multiples études, les interrelations entre l’exercice, le stress et la réponse immune sont peu définies. Or, la compréhension de ces interrelations pourrait jouer un rôle très important dans l’amélioration de la santé et des résultats sportifs des athlètes. En effet, l’exercice peut être reconnu comme un stress. Il induit des modifications de l’équilibre homéostatique qui peuvent à leur tour altérer la réponse immunitaire de l’hôte et donc sa susceptibilité aux maladies. L’adrénaline est la molécule essentielle de tout processus de stress. La technologie des microdamiers, outil majeur d’investigation transcriptomique, permet l’étude de l’expression génique de l’ensemble du génome. Son utilisation devrait donc permettre de mieux caractériser et définir les interrelations entre l’exercice, le stress et la réponse immune. Cette revue recense les interrelations connues entre la réponse immune à un stress adrénergique d’une part et la réponse immune à l’exercice d’autre part. Elle considère en outre la contribution potentielle des microdamiers à une meilleure compréhension des effets d’un stress, et plus particulièrement celui lié à l’exercice, sur l’immunité. [less ▲]

Sub-clinical diseases underlying poor performance in endurance horses: diagnostic methods and predictive tests

Poster (2011)

Comparison of overground and high-speed treadmill endoscopy for the diagnostic of upper airway dynamic obstructions in saddle horses

Poster (2011)

Applied training physiology

in 5th Edition of the European Equine Health & Nutrition Congress (5th EEHNC) (2011)

Subclinical diseases underlying poor performance in endurance horses: diagnostic methods and predictive tests.

in Veterinary Record : Journal of the British Veterinary Association (2011), 169(6), 154

Thirty-eight endurance horses underwent clinical and ancillary examinations, including haematological and biochemical evaluation, standardised exercise tests both on a treadmill and in the field, Doppler ... [more ▼]

Thirty-eight endurance horses underwent clinical and ancillary examinations, including haematological and biochemical evaluation, standardised exercise tests both on a treadmill and in the field, Doppler echocardiography, impulse oscillometry, video endoscopy and collection of respiratory fluids. All of the examined poorly performing horses were affected by subclinical diseases, and most of them had multiple concomitant disorders. On the contrary, the well-performing horses were free of any subclinical disease. The most frequently diagnosed diseases were respiratory disorders, followed by musculoskeletal and cardiac problems. Poor performers exhibited lower speeds at blood lactate concentration of 4 mmol/l (VLA4) and at heart rates of 160 (V160) and 200 bpm (V200) on the treadmill and in the field, as well as slower recovery of heart rate. [less ▲]