References of "Angenot, Luc"
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See detailContribution à l'étude pharmacognostique de la passiflore
Brasseur, Thierry; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1984), 39(1), 15-22

Review of botanical, phytochemical and pharmacological data about Passiflora incarnata L. and two possible falsifications: Passiflora edulis SIMS and Passiflora caerulea L is presented.A reliable ... [more ▼]

Review of botanical, phytochemical and pharmacological data about Passiflora incarnata L. and two possible falsifications: Passiflora edulis SIMS and Passiflora caerulea L is presented.A reliable identification by TLC is also described. [less ▲]

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See detailA propos du Drosera peltata et de la standardisation de la teinture de Drosera
Leclercq, Joëlle; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1984), 39(5), 269-274

The authors describe Drosera peltata , an Asiatic species newly appeared on the European marke, and give a method of identification and quantitative determination of plumbagin to standardize the drug and ... [more ▼]

The authors describe Drosera peltata , an Asiatic species newly appeared on the European marke, and give a method of identification and quantitative determination of plumbagin to standardize the drug and mainly the tincture that is used in pharmaceutical preparations against cough. [less ▲]

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See detailA propos des substances toxiques recherchées dans les poudres à éternuer
Libon, Michel; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1984), 39(4), 233-237

Poisoning due to sneezing powders made it necessary to control commercialized samples to detect possible presence of toxic products such as poisonous plants ( Veratrum sp., Helleborus viridis, Quillaja sp ... [more ▼]

Poisoning due to sneezing powders made it necessary to control commercialized samples to detect possible presence of toxic products such as poisonous plants ( Veratrum sp., Helleborus viridis, Quillaja sp....) or synthetic chemicals (benzidine, dianisidine, o-nitrobenzaldehyde). The authors give a summary of analytical and toxicological data. results of experiments on samples collected in belgium are also provided. [less ▲]

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See detailAntimitotic activity of strychnopentamine, a bisindolic alkaloid
Tits, Monique ULg; Desaive, Claude ULg; Marnette, J. M. et al

in Journal of Ethnopharmacology (1984), 12

Strychnopentamine has been tested for its cytotoxicity and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine ... [more ▼]

Strychnopentamine has been tested for its cytotoxicity and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine group increases the antimitotic activity of this type of alkaloids. [less ▲]

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See detailEtude complémentaire de la cytotoxicite de la mélinonine F, alcaloide dérive de la beta-carboline
Bassleer, Roger ULg; Marnette, J. M.; Wiliquet, P. et al

in Planta Medica (1983), 49(11), 158-161

The cellular effects of melinonine F, an alkaloid isolated from STRYCHNOS MELINONIANA (South America) and STRYCHNOS USAMBARENSIS (Central Africa), are analysed in cancer or normal cells in culture. A ... [more ▼]

The cellular effects of melinonine F, an alkaloid isolated from STRYCHNOS MELINONIANA (South America) and STRYCHNOS USAMBARENSIS (Central Africa), are analysed in cancer or normal cells in culture. A cytotoxic action is noted in both types of cells, at least for relatively high concentrations. These effects are probably due to interaction of the drug with chromatin. Physico-chemical analysis demonstrates partial intercalation of melinonine F on pure DNA IN VITRO. [less ▲]

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See detailLa guattegaumerine, nouvel alcaloide bisbenzylisoquinoleinique de Guatteria gaumeri
Dehaussy, H.; Tits, Monique ULg; Angenot, Luc ULg

in Planta Medica (1983), 49(9), 25-7

The aqueous-alcoholic extract of the bark of GUATTERIA GAUMERI (Mexican Annonaceae) is used for the treatment of cholelithiasis and hypercholesterolemia. Therefore it seems very interesting to perform a ... [more ▼]

The aqueous-alcoholic extract of the bark of GUATTERIA GAUMERI (Mexican Annonaceae) is used for the treatment of cholelithiasis and hypercholesterolemia. Therefore it seems very interesting to perform a phytochemical study of this drug in order to know its composition and to determine, if possible, all the active principles. We describe now the isolation of the main alkaloid named guattegaumerine. This new bisbenzylisoquinoline alkaloid has been assigned structure 1, on the basis of spectroscopic, chemical and chromatographic evidence. [less ▲]

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See detail12'-Hydroxystrychnobiline, nouvel alcaloïde bisindolinique du Strychnos variabilis
Tits, Monique ULg; Angenot, Luc ULg; Tavernier, Dirk

in Journal of Natural Products (1983), 46(5), 638-645

12'-hydroxystrychnobiline, a new unsymmetrical bisindole alkaloid, was isolated from the root barks of Strychnos variabilis. Its structure was established by acid hydrolysis and by spectral analysis ... [more ▼]

12'-hydroxystrychnobiline, a new unsymmetrical bisindole alkaloid, was isolated from the root barks of Strychnos variabilis. Its structure was established by acid hydrolysis and by spectral analysis, especially by 1H-nmr at 360MHz. We compare its absolute stereochemistry with that of other alkaloids that contain an oxazine ring. [less ▲]

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See detailIsolement et structure de trois bases anhydronium du Strychnos usambarensis du Rwanda
Caprasse, Maryse; Coune, Claude; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1983), 38(3), 135-139

Three anhydronium bases have been isolated by DCC Chromatography. They were identified as melinonine F, dihydr-5,6 flavopereirine and the novel normelinonine F through their spectroscopic data and ... [more ▼]

Three anhydronium bases have been isolated by DCC Chromatography. They were identified as melinonine F, dihydr-5,6 flavopereirine and the novel normelinonine F through their spectroscopic data and comparison with authentic samples. [less ▲]

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See detailDidéhydro-16,17 isostrychnobiline, nouvel alcaloÏde bisindolinique asymétrique du Strychnos variabilis
Tits, Monique ULg; Angenot, Luc ULg; Tavernier, Dirk

in Journal de Pharmacie de Belgique (1983), 38(5), 241-245

We describe a new asymmetrical bisindole alkaloid, 16,17-didehydroisostrychnobiline, that was isolated by reverse phase liquid chromatography from the root barks of Strychnos variabilis. Its structure was ... [more ▼]

We describe a new asymmetrical bisindole alkaloid, 16,17-didehydroisostrychnobiline, that was isolated by reverse phase liquid chromatography from the root barks of Strychnos variabilis. Its structure was elucidated from spectral analysis and by acid hydrolysis. Its stereochemistry was established by 300 MHz 1H NMR spectroscopy [less ▲]

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See detailDeux nouveaux alcaloïdes quaternaires isolés à partir des feuilles du Strychnos usambarensis GILG du Rwanda: Nb-méthyl hydroxy-10 et hydroxy-11 usambarines
Caprasse, Maryse; Tavernier, Dirk; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1983), 38(4), 211-218

Two new isomeric bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. They are phenolic dimers of the "usambarine (usambarane) type" and correspond to the Nb-methyl-derivatives of ... [more ▼]

Two new isomeric bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. They are phenolic dimers of the "usambarine (usambarane) type" and correspond to the Nb-methyl-derivatives of 10- and 11-hydroxy-usambarine. The structure elucidation and the stereochemistry of these molecules are discussed from their spectroscopic properties (UV,IR,MS, CD , NMR). TLC comparison with quaternarized 10- and 11-hydroxy-usambarine provides a corroborative structural proof. The separation of the two alkaloids by "DCCC" (Droplet Counter current Chromatography) gives a new example of the application of this suitable technique for the separation of polar coumpounds that it is always very difficult to purify and separate. [less ▲]

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See detailComposition chimique de la fumée de tabac
Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1983), 38(3), 172-180

The tobacco plant has been the object of extensive basic research about its genetic, culture, biochemistry and postharvest metabolism. In addition , much is known of its pyrolysis products and the ... [more ▼]

The tobacco plant has been the object of extensive basic research about its genetic, culture, biochemistry and postharvest metabolism. In addition , much is known of its pyrolysis products and the conditions that affect the formation of these products. Tobacco smaoke is a concentrated aerosol of liquid particles suspended in an atmosphere consisting mainly of nitrogen, oxygen and CO2. While the precise chemical composition of the particular and gaseous phases is depended on the characteristics of commercial tobacco and the manner in which it is smoked, both phases contained tens of hundreds of individual constituents. Notable among potentially hazardous constituents of smoke are tar (mainly benzopyrene) nicotine, HCN, acrolein, N-nitrosamines, cadmium and polonium 210. recent advances in tobacco science make it possible to develop a safer tobacco that delivers undesirable smoke compounds at levels that are below the old values, but these results are biologically uninterpretable at present. [less ▲]

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See detailRecherches actuelles et perspectives d'avenir des services pharmaceutiques de l'Université de liège
Lapière, Charles-Léon; Angenot, Luc ULg; Bosly, Jean et al

in Angenot, Jean-François (Ed.) La Pharmacie et l'Art de guérir au Pays de Liège des origines à nos jours (1983)

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See detailEffets de trois Alcaloides Extraits du Strychnos usambarensis sur des Cellules Cancereuses en Culture
Bassleer, Roger ULg; Gillet, Marie-Claire ULg; Massart, B. et al

in Planta Medica (1982), 45(6), 123-6

The cellular effects of three alkaloids isolated from STRYCHNOS USAMBARENSIS (melinonine F, strychnofoline, 18-19-dihydro-usambarine) are analysed by cytological methods in experimental animal tumours ... [more ▼]

The cellular effects of three alkaloids isolated from STRYCHNOS USAMBARENSIS (melinonine F, strychnofoline, 18-19-dihydro-usambarine) are analysed by cytological methods in experimental animal tumours cultivated IN VITRO (B 16 mouse melanoma cells, mouse Ehrlich tumour cells ELT, HW 165 rat hepatoma). Under some experimental conditions, a certain degree of antimitotic activity is demonstrated. [less ▲]

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See detailRMN C13 des alcaloïdes des Strychnos : les dérivés de l'usambarine, de la sarpagine et de la mavacurine
Coune, Claude; Tits, Monique ULg; Angenot, Luc ULg

in Journal de Pharmacie de Belgique (1982), 37(3), 189-194

13C NMR spectra of seven tertiary and quaternary indole alkaloids are recorded and the signals assigned. The data permit classification and identification of these alkaloids. Moreover the similarity of ... [more ▼]

13C NMR spectra of seven tertiary and quaternary indole alkaloids are recorded and the signals assigned. The data permit classification and identification of these alkaloids. Moreover the similarity of nigritanin and 18,19-dihydrousambarine have been confirmed by this study [less ▲]

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See detailContribution à l'étude des propriétés insecticides et chimiques d'Eucalyptus saligna du Zaïre
Kambu, Kabangu; Di Phanzu, N.; Coune, Claude et al

in Plantes Médicinales et Phytothérapie (1982), 16(1), 34-38

The oil of Eucalyptus saligna ( collected on the campus of the University at Kinshasa ( Zaire or Democratic Republic of Congo) has insecticidal properties (against flies, lice, mosquitoes, bed-bugs, black ... [more ▼]

The oil of Eucalyptus saligna ( collected on the campus of the University at Kinshasa ( Zaire or Democratic Republic of Congo) has insecticidal properties (against flies, lice, mosquitoes, bed-bugs, black-beetles) and contains mainly : 1,8-cineol, alpha-pinene,borneol, alpha-terpineol and linalol. [less ▲]

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See detailApplications des techniques spectrométriques dans le domaine des produits naturels...
Angenot, Luc ULg; Coune, Claude

Scientific conference (1981, October 19)

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See detailLes Alcaloides majoritaires du Strychnos scheffleri du Zaire
Caprasse, M.; Angenot, Luc ULg

in Planta Medica (1981), 42(8), 364-70

Leaves and stem barks of S. SCHEFFLERI G ILG afforded eight dihydroindole alkaloids. Four tertiary monomers (O-methyl Na-acetylstrychnosplendine, Na-acetylstrychnosplendine, strychnobrasiline and ... [more ▼]

Leaves and stem barks of S. SCHEFFLERI G ILG afforded eight dihydroindole alkaloids. Four tertiary monomers (O-methyl Na-acetylstrychnosplendine, Na-acetylstrychnosplendine, strychnobrasiline and strychnofendlerine) have been isolated from leaf material while stem barks yielded one tertiary monomer (desacetylisoretuline), one tertiary symmetrical dimer (bis-nordihydrotoxiferine) and two quaternary monomers (mavacurine and fluorocurine). [less ▲]

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See detailLes alcaloides quaternaires majoritaires du Strychnos variabilis du Zaire
Tits, Monique ULg; Franz, Michel ULg; Tavernier, D. et al

in Planta Medica (1981), 42(8), 371-4

Two quaternary alkaloids have been isolated from the root barks of STRYCHNOS VARIABILIS collected in Zaire. The structure of these alkaloids (mavacurine and fluorocurine) could be deduced from spectral ... [more ▼]

Two quaternary alkaloids have been isolated from the root barks of STRYCHNOS VARIABILIS collected in Zaire. The structure of these alkaloids (mavacurine and fluorocurine) could be deduced from spectral data: UV, MS, IR and (1)H NMR. Moreover, the stereochemistry could be assigned by (1)H NMR at 360 MHz. [less ▲]

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