References of "Amory, Hélène"
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See detailComparative Pharmacokinetics of Two Intravenous Administration Regimens of Tiludronate in Healthy Adult Horses and Effects on the Bone Resorption Marker Ctx-1
Delguste, Catherine ULg; Amory, Hélène ULg; Guyonnet, J. et al

in Journal of Veterinary Pharmacology & Therapeutics (2008), 31(2), 108-16

Bioavailability and pharmacological effects of tiludronate were compared when administered as an intravenous (i.v.) bolus at a dosage of 0.1 mg/kg body weight (b.w.) once daily for 10 consecutive days ... [more ▼]

Bioavailability and pharmacological effects of tiludronate were compared when administered as an intravenous (i.v.) bolus at a dosage of 0.1 mg/kg body weight (b.w.) once daily for 10 consecutive days (group 1, n = 6) and as a single constant rate infusion (CRI) at a total dose of 1 mg/kg b.w. (group 2, n = 6) in healthy adult horses. Tiludronate and carboxy-terminal cross-linking telopeptide of type I collagen (CTX-1) were measured in plasma and urine. There was no statistically significant difference in area under the curve (AUC) and clearance (Cl) between the two groups. Bioavailability of the CRI was 103% (not significantly different) that of the 10 daily i.v. bolus doses. Cumulative urine tiludronate excretion could not be compared between groups because of poor sensitivity of the assay in urine. Plasma and urine CTX-1 levels were not different between groups throughout the study. However, interindividual variations were greater in group 1 than in group 2. A significant decrease in CTX-1 levels was observed in plasma after the first administration in group 1, but not in urine; while in group 2, a significant decrease in CTX-1 concentrations was observed after treatment in both plasma and urine. In conclusion, both dosage regimens of tiludronate produced similar plasma exposure and pharmacological effects in adult healthy horses. [less ▲]

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See detailThe Composition of the Inflammatory Infiltrate in Three Cases of Polyneuritis Equi
Van Galen, Gaby ULg; Cassart, Dominique ULg; Sandersen, Charlotte ULg et al

in Equine Veterinary Journal (2008), 40(2), 185-8

Polyneuritis equi (PNE) is a rare neurological disease in the horse. Because of the suspicion in PNE of a T-lymphocyte mediated immune response against the myelin, the objective of this study was to ... [more ▼]

Polyneuritis equi (PNE) is a rare neurological disease in the horse. Because of the suspicion in PNE of a T-lymphocyte mediated immune response against the myelin, the objective of this study was to determine the composition of the inflammatory infiltrate in the involved nerves of 3 horses with PNE, studied retrospectively. T-lymphocytes were demonstrated in the lesions, which suggests a T-lymphocyte mediated immune response against myelin. In addition, the presence of B-lymphocytes indicated a local production of antibodies. More research, involving a prospective study, is needed to determine whether the T-lymphocytes are cytotoxic or T-helper lymphocytes. [less ▲]

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See detailEffects of intravenous lidocaïne in healthy adult horses.
Amory, Hélène ULg; Lopez Arevaldo, Diégo; Maes, An et al

Poster (2008, January)

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See detailEffect of acepromazine on whole blood viscosity in horses
Sandersen, Charlotte ULg; Serteyn, Didier ULg; Dringenberg, Bernhard et al

in Proceedings of the AVA Spring Meeting (2008)

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See detailApproche diagnostique des myopathies chez le cheval
Van Galen, Gaby ULg; Serteyn, Didier ULg; Amory, Hélène ULg et al

in Le nouveau Praticien vétérinaire équine (2008), 15

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See detailVegetative endocarditis in the horse: retrospective study
Porter, Sarah ULg; Saegerman, Claude ULg; Van Galen, Gaby ULg et al

in Journal of Veterinary Internal Medicine (2008), 22(6), 1411-1416

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See detailElaboration of a PK/PD model of tiludronate in horses: a preliminary study
Delguste, Catherine ULg; Doucet, M; Lepage, O et al

Report (2008)

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See detailPhysiopathology and therapy of chronic heart failure in the equine species
Amory, Hélène ULg; Deleuze, Stefan ULg; Sandersen, Charlotte ULg

in Proceedings of the Second Resident Meeting of the European College of Equine Internal medicine (ECEIM) (2008)

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See detailCushing et syndrome métabolique équin
Amory, Hélène ULg

in Proceedings of the 25th Annual Congress of the Belgian Equine Practitioners Society (BEPS) (2008)

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See detailMorphological echocardiographic measurements: reference values as a function of body size in equids
Al Haidar, A; Sandersen, Charlotte ULg; Van Erck, Emmanuelle et al

Poster (2008)

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See detailDifferential diagnosis of equine systolic murmurs
Amory, Hélène ULg

in In the Proceedings of the Voorjaardagen Congress (2008)

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See detailBiomarkers of heart disease
Amory, Hélène ULg; Deleuze, Stefan ULg; Sandersen, Charlotte ULg

in Proceedings of the Second Resident Meeting of the European College of Equine Internal medicine (ECEIM) (2008)

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See detailDiagnostiquer et traiter les endocardites chez le cheval.
Amory, Hélène ULg

in Nouveau Praticien Vétérinaire Equine (2008), 5

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See detailIntérêt de la troponine sérique en tant que marqueur d’une atteinte du myocarde en médecine vétérinaire
Sandersen, Charlotte ULg; Remy, Benoit; Olejnik, Dorine ULg et al

in Annales de Médecine Vétérinaire (2008)

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See detailElaboration of a PK/PD model of tiludronate in horses: a preliminary study
Delguste, Catherine ULg; Doucet, Michèle; Lepage, Olivier M et al

Report (2008)

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See detailAtypical myopathy: new insights into the pathophysiology, prevention and management of the condition
Van Galen, Gaby ULg; Serteyn, Didier ULg; Amory, Hélène ULg et al

in Equine Veterinary Education (2008), 20(5), 234-238

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See detailTetanus in the equine species: a retrospective study of 31 cases.
Van Galen, Gaby ULg; Delguste, Catherine ULg; Sandersen, Charlotte ULg et al

in Tijdschrift voor Diergeneeskunde (2008), 133(12), 512-7

BACKGROUND: Few studies exist about factors affecting the outcome of horses with tetanus. ANIMALS: 31 equids (30 horses and 1 donkey) with a clinical diagnosis of tetanus admitted to the Equine Clinic of ... [more ▼]

BACKGROUND: Few studies exist about factors affecting the outcome of horses with tetanus. ANIMALS: 31 equids (30 horses and 1 donkey) with a clinical diagnosis of tetanus admitted to the Equine Clinic of the University of Liege between 1991 and 2006. The cases were divided into two groups according to the outcome (survivors and non-survivors). METHODS: The clinical data of survivors and non-survivors were compared using an ANOVA (continuous data) or a Fisher's test (discrete data). RESULTS: The survival rate was 32%. Most animals were 5 years or younger, and none had been appropriately vaccinated. The non-survivors were significantly younger than the survivors. The development of dyspnoea, recumbency, and the combination of dysphagia, dyspnoea, and recumbency was observed significantly more in the non-survivors than in the survivors. The timing of tetanus antitoxin administration (either immediately after the onset of suggestive signs or after a delay) was not different between the two groups. The time between the occurrence of a wound and the first signs ranged from 2 days to 2 months and was not significantly different between groups. All non-survivors died within 8 days of the first signs. CONCLUSIONS & CLINICAL IMPORTANCE: This study suggests that young animals are affected more often and more severely by tetanus than older animals. Dyspnoea, recumbency, and the combination of dysphagia, dyspnoea, and recumbency can be considered as indicators of a poor prognosis in equids suffering from tetanus. [less ▲]

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