References of "Adam, Stéphane"
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See detailCalifornia Verbal Learning Test (CVLT) - Adaptation française
Hahn-Barma; Adam, Stéphane ULg

in Hugonot-Diener, Laurence; Barbeau, Emmanuel; Michel, Bernard (Eds.) et al GREMOIRE: Tests et échelles de la maladie d'Alzheimer et des syndromes apparentés (2008)

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See detailTâche de Rappel Indicé à 48 items (RI-48)
Adam, Stéphane ULg

in Hugonot-Diener, L.; Barbeau, Emmanuel; Michel, Bernard (Eds.) et al GREMOIRE: Tests et échelles de la maladie d'Alzheimer et des syndromes apparentés (2008)

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See detailRetrieval induced forgetting in normal aging
Hogge, Michaël; Adam, Stéphane ULg; Collette, Fabienne ULg

in Journal of Neuropsychology (2008), 2

The retrieval-induced forgetting (RIF) paradigm was used to assess the integrity of unintentional inhibitory functioning in normal aging. The paradigm was adapted to explore the RIF effect under ... [more ▼]

The retrieval-induced forgetting (RIF) paradigm was used to assess the integrity of unintentional inhibitory functioning in normal aging. The paradigm was adapted to explore the RIF effect under conditions that allow us to differentiate the contribution of intentional and automatic retrieval processes to performance. The results showed the presence of equivalent and significant RIF effects in young and older adults, for both the controlled and automatic retrieval performance. These results suggest that unintentional inhibitory processes are spared in normal aging, and confirm that RIF effect is independent of the kind of memory processes needed to perform the task. [less ▲]

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See detailEpreuve de Rappel Libre à 15 items avec remémoration sélective - RLS-15
Adam, Stéphane ULg

in Hugonot-Diener, L.; Barbeau, Emmanuel; Michel, Bernard (Eds.) et al GREMOIRE: Tests et échelles de la maladie d'Alzheimer et des syndromes apparentés (2008)

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See detailLes corrélats métaboliques des processus contrôlés en mémoire dans la maladie d'Alzheimer très débutante
Bastin, Christine ULg; Kerrouche, Nacer; Lekeu, Françoise ULg et al

in Ergis, Anne-Marie; Fiori, N.; Chaby, L. (Eds.) et al Xème colloque international sur le vieillissement cognitif (2008)

Les processus contrôlés et automatiques de récupération mnésique ont été évalués au moyen de la Procédure de Dissociation des Processus appliquée à une tâche de complètement de trigrammes chez 59 patients ... [more ▼]

Les processus contrôlés et automatiques de récupération mnésique ont été évalués au moyen de la Procédure de Dissociation des Processus appliquée à une tâche de complètement de trigrammes chez 59 patients diagnostiqués comme « questionable Alzheimer’s disease » (QAD ou Mild Cognitive Impairment). Par ailleurs, le métabolisme cérébral du glucose des patients a été mesuré par FDG-PET. Comparativement à des volontaires âgés sains appariés, le profil mnésique des patients QAD était caractérisé par un déficit des processus contrôlés, mais une préservation des processus automatiques. Après un suivi de 30 mois, 27 des patients ont développé une maladie d’Alzheimer, tandis que 23 patients restèrent des QAD stables (9 sujets n’ont pas complété le suivi ou ont reçu un autre diagnostic au terme de celui-ci). Les deux sous-groupes présentaient le même degré de déclin des processus de mémoire contrôlés. Des corrélations cognitivo-métaboliques, ainsi qu’une analyse en composantes principales, ont permis de montrer que les corrélats métaboliques des processus contrôlés (à l’entrée dans l’étude) n’étaient les mêmes chez les patients qui allaient développer la maladie d’Alzheimer et chez les patients qui allaient rester stables. Chez les patients qui développaient ultérieurement une maladie d’Alzheimer, l’utilisation correcte des processus contrôlés était positivement corrélée à l’activité du cortex préfrontal dorsomédian, qui pourrait jouer un rôle dans les processus réflexifs de monitoring agissant sur les produits de la récupération. L’activité du cortex préfrontal dorsomédian était corrélée à l’activité métabolique des régions frontales bilatérales et du cortex cingulaire postérieur. Par contraste, chez les patients QAD stables, nous avons trouvé une corrélation avec la formation hippocampique antérieure, une région qui intervient dans la réactivation de l’épisode d’encodage des événements. [less ▲]

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See detailNew learning in dementia: transfer and spontaneous use of learning in everyday life functioning. Two case studies.
Bier, Nathalie; Provencher, Veronique; Gagnon, Lise et al

in Neuropsychological Rehabilitation (2008), 18(2), 204-35

The purpose of these two case studies was to explore the effectiveness of learning methods in dementia when applied in real-life settings and the integration of new skills in daily life functioning. The ... [more ▼]

The purpose of these two case studies was to explore the effectiveness of learning methods in dementia when applied in real-life settings and the integration of new skills in daily life functioning. The first participant, DD, learned to look at a calendar with the spaced retrieval method to answer his repeated questions about the current date and calls made to family. Progressive cuing was used by his wife to increase spontaneous use of the calendar, but DD had difficulty integrating the calendar into his routine. The second patient, MD, relearned a leisure activity (listening to music on a cassette radio) and how to participate in a social activity (saying the rosary in a group) with a combination of learning methods. Transfer of these skills in similar contexts was difficult for MD. She never integrated the cassette radio into her daily life routine but she went regularly to the rosary activity, which was cued by an alarm clock. In sum, the learning methods used were very effective with these patients but transfer and spontaneous use were difficult. Since these aspects are essential to rehabilitation, they should be further explored in order to increase the effectiveness of cognitive interventions. [less ▲]

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See detailFace-name association learning in early Alzheimer's disease: a comparison of learning methods and their underlying mechanisms.
Bier, Nathalie; Van der Linden, Martial ULg; Gagnon, Lise et al

in Neuropsychological Rehabilitation (2008), 18(3), 343-71

This study compared the efficacy of five learning methods in the acquisition of face-name associations in early dementia of Alzheimer type (AD). The contribution of error production and implicit memory to ... [more ▼]

This study compared the efficacy of five learning methods in the acquisition of face-name associations in early dementia of Alzheimer type (AD). The contribution of error production and implicit memory to the efficacy of each method was also examined. Fifteen participants with early AD and 15 matched controls were exposed to five learning methods: spaced retrieval, vanishing cues, errorless, and two trial-and-error methods, one with explicit and one with implicit memory task instructions. Under each method, participants had to learn a list of five face-name associations, followed by free recall, cued recall and recognition. Delayed recall was also assessed. For AD, results showed that all methods were efficient but there were no significant differences between them. The number of errors produced during the learning phases varied between the five methods but did not influence learning. There were no significant differences between implicit and explicit memory task instructions on test performances. For the control group, there were no differences between the five methods. Finally, no significant correlations were found between the performance of the AD participants in free recall and their cognitive profile, but generally, the best performers had better remaining episodic memory. Also, case study analyses showed that spaced retrieval was the method for which the greatest number of participants (four) obtained results as good as the controls. This study suggests that the five methods are effective for new learning of face-name associations in AD. It appears that early AD patients can learn, even in the context of error production and explicit memory conditions. [less ▲]

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See detailWhat is the impact of the explicit knowledge of sequence regularities on both deterministic and probabilistic serial reaction time task performance?
Stefaniak, Nicolas ULg; Willems, Sylvie ULg; Adam, Stéphane ULg et al

in Memory & Cognition (2008), 36(7), 1283-98

The aim of this study was to explore the role of prior explicit sequence knowledge by comparing its influence on serial reaction time (SRT) performance with either a deterministic or a probabilistic ... [more ▼]

The aim of this study was to explore the role of prior explicit sequence knowledge by comparing its influence on serial reaction time (SRT) performance with either a deterministic or a probabilistic sequence. The results confirm that, with a deterministic sequence, preliminary explicit learning improves SRT performance. On the other hand, with a probabilistic sequence, the results show no advantage for SRT performance in explicit-learning conditions. In addition, by using the process dissociation procedure (Jacoby, 1991), we show that performance on a subsequent generation task was more sustained by controlled processes for participants in the explicit-learning conditions than for those in the incidental condition. On the whole, these results, showing that the influence of explicit knowledge can be suppressed in certain specific conditions, are consistent with the intervention of both implicit and explicit mechanisms in SRT tasks, and the results also show that their relative influence can be modulated by the particular demands of the task. [less ▲]

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See detailEtude d'un cas d'aphasie progressive primaire
Adam, Stéphane ULg

Scientific conference (2007, November 27)

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See detailThe ecological validity of traditional memory evaluation in relation with controlled memory processes and routinization
Dubreuil, P.; Adam, Stéphane ULg; Bier, N. et al

in Archives of Clinical Neuropsychology (2007), 22(8), 979-989

The neuropsychological evaluation of memory by traditional tests raises questions about their ecological validity, as the results on these tests often have little relation to the memory complaints. In an ... [more ▼]

The neuropsychological evaluation of memory by traditional tests raises questions about their ecological validity, as the results on these tests often have little relation to the memory complaints. In an attempt to explain this lack of relationship, the present study had two objectives: (1) explore the ecological superiority of the Process Dissociation Procedure (PDP) over traditional memory tests and (2) explore the effects of routinization on the relationship between memory complaints and memory tests. Thirty-three participants aged 55-86 years were given the PDP (memory evaluation), two questionnaires evaluating daily memory complaints (QAM and CDS) and a questionnaire evaluating routinization (EPR). The results indicate that the PDP, with its measure of controlled processes, is more ecological than traditional memory tests for elderly people. As well, the participants' lifestyle (routinized versus non-routinized) influenced their results on memory tests. The results are discussed in relation to neuropsychological evaluation and rehabilitation. (C) 2007 National Academy of Neuropsychology. Published by Elsevier Ltd. All rights reserved. [less ▲]

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See detailUse of a computerised phasic alertness task as a measure of objective cognitive fatigue in multiple sclerosis
Adam, Stéphane ULg; Delrue, Gaël; Caps, Emilie et al

Poster (2007, October 13)

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See detailThe nature and evolution of working memory deficits in multiple sclerosis
Delrue, Gaël; Caps, Emilie; Gryglewicz, Céline et al

Poster (2007, October 12)

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See detailLa réserve cognitive: impact des activités de loisirs, professionnelles et physiques
Adam, Stéphane ULg

Scientific conference (2007, October 04)

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See detailComparison of inhibitory functioning in mild Alzheimer's disease and frontotemporal dementia
Collette, Fabienne ULg; Amieva, Hélène; Adam, Stéphane ULg et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2007), 43(7), 866-874

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and ... [more ▼]

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and inhibitory deficits are also prominent in patients with FTD. However, few studies have simultaneously explored and compared inhibitory abilities in both degenerative diseases. Consequently, the aim of this study was to compare verbal and motor inhibitory processes in the initial stages of AD and the frontal variant of FTD. Stroop and Go/No-go tasks were administered. The results demonstrate that, on the Go/No-go task, AD and FTD patients do not produce more errors than control subjects. However, both groups are impaired on the Stroop task (mainly with regard to the error score) but do not differ from each other. These results indicate that AD and FTD patients do not present a general impairment of their inhibitory abilities. Moreover, these two kinds of dementia present similar quantitative and qualitative inhibitory impairments on the two tasks, although their patterns of structural and functional cerebral impairments are known to be different. The presence of similar inhibitory deficits despite very different patterns of brain damage is in agreement with the hypothesis that inhibitory dysfunction in the two groups of patients depends on a disconnection process between anterior and posterior cerebral areas, rather than on the presence of focal metabolism decreases in different regions. [less ▲]

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See detailOptimization of encoding specificity for the diagnosis of early AD: The RI-48 task
Adam, Stéphane ULg; Van der Linden, Martial ULg; Ivanoiu, A. et al

in Journal of Clinical & Experimental Neuropsychology (2007), 29(5), 477-487

The aim of this study was to evaluate the discriminant validity of the RI-48 test, a shorter French version of the Category Cued Recall portion of the Double Memory Test developed initially by Buschke and ... [more ▼]

The aim of this study was to evaluate the discriminant validity of the RI-48 test, a shorter French version of the Category Cued Recall portion of the Double Memory Test developed initially by Buschke and colleagues (1997), in the diagnosis of mild and very mild Alzheimer disease (AD). The distinctive feature of the RI-48 task is that encoding specificity was increased by adding an immediate cued recall stage at the encoding phase. The results show that the RI-48 task seems to be well adapted to the clinical context and to have good psychometric properties, in particular a lack of a ceiling effect. Moreover, this task appears to be especially well suited for the diagnosis of both mild and very mild AD (sensitivity of 93% and 83.8%). From a more theoretical point of view, this study confirms the importance of optimizing the encoding specificity for the diagnosis of very mild AD, since the more encoding specificity is accentuated, the more discriminating power is increased for the diagnosis of very mild AD. [less ▲]

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See detailLes outils neuropsychologiques sensibles pour le diagnostic précoce de la maladie d'Alzheimer
Adam, Stéphane ULg

Conference given outside the academic context (2007)

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See detailMémoire procédurale et maladie d'Alzheimer: Rôle des fonctions exécutives
Adam, Stéphane ULg

Scientific conference (2007, May 11)

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See detailControlled processes account for age-related decrease in episodic memory
Vanderaspoilden, Valérie; Adam, Stéphane ULg; Van der Linden, Martial ULg et al

in Acta Psychologica (2007), 125(1), 20-36

A decrease in controlled processes has been proposed to be responsible for age-related episodic memory decline. We used the Process Dissociation Procedure, a method that attempts to estimate the ... [more ▼]

A decrease in controlled processes has been proposed to be responsible for age-related episodic memory decline. We used the Process Dissociation Procedure, a method that attempts to estimate the contribution of controlled and automatic processes to cognitive performance, and entered both estimates in regression analyses. Results indicate that only controlled processes explained a great part of the age-related variance in a word recall task, especially when little environmental support was offered. (c) 2006 Elsevier B.V. All rights reserved. [less ▲]

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