References of "Nuzillard, Jean-Marc"
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See detailMoandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae)
Verpoorte, Robert; Frederich, Michel ULg; Delaude, Clément et al

in Phytochemistry Letters (2010), 3

Moandaensine contains a rare anhydronium base subunit. It presents a moderate antiplasmodial activity with IC values of 11.2 microM and 9.2 microM against , respectively, the chloroquino sensitive FCA 20 ... [more ▼]

Moandaensine contains a rare anhydronium base subunit. It presents a moderate antiplasmodial activity with IC values of 11.2 microM and 9.2 microM against , respectively, the chloroquino sensitive FCA 20 GHA and chloroquino resistant W2 strains of Plasmodium falciparum [less ▲]

Detailed reference viewed: 82 (32 ULg)
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See detailChrysopentamine, an antiplasmodial anhydronium base from Strychnos usambarensis leaves
Frederich, Michel ULg; Cristino, Assunção; Choi, Young Hae et al

in Planta Medica (2004), 70(1), 72-76

A new derivative of strychnopentamine was isolated from the leaves of Strychnos usambarensis. This compound, named chrysopentamine, was identified by detailed spectroscopic methods (UV, IR, HR-ESI-MS, 1D ... [more ▼]

A new derivative of strychnopentamine was isolated from the leaves of Strychnos usambarensis. This compound, named chrysopentamine, was identified by detailed spectroscopic methods (UV, IR, HR-ESI-MS, 1D and 2D NMR). Chrysopentamine presented an original hydroxy substitution on C-14 and an aromatization of the ring D of strychnopentamine leading to anhydronium base proper-ties and exhibited strong antiplasmodial properties (IC50 less than 1 muM). [less ▲]

Detailed reference viewed: 48 (10 ULg)